The specific method is as follows: from July to August, in the well-bred Rehmannia glutinosa field planted in the spring of that year, select the rhizome with strong growth and no diseases and insect pests, dig it up and fold it into short sections of 4-5 cm, air dry it slightly, replant it in a field with sufficient sole fertilizer according to the row spacing10-30 cm and the plant spacing of 5-10 cm, and weed and topdressing it appropriately after rain. Generally, it is best to plant Rehmannia glutinosa when the average daily temperature is18 ~ 21℃. For example, Beijing is in the first and middle of April, Chongqing is in the late February to the late March, and Henan early spring Rehmannia glutinosa is in the first and middle of April; Late Rehmannia glutinosa (or Rehmannia glutinosa after wheat) is from early May to early June. When planting, ditch the ridge or border with a spacing of 33cm, and plant one section every15 ~ 20 cm, cover it with soil for 3 ~ 4 cm, and water it after compacting the topsoil. Plant 2 rows in each ridge and 3-4 rows in each border. After the seedlings are fully planted, make up the seedlings in rainy days, and evenly distribute the seedlings about 1 month after planting, and leave 1 plant healthy seedlings in each hole. Before sealing, shallow shovel the seedlings for 2-3 times, and shovel off the surplus seedlings that have been born one after another. Topdressing should be applied 1 time after each intertillage, and manure or cake fertilizer can be applied. In rainy season, attention should be paid to drainage and waterlogging prevention, so that there is no water in the ground, and buds should be removed at any time.
When cultivating Rehmannia glutinosa, it is not advisable to choose the land where cotton, sesame, beans and melons have been planted, otherwise the disease will be serious. If you want to mix crops, you should choose Gramineae crops; Rehmannia glutinosa has "three fears", that is, fear of drought, fear of waterlogging and fear of pests and diseases. Because of its few roots and poor water absorption capacity, it is easy to wither when it is slightly dry; If the soil moisture is too much, the fleshy roots will rot easily. Therefore, proper irrigation is needed. Source: fresh or dried root tuber of Rehmannia glutinosa, a plant of Scrophulariaceae. Excavate in autumn, remove reed head, fibrous root and sediment, and use it rarely; Or slowly bake Rehmannia glutinosa until it is about 80% dry. The former is known as fresh rehmannia, while the latter is known as raw rehmannia.
Processing: (Radix Rehmanniae Preparata) ⑴ Take clean Radix Rehmanniae, stew it with wine until the wine is completely absorbed, take it out, air dry it until the mucus on the skin is slightly dry, cut it into thick pieces or pieces, and dry it. Every 100kg of radix rehmanniae, 30 ~ 50 kg of yellow wine is used. (2) Take clean Radix Rehmanniae, steam it until it is black and moist, take it out, sun it until it is about 80% dry, cut it into thick slices or blocks, and dry it.
Nature and taste: fresh rehmannia: sweet, bitter and cold. Radix Rehmanniae: sweet, cold. Rehmannia glutinosa: sweet, slightly warm.
Meridian tropism: heart tropism, liver tropism and kidney tropism.
Indications: Rehmannia glutinosa is cool, sweet and bitter, and has the effects of nourishing yin and tonifying kidney, nourishing blood and replenishing blood, and cooling blood. It is quite beneficial for people with yin deficiency, blood deficiency and kidney deficiency to eat it. In addition, Rehmannia glutinosa has the effects of strengthening the heart and diuresis, relieving fever and diminishing inflammation, promoting blood coagulation and lowering blood sugar.
Fresh rehmannia root: clearing away heat and promoting fluid production, cooling blood and stopping bleeding. It can be used for treating yin injury due to fever, red tongue, polydipsia, macula and rash, hematemesis, epistaxis, and sore throat.
Rehmannia glutinosa: clearing heat and cooling blood, nourishing yin and promoting fluid production. It can be used for treating fever, red tongue, polydipsia, yin deficiency, internal heat, bone steaming and fatigue, internal heat to quench thirst, hematemesis, epistaxis, macula and rash.
Rehmannia glutinosa: nourishing yin and blood, replenishing essence and filling marrow. It can be used for treating yin deficiency of liver and kidney, soreness of waist and knees, hot flashes due to bone steaming, night sweats and nocturnal emission, thirst quenching due to internal heat, blood deficiency and sallow, palpitation, irregular menstruation, metrorrhagia and bleeding, dizziness, tinnitus and premature graying of hair and beard.
Usage and dosage: fresh rehmannia root:12 ~ 30g. Radix Rehmanniae and Radix Rehmanniae Preparata: 9 ~15g.
Storage: Fresh Rehmannia glutinosa is buried in sand to prevent freezing; Rehmannia glutinosa is placed in a ventilated and dry place to prevent mildew and moth.
Common formula
⑴ For treating typhoid and epidemic febrile diseases, it is necessary to sweat instead of sweating blood, and epistaxis can not stop vomiting blood, with blood stasis, yellow face, black stool and blood stasis: one or two rhinoceros horns, eight or two rehmannia root, three or two peonies and two or two peonies. The right four flavors are finely cut, with nine liters of water and three liters of water, which are divided into three servings. ("Qian Jin Fang" Rhinoceros Horn Dihuang Decoction)
⑵ Treating restless night sleep due to deficiency of pulse due to summer heat, red tongue due to thirst, and sometimes harsh words, eyes often can't be closed, or joy can't be opened: rhinoceros horn San Qian, Radix Rehmanniae five money, Radix Scrophulariae San Qian, bamboo leaf heart one money, Radix Ophiopogonis San Qian, Radix Salviae Miltiorrhizae two money, Coptis one money five cents, Flos Lonicerae San Qian and Fructus Forsythiae two money (for heart-to-heart use). Eight cups of water, three cups of boiled water, three times a day. You can't talk to someone with a white and slippery tongue. (Qingying Decoction in Treatise on Epidemic Febrile Diseases)
⑶ Treating yang by multiplying yin, resulting in hematemesis and epistaxis: raw lotus leaf, raw mugwort leaf, raw cypress leaf and raw rehmannia root are equally divided. Go to research, the pill is as big as a chicken. Take one pill each time and decoct with water. ("Women's Recipe" Sisheng Pill)
(4) Treatment of hematemesis: one liter of Rehmannia juice and one or two pieces of rhubarb in Sichuan (filed, slightly fried). Mix the herbs together, fry until half a liter, and divide them into two servings, which are taken after warm food. ("Shenghuifang")
5. Treating lung injury and hematemesis: eight liang of Radix Rehmanniae (grinding juice) and one liang of Colla Cervi (drying, grinding into powder). For the first two flavors, the boy urinates five times, and then decocts them in a bronze vessel. Then, the rehmannia juice and gum powder are added, beaten evenly, and decocted to melt. After boiling for ten times, they are divided into three servings. (Dihuang Drink in Shengji Zonglu)
(6) Tonifying deficiency and removing heat, and removing carbuncle and hemorrhoid: Rehmannia glutinosa should be pounded and pressed three times as much as it is needed, and the juice should be taken to the limit. When the soup is cooked in the bronze ware, it should not be covered, which will make you discouraged, and it will be halved. When it comes out, the cloth will be twisted to remove coarse pieces and make me dirty, and it will be even more fried, and the wine will be served as a pill. On the third day. ("Qian Jin Fang" Dihuang Decoction)
(7) Treating fatigue, thin bones, steaming, cold and fever in the evening, coughing and spitting blood: Radix Rehmanniae juice combined. Boil rice congee, stir the familiar rehmannia juice evenly, and eat it in the hollow. ("The Doctor's Heart Mirror")
⑻ Treating postpartum collapse, the bleeding is not stopped, and the mind is upset: half a small cup of Rehmannia juice, half a small cup of motherwort. Take the medicine, add a small cup of wine, fry for three or five times, and take it frequently in three servings. (Yellow rice wine from Shenghuifang)
(9) Curing thirst: three Jin of Radix Rehmanniae (finely cut), half a Jin of ginger (finely cut) and two Jin of Radix Ophiopogonis (removed from the heart). The first three flavors are mashed in a stone mortar, and the raw cloth is twisted in a natural way. It is simmered slowly and thickened, stored in a magnetic box, and melted with warm soup every time, regardless of time. (Rehmannia Decoction in Shengji Zonglu)
⑽ Treatment of broken hands and feet caused by falling off a horse is very painful: one catty of Radix Rehmanniae and four ounces of ginger. Mash the fine powder, stir-fry with a pound of it, wrap the wound with cloth when it is hot, and it will be easy when it is cold, so as to relieve the pain first and then set the bone. ("Yi Jian Zhi")
Chinese patent medicines: Liuwei Dihuang Pill, Liuwei Dihuang Capsule, Jiuzi Dihuang Pill and Gandi Dihuang Pill.
clinical application
⑴ Daochi Powder (Direct Formula of Pediatric Medicine Syndrome) is mainly used for treating heart meridian fire syndrome. Radix Rehmanniae 6g, Akebia Akebia 6g, and Radix Glycyrrhizae 6g. The medicine is the end, 9g each time, one cup of water, and the bamboo leaves are decocted together until five minutes, and then taken warm after eating. Rehmannia glutinosa in the prescription enters the heart and kidney meridian, which is sweet, cool and moist, clearing away heat and nourishing blood and yin, and is used as a minister.
⑵ Qingwei Powder (Lanshi Secret Collection) is mainly used for toothache caused by stomach fire. Radix Rehmanniae 6g, Radix Angelicae Sinensis 6g, Cortex Moutan 9g, Rhizoma Coptidis 6g, Cimicifuga 9g. At the end of the medicine, make one serving, half a cup of water, fry until seven points, and then take it cold. Radix Rehmanniae in the prescription cools blood and nourishes yin.
⑶ Danggui Liuhuang Decoction (Lanshi Secret Collection) is mainly used for night sweats due to yin deficiency and excessive fire. Radix Angelicae Sinensis, Radix Rehmanniae, Scutellariae Radix, Cortex Phellodendri, Rhizoma Coptidis and Radix Rehmanniae Preparata each 6g, and Radix Astragali 12g. The medicine is coarse powder, each time 15g, two cups of water, decocted to one cup, taken before eating, and taken by half for children. Angelica sinensis, Radix Rehmanniae and Radix Rehmanniae in the prescription enter the liver and kidney to nourish yin and blood, and the yin blood can make fire, which is the monarch medicine in the prescription.
⑷ Liuwei Dihuang Pill (Direct Formula for Children's Medicine Syndrome) is used to treat kidney yin deficiency syndrome. Weakness of waist and knees, dizziness, tinnitus and deafness, night sweats, nocturnal emission, thirst quenching, bone steaming hot flashes, hand and foot heart fever, dry tongue, sore throat, teeth shaking, heel pain, and children with halogen door incompatibility, red tongue with little coating, and deep and rapid pulse. 24g of Radix Rehmanniae Preparata, each of Corni Fructus and Rhizoma Dioscoreae 12g, and 9g of Alismatis Rhizoma, Cortex Moutan and Poria. The top is the end, and the honey is the pill, which is as big as the buttonwood. Take three pills (6 ~ 9g) each time, and melt them in hollow warm water. In the prescription, Radix Rehmanniae tastes sweet and pure yin, enters the kidney meridian, is good at nourishing yin and tonifying kidney, and fills the essence, which is the monarch medicine.
⑸ Taishan Panshi Powder (Complete Collection of Ancient and Modern Medical Systems) is used to treat the syndrome of weak qi and blood and unstable fetus. Restlessness of fetal movement, abortion, slippery fetus, pale complexion, fatigue, lack of appetite, pale tongue with thin white fur, slippery and weak pulse. Ginseng Radix and Radix Astragali each 3g, Atractylodis Rhizoma, Radix Glycyrrhizae Preparata each 1.5g, Radix Angelicae Sinensis 3g, Rhizoma Chuanxiong, Radix Paeoniae Alba and Radix Rehmanniae Preparata each 2.4g, Radix Dipsaci 3g, a pinch of glutinous rice, Scutellariae Radix 3g and Fructus Amomi1.5g. Decoct with water. In the prescription, Rehmannia glutinosa is used to replenish blood and nourish yin to nourish fetus, and ginseng is used to restore the essence of qi and blood deficiency, which is the monarch drug.
[6] Zuo Guiwan (Jing Yue Quan Shu) treats the syndrome of deficiency of true yin. Backache and leg weakness, dizziness, deafness and insomnia, nocturnal emission, spontaneous sweating and night sweats, dry mouth and tongue, red tongue with little coating, and thready pulse. Dahuai Radix Rehmanniae Preparata 240g, Yam 120g, Lycium barbarum 120g, Cornus officinalis 120g, Radix Cyathulae 120g, Semen Cuscutae 120g, Colla Cervi 120g, and Colla Plastrum Testudinis/kloc-0. On the table, the cooked rehmannia root is steamed and smashed into paste, and honey is refined into pills, which are as big as buttonwood. 9g each time, before eating, take it with boiling soup or light salt soup. It can also be decocted in water, and the dosage should be reduced according to the original proportion. In the prescription, Rehmannia glutinosa is used to nourish yin and kidney, and the essence is filled, which is the monarch medicine.
Literature discussion
(1) Materia Medica: Rehmannia glutinosa, the Classic only talks about dry and raw, and those who don't talk about cooked, such as blood deficiency, fatigue and heat, postpartum deficiency and heat in the elderly, and those who need Rehmannia glutinosa, often worry about severe cold if they live and dry, and so on, so later generations switch to cooked people.
⑵ Zhang Yuansu: Rehmannia glutinosa can tonify the kidney, which is necessary for those with blood failure. Subumbilical pain, which belongs to the kidney meridian, cannot be removed unless it is prepared by rehmannia glutinosa, but it is also a medicine for clearing the kidney.
⑶ Li Gao: Rehmannia glutinosa is used to treat heart heat in hands and feet and heart heat, which can benefit kidney water and treat blood. It is suitable for those with heavy pulse. If the pulse is weak, it is appropriate to prepare rehmannia glutinosa. Rehmannia glutinosa is steamed by fire, so it can tonify the kidney and invigorate the vitality.
⑷ "Compendium": According to Shark Wang's Yi Jian Fang, it is said that men with more yin deficiency should use Radix Rehmanniae Preparata, and women with more blood heat should use Radix Rehmanniae. There is another cloud: Radix Rehmanniae can give birth to seminal blood, Radix Asparagi can be introduced into the place where it was born, Radix Rehmanniae can supplement the seminal blood, and Radix Ophiopogonis can be introduced into the place where it is supplemented. Yu Tuan's True Story of Medicine says: Rehmannia glutinosa gives birth to blood, but the fear of the weak stomach gas will hinder food. Rehmannia glutinosa nourishes blood, while those who drink phlegm are afraid of mud diaphragm. Or clouds, yellow rice wine fried with rehmannia root may be good for the stomach, but fried with rehmannia root ginger juice is not muddy, so it is necessary to use Huang Zhi subtle people.
[5] "Materia Medica": The cultivated land is slightly warmer, and its work is more pu. Long-term illness and yin injury, new blood loss, are also necessary. However, the nature of the two places is cool and muddy. If you have diarrhea after childbirth, you can't use it even if you see fever and lochia, but if you misuse it, you will be discharged. Rehmannia glutinosa is prohibited for cough due to yin deficiency, bone steaming due to internal heat, or vomiting blood, and at the sight of weak spleen and stomach, false stool, or diarrhea at dawn, postpartum diarrhea, postpartum anorexia, and illness. Where the chest diaphragm is full of phlegm, the airway is unfavorable, and the ascending and descending is suffocating, the medicine should be passed but not delayed, and Rehmannia glutinosa is also forbidden in the soup pill. If there is a qi syndrome that can be used when it is not necessary, it is also possible to use Gui Xin with less assistance. If phlegm syndrome is necessary, stir-fry it with ginger juice.
[6] Ben Cao Zheng: Rehmannia glutinosa has a flat nature and a pure and quiet smell, so it can tonify the true yin of the five internal organs, and it is most important in the bloody viscera, so it is not the spleen and stomach. Besides, the reason why my wife is alive is that she has ears of qi and blood. Qi governs yang and moves, while blood governs yin and calms. Ginseng is the main method of invigorating qi, while qi and surgery can be supplemented by Tamenosuke. Rehmannia glutinosa is the main way to replenish blood, while Xiongxiong and Guidan can be Tamenosuke. However, in Qi, Shu, Xiong and Gui, it is necessary to avoid it, while Ginseng and Radix Rehmanniae are indispensable for qi and blood. Therefore, those who are deficient in Yang in various meridians must be Ginseng, and those who are deficient in Yin and blood in various meridians must be Rehmanniae. Those who suffer from deficiency of true yin have fever, headache, thirst, laryngitis, expectoration, panting, or vomiting due to cold of spleen and kidney, or blood in the mouth and nose due to deficiency of fire, or water flooding on the skin, or discharging benefits due to yin deficiency, or yang floating and being manic, or yin falling off and prostrating, and those who are distracted due to yin deficiency are not able to gather together unless they are prepared by rehmannia. The fire rising due to yin deficiency is not heavy enough to fall; Those who are restless due to yin deficiency are not calm enough to calm down; Those who are just anxious due to yin deficiency cannot be relieved by the sweetness of the cultivated land; Those who suffer from yin deficiency and excessive water evil, how can they give up their cultivated land for self-control? Those who suffer from yin deficiency and lose their true qi, why should they give up their cultivated land and return to their source? For those who suffer from yin deficiency and lose both essence and blood, and the fat cream is thin, why should Rehmannia glutinosa be thick in the stomach and intestines, and there are still the most mysterious and wonderful ones, then Rehmannia glutinosa and powder can sweat, and why should sweat be turned into blood without yin? Rehmannia glutinosa and warming agent can only return to yang, why? Yang is born in the next place, and nothing can be done without recovery. However, the positive rate is fast, so ginseng can be used less, and it can be successful. The negative rate is slow, and there are not many cultivated land, which is difficult to work. Nowadays, people are afraid of stagnation, so why does Cui Shi use Shenqi Pill to treat phlegm floating? If there are people who are afraid of its smoothness, then why does Zhongjing use Bawei Pill to treat kidney diarrhea? If the method of making and using ginger juice is used to stir fry, there will be moderate cold and vomiting. If it is useful to make Amomum villosum, there must be fullness before it can be done; Those who use wine to stir fry must have meridian stagnation before they can. If those who don't have this number want to use the method forcefully, it is that those who don't know how to use the prepared rhizome of rehmannia just want to use its quietness and gravity, but instead, they want to move around to confuse their nature, so what's the difference between painting a snake and adding feet? Today's people want to use yin and must also use seepage, so how do they know that yin is not good for water, water is not good for yin, and the method of filling is not suitable for seepage; That is, if the blood is useful to replenish blood and it is suspected to be stagnant and greasy, how can we know that blood deficiency is like dry soil, and the drought is extremely longing for Yun Ni, while the exhausted intestine is extremely happy (moist). If you don't know this, you should use it less and still want to benefit both, and who dares to use it alone and let it be more; If you don't dare to use it alone, who dares to help you to give full play to your strengths? What's the difference?
⑺ "Drug Meaning": Rehmannia glutinosa, steamed with wine, tastes bitter and turns sweet, and the nature is cool and warm, and the liver is specially assigned to replenish blood. Because the liver is bitter and anxious, use it slowly, and warm the gallbladder, which can benefit the hard work and tonify the kidney. It is suitable for those who have insufficient internal injuries, work hard, worry about blood, indulge in excessive consumption of essence, regulate menstruation and give birth. It is a holy medicine for calming the five internal organs, regulating blood circulation, moistening the skin, nourishing the mind, calming the soul, nourishing the yin, and sealing the bone marrow. It is a turbid product with a strong smell to nourish the liver and kidney. Therefore, all raw Radix Rehmanniae Preparata, Radix Asparagi, Radix Ophiopogonis, Carapax et Plastrum Testudinis preparata, Radix Angelicae Sinensis, Fructus Crataegi, and Achyranthis Radix are sticky and moistened with nourishing yin and blood.
⑻ "Ben Jing Feng Yuan": Rehmannia glutinosa, steamed by fake fire, turns bitterness into sweetness, and is the yang in the yin, so it can tonify the kidney and invigorate the vitality. It must be steamed and dried many times. If it is cooked, it will be beneficial without steaming or exposure. ..... Subumbilical pain, which belongs to kidney essence injury; Tibial and femoral acid, which is insufficient in the lower yuan; If you don't see anything in your eyes, it's a water deficiency that can't be identified. It's all a disease dominated by the kidney, and it can't be removed unless it's cultivated land.
⑼ "Seeking Truth from Materia Medica": Jing Yue is the most clear on the theory of Radix Rehmanniae Preparata, and it is one of the most serious concerns that the spleen and kidney cold are turned into vomiting, and rehmannia can be used to treat it. Since the husband has spleen deficiency and cold, the spleen and kidney are already tired from cold, so they should be used for pungent heat, thinking that sweeping away, such as when the sun comes, the hard ice will dissolve itself, but the frost and snow will be dropped again, and the yin agent will not make the cold even worse. Although it is said that the cultivated land is warm, the cold dissipates from the warm, but the cold is the highest and the reverse is vomiting, then the cold is already very cold. Is there the temperature of the cultivated land, which can make the cold disperse outside? However, either the yang is abundant and the yin is slight, and the yang turns into yin, occasionally catching a cold. It may be effective if it is mixed with warming and dispersing; If there is no fire in pure yin, vomiting is caused by syncope, which is a deep taboo.
⑽ Reading of Materia Medica: Zhang Jingyue took the kidney as the master of all diseases, and mistakenly took Rehmannia glutinosa as the top grade in Shenyi Materia Medica Classic. He thought that the medicine for treating diseases moistened and glued, which led to the accumulation of evil spirits in shaoyin and there was no way out. In the future, although he took ginger, attached it with no heat, took Qin, did not even have cold, took ginseng, did not make up the technique, and took nitrate and yellow, what was the reason? Covered with the glue of Rehmannia glutinosa, women are pregnant with Siwu decoction, and the medicine that breaks through will not hurt them. With the help of Rehmannia glutinosa in Siwu decoction, we can understand its harm of protecting the fetus, and its sticky nature is the best, such as oil in the face, which can't be removed once it is worn.
⑾ "Materia Medica Justice": Rehmannia glutinosa is a good agent for tonifying the middle energizer and enriching the blood. Guheng used it to dry, so it is called dried rehmannia, which is the so-called original place today. However, the Classic is unique in this taste, and it is said that the living are especially good, which means that the fresh ones speak, and it can be known that the dry land and the fresh land were divided into two categories before the Six Dynasties, but the identification of indications was not very strict. To "A Bie Lu of Famous Doctors", the birthplace of Huangyitiao was changed, which was obviously different from that of dried rehmannia root. Its main indications were that the dry person supplemented blood and benefited yin, while the fresh person cooled the serum fire, and the skill was treated, so it was no longer mixed. However, it is a cold product, but it is suitable for deficiency and heat. If the true yin is not full and there is no heat syndrome, dry land is used, which is still too feminine, which is not conducive to the weak spleen and stomach. Therefore, since the Tang and Song Dynasties, there has been a method of making Radix Rehmanniae Preparata, which is mixed with Amomum villosum and wine, steamed and dried for many times until the center is pure black and extremely ripe. Then, the true yang of the sun is used to change its feminine nature, so that those who are weak in the middle can take it, and they will not suffer from stagnation and difficulty. Therefore, Radix Rehmanniae Preparata is known as mild temperature, which can tonify the true yin, and does not worry about its cold, cool and slippery discharge. It is based on clearing the heart and stomach. Where the body fluid is depleted, blood is scarce, sweating and spermatorrhea are lost, and blood deficiency is not recovered after large blood loss and postpartum, it is very effective to take large doses frequently. However, if it is sticky and turbid, if it is taken by the body with great deficiency, it will also hinder transportation. Therefore, those who are satisfied with their stomachs are good, and their form and spirit are not withered, and they can be tolerated. Otherwise, they will suffocate in Zhongzhou, which will lead to bloating. Although there is Amomum villosum mixed with steaming, it is also useless, and the middle qi is too weak, and exercise has no right. Rehmannia glutinosa can replenish yin and blood, but its effect can't be falsely claimed. However, it can only be used for taking and nourishing those who are deficient in yuan after illness and whose true yin is thin. Nowadays, it is just right for many people to enter the nourishing ointment. If the person's stomach is thin and weak, it will be full of food, and even bloated, and its harm is quite shallow, and the phlegm is diffuse, or it is accompanied by exogenous factors.
⑿ "Pearl Capsule": Tonifying deficiency of blood, dredging blood vessels and benefiting qi.
[13] Wang Haogu: The Lord sits and wants to get up without seeing anything.
[14] "Compendium": filling bone marrow, growing muscles, producing essence and blood, nourishing five internal organs and internal injuries, dredging blood vessels, benefiting eyes and ears, blackening beard and hair, five injuries and seven injuries in men, uterine leakage in women's injuries, irregular menstruation, and various fetal diseases.
⒂ "Materia Medica from the New": nourishing kidney water, sealing and filling bone marrow, benefiting blood vessels, nourishing true yin, hearing and eyesight, black hair and beard. It can also tonify swollen yin, relieve chronic diarrhea, treat fatigue, wind, arthralgia, fever due to yin deficiency, cough with phlegm, shortness of breath and shortness of breath, empty feeling in the stomach, acne-induced heart abscess, pain in the tibia and thigh after illness, acute pain in the umbilicus and abdomen after delivery, feeling yin deficiency, closing without sweat, all kinds of dynamic powers, all liver and kidney yin deficiency, and deficiency of all diseases, so it is the main drug for strengthening water. Rehmannia glutinosa as food has a long history among the people. As early as more than 1000 years ago, the people in the Central Plains Rehmannia glutinosa production area "pickled Rehmannia glutinosa into pickles, soaked in wine and made tea." Up to now, people still shred Rehmannia glutinosa into cold salad and cook porridge to eat.
Avoid crowds
Edible: It is suitable for patients with fever due to yin deficiency, thirst in mouth, constipation due to yin injury, deficiency of kidney yin, dry throat pain due to deficiency of fire, eczema, neurodermatitis, irregular menstruation, bloody collapse, restless fetal movement and other diseases.
Avoid eating: people with spleen deficiency, diarrhea and stomach deficiency are not suitable for eating. At the same time, Rehmannia glutinosa should not be eaten with Allium macrostemon, Allium tuberosum, radish and scallion, and copper and iron utensils should not be used when frying. The chemical constituents of Rehmannia glutinosa are mainly glycosides, among which iridoid glycosides are the main ones. The iridoid glycosides isolated from fresh rehmannia glutinosa include leonuride, aucubin, catalpol, rehmannia glutinosa, b, c, d, melitoside and melitoside. 8- epiloganic acid, ajugoside, 6-O-E- feruloyl ajugol, 6-O-Z- feruloyl ajugol. 6-O6-O-vanilloyl ajugol, 6-O- p-coumaroyl ajugol, 6-O-(4 "-O-α-L-rhamnose is the medicine glycoside) vanillyl ajugol. Catalpol has the highest content. There are also sugars: D- glucose (D-glucose), D- galactose (D-galactose), D- fructose (D-fructose), sucrose (Sucrose), raffinose (Raffinose), stachyose, mannose trisaccharide (amn-ninoTCMLIBiose). It also contains lysine, histidine, arginine, asapartic acid, glutamic acid, threonine, serine, glycine, alanine, valine, Amino acids such as isoleucine, leucine tyrosine, phenylalanine, γ -aminobutyric acid, glucosamine, D- glucoside alcohol, Phosphoric acid, β -sitosterol (β-siterol), daucosterol, 1- ethyl -β-D-galacetoside, adenoside and inorganic elements.
Roots contain rehmannioside)A glycosides A, B, C, D, dihydrocatalpol, aucubin, catalpol, Melittoside and leonuride．. Fresh roots contain catalpol glycoside 0.11%.The alcohol extract of fresh roots also contains β-sitosterol, mannitol, daucosterol, 1- ethyl -β-D- galactoside and sucrose. The water-soluble components contain various sugars, among which water is the most important. It is 32.1%~ 48.3%, and contains many kinds of amino acids, among which arginine has the highest content, which is 2% ~ 4.2%. In addition, Y-aminobutyric acid, phosphoric acid, a small amount of β-sitosterol, stigmasterol and a small amount of rapeseed sterol have been separated from commercial Rehmannia glutinosa. A series of fatty acids, β-sitosterol, palmitic acid, succinic acid, carrot glycoside and trace rapeseed sterol have been separated from dried Rehmannia glutinosa. ⑴ Hypoglycemic: The effective part of Rehmannia glutinosa (R-BP-F) is injected intraperitoneally, which has hypoglycemic effect on alloxan-induced experimental diabetes in mice.
⑵ Hemostasis: Rehmannia glutinosa, Rehmannia glutinosa decoction, Rehmannia glutinosa charcoal and Rehmannia glutinosa charcoal can shorten the blood coagulation time in mice (capillary method).
⑶ Anti-disseminated intravascular coagulation: 70% methanol extract of Rehmannia glutinosa inhibits ADP-induced platelet aggregation in rats, and has antithrombin effect, which has an antagonistic effect on endotoxin-induced disseminated intravascular coagulation in rats.
In addition, it has anti-inflammatory immunity and anti-liver damage effects.
⑷ Treatment of hepatitis: Clinical report shows that the combination of Rehmannia glutinosa and Glycyrrhiza uralensis Fisch, whether intramuscular injection or oral administration, has a certain effect on infectious hepatitis, promoting the recovery of liver function, especially the significant decrease of ALT without local and systemic adverse reactions.
5. Treatment of diphtheria: Rehmannia glutinosa as the main ingredient, combined with anti-diphtheria mixture of Fructus Forsythiae, Scutellariae Radix, Radix Ophiopogonis and Radix Scrophulariae, the fever subsided within 4 days after taking it, the false membrane disappeared and the sore throat improved. Microscopic characteristics: the cork layer in the cross section of fresh rehmannia glutinosa is several layers of cells. Thin-walled cells in cortex are loosely arranged; Scattered with many secretory cells, containing orange oil droplets; Occasionally there are stone cells. The phloem is wider and there are fewer secretory cells. Form a layer and form a ring. Xylem rays are broad; The ducts are sparse and radially arranged.
Radix Rehmanniae powder is dark brown, cork cells are light brown, and the cross section is rectangular and arranged neatly. The parenchyma cells are round and contain round nuclei. Secretory cells are similar in shape to common parenchyma cells and contain orange or orange oil droplets. The diameter of the duct with marginal holes and reticulation is about 92 microns.
Physical and chemical identification: Take 2g of Rehmannia glutinosa, add 20ml of methanol, put it in a water bath, heat and reflux 1 hour, let it cool, filter, and recover methanol from the filtrate to 5ml as the test solution. Another catalpol reference substance was added with methanol to prepare a solution containing 0.5 mg per ml as the reference substance solution. According to the experiment of thin-layer chromatography, absorb 5 microliters of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, use chloroform-methanol-water (14: 6:1) as the developing agent, unfold, take them out, dry them, spray anisaldehyde test solution, and heat them at 105℃ until the spots become clear. In the chromatogram of the test sample, the spots of the same color appear in the corresponding position of the chromatogram of the control sample.
Rehmannia glutinosa powder 1 g is added with ethanol 10 ml, soaked for 24 hours, filtered, and the filtrate is used as the test solution. Another 5-hydroxymethylfurfural reference substance was added with ethanol to make a solution containing 0.5 mg per ml as the reference substance solution. Absorb 0/0 microliter of the test solution/kloc-0 and 5 microliters of the control solution, respectively spot them on the same silica gel GF254 thin plate, use petroleum ether-ethyl acetate as the developing agent, unfold, take them out, dry them, and examine them under ultraviolet lamp. In the chromatogram of the test sample, spots with the same color appear in the position corresponding to the chromatogram of the control sample.