(Records of Medicinal Plants in China)

Different names: Rattan root, Dioscorea zingiberensis, Cynanchum bungeanum, Herbicides, South Snake root, Sparganum burmannii, Hedyotis japonica (Hunan Medicinal Records), Rattan wood (Guangxi Medicinal Plant Directory), Red Herb, Red Purple Root and Rattan grass (Jiangxi Herbal Manual).

The source is the root, leaf and flower of Celastraceae plant Tripterygium wilfordii.

Plant morphology tripterygium wilfordii

Climbing vines, 2 ~ 3 meters high. Branchlets are reddish brown, angular, with oblong tubercles and rusty brown villi. Simple leaves alternate, sub-leathery, ovoid, elliptic or broadly ovoid, 5 ~10cm long and 3 ~ 5cm wide, with tapering apex, rounded or broadly wedge-shaped base, serrate edges, smooth upper surface, light green lower surface, slightly raised main veins and lateral veins on both sides of the leaves, and rusty brown pubescence on the veins: the petiole is about 5mm long and the surface is densely rusty brown. Flowers are small, white, terminal or axillary panicles with 5-lobed calyx; Petals 5, elliptic; Stamens 5, filaments wide near the base, inserted at the edge of cup-shaped disk; Ovary superior, trigonous, short style, head-shaped stigma. Samara, membranous, round or slightly truncated at the apex, round at the base, about 1.5 cm long, about 1 cm wide, yellow-brown, 3-sided, and usually with seeds 1 grain in the center. The seeds are slender and linear. The flowering period is from May to June. The fruit ripening period is from August to September.

Born in shady, wet and slightly fat hillsides, valleys, stream bushes and secondary miscellaneous forests. Distributed in Zhejiang, Jiangxi, Anhui, Hunan, Guangdong, Fujian, Taiwan Province and other places.

Collect summer and autumn harvest.

The chemical constituents of the root contain alkaloids such as triptolide, triptolide, triptolide, triptolide and triptolide.

In addition, tripterygium wilfordii also contains Celastrus alcohol, Celastral alcohol, triptolide, glucose, tannin and so on.

Pharmacological action and insecticidal action

Both the water extract and ethanol extract of Tripterygium wilfordii have the ability to poison the pear leaf caterpillar and leaf roller. However, its petroleum ether, ether or methane trioxide immersion liquid has no insecticidal ability.

Toxic tripterygium wilfordii has different toxicity to various animals. It is very toxic to people, dogs, pigs and insects, and can cause poisoning or even death, but it is not toxic to sheep, rabbits, cats, rats and fish. Tripterygium wilfordii has two effects on the body: one is on the local gastrointestinal tract; The second is the damage to the central nervous system (including thalamus, midbrain, medulla oblongata, cerebellum and spinal cord) after absorption, and the bleeding and necrosis of liver and heart. It is said that tripterygium wilfordii mainly poisons the heart of animals, but it is also toxic to other smooth muscles and striated muscles, which is the cause of death by poisoning. The first aid measures after poisoning are vomiting, gastric lavage, * * *, catharsis and other general methods, but the biological detoxification method using sheep blood or rabbit stomach extract has not been determined. The toxic components of tripterygium wilfordii can be leached by ether, but the toxicity disappears completely after reduction.

Sexual taste "Hunan Pharmacology": "Bitter, great poison."

Indications: "Insecticidal, anti-inflammatory, detoxification."

This product is highly toxic. It should be taken with caution.

Prescription ① Treatment of Rheumatoid Arthritis: The roots and leaves of Tripterygium wilfordii are mashed and applied externally, and they will be removed after half an hour, otherwise they will blister. (Jiangxi Herbal Manual)

② Treatment of itchy skin: Tripterygium wilfordii leaves, mashed and applied. (Hunan Pharmacology)

③ Treatment of waist sores: Tripterygium wilfordii flower and Lindera root, grinding and rubbing the affected area. (Hunan Pharmacology)

Clinical application ① Treatment of leprosy reaction

Thoroughly remove the inner and outer skins from the dry roots of Tripterygium wilfordii, and slice the xylem to dry. For every 4 yuan, add 2,500 ml of water, simmer (uncovered) for 3-4 hours, take 250 ml of brown liquid medicine, and take it in the morning and evening, with 3-4 days as a course of treatment. In Ceng Zhi, all kinds of leprosy reactions 167 cases (including 27 cases of tuberculosis type and 40 cases of tumor type/kloc-0) were controlled after taking 2 ~ 3 doses.

② Treating rheumatoid arthritis.

Use tripterygium wilfordii hook. (Take xylem, as above) for 5 yuan, add 400 ml of water, and decoct with slow fire for 2 hours (without covering) to get liquid medicine 150 ml, and decoct the residue with water to get 100 ml, and take it twice in the morning and evening after mixing, with 7 ~10 days as a course of treatment, and stop taking medicine for 2 ~ 0 days during the course of treatment. Among them, 44 cases were improved or relieved in different degrees.

③ Treating tuberculosis and other chronic lung diseases.

Collect roots in late summer and early autumn, wash, dry and chop. Every 31.2g of Tripterygium wilfordii is added with water1000ml, and decocted with slow fire until it is about 500ml (so that every kloc-0/0ml contains 0.62g of crude drugs). Start taking orally 1 5 ~ 20ml three times a day, with1week as a course of treatment; Depending on the patient's condition and physical condition, the dosage can be slightly increased or decreased, but the dosage should not exceed10 ~ 25ml each time. If there is no obvious side effect after 7 ~10 days, the medication time can be prolonged; However, those who take it for too long should stop taking it for a short time, and generally stop taking it for 5 to 7 days after taking it for 20 to 30 days. After 99 cases were treated, most of the patients' symptoms such as cough, expectoration, fever and asthma were relieved to varying degrees. Take the medicine according to the prescribed dose during the course of treatment, and there is basically no side effect; If the physique is weak, there may be nausea, gastrointestinal discomfort and chills.

④ Poisoning and detoxification

Tripterygium wilfordii is a highly toxic drug, especially the skin is extremely toxic. When using it, the skin should be strictly peeled off, including the double skin and the skin in the tree seam. According to the research of relevant units, tripterygium wilfordii has two effects on the body: one is the local * * * effect on the gastrointestinal tract; One is the damage to the central nervous system including hypothalamus, midbrain, medulla oblongata, cerebellum and spinal cord after absorption, and can cause bleeding and necrosis of liver and heart. The common symptoms of poisoning seen in clinic are dizziness, palpitation, weakness, nausea, vomiting, abdominal pain and diarrhea. Pain in liver and kidney, bloody feces, etc. For the sake of prudence, patients with organic diseases such as heart, liver, kidney and stomach and pregnant women should be banned; When nausea, vomiting, abdominal pain, abdominal distension, pain in liver and kidney, abnormal protein and serum transaminase in urine occur, the drug should be stopped immediately. After poisoning, the general first-aid measures include vomiting, gastric lavage, catharsis, taking 4 liang of fresh radish juice or stewing 8 liang of radish seeds, and using fresh leek juice or strong tea and sheep blood to detoxify. According to the observation of more than 20 cases of poisoning, the symptoms of poisoning are abdominal pain, vomiting, diarrhea, howling and struggling, but no fever. Most deaths occur within 24 hours, no more than 4 days at most. If emetic and laxative are used within 4 hours after taking tripterygium wilfordii, they can generally recover.

Remind you: Tripterygium wilfordii is a Chinese herbal medicine from the Internet. Please follow the doctor's advice before using it.