The aim of treatment is primarily to prevent further deposition of amyloid and to promote its resorption, and reducing the production of precursor proteins has a marked effect on slowing progression of the disease. In AA amyloidosis, treatment of the underlying disease may cause amyloid deposits to subside, such as treatment of rheumatoid arthritis with alkylating agents, and treatment of familial Mediterranean fever with colchicine, which protects renal function from damage. Tumor resection can also sometimes dissipate amyloid. However, treatment with cytotoxic drugs to inhibit the growth of plasma cells is less effective in AL amyloidosis. After renal transplantation in patients with hemodialysis-associated amyloidosis, β2-M can be rapidly normalized and amyloid deposits dissipate. Liver transplantation has been successfully used to treat familial amyloidotic polyneuropathy caused by mutations in the TTR gene.AL amyloidosis involving the heart can be considered for chemotherapy or heart transplantation. In conclusion, there is no effective treatment for this disease, and supportive therapy is still the mainstay, and organ failure should be actively dealt with.

In recent years, with the emergence of new drugs and clinical testing methods, the treatment of amyloidosis has made great progress. Relying on the academician platform, the Nephrology Department of Nanjing General Hospital of the Chinese People's Liberation Army is the earlier unit in China to carry out autologous stem cell transplantation for the treatment of AL amyloidosis, and the number of cases involved has exceeded 50 with satisfactory treatment results. The following link is the report of a typical case from our department by the CCTV10 station, which is available for interested patients.