1. Drugs 1: anti-aldosterone. Clinical studies have proved that spironolactone can significantly reduce the mortality of CHF, prevent myocardial interstitial fibrosis and improve hemodynamics and clinical symptoms on the basis of routine treatment. Combined with ACE inhibitor, it can reduce the levels of Ang Ⅱ Ⅱ Ⅱ and aldosterone at the same time, and further reduce the mortality and the incidence of ventricular arrhythmia, with better effect.
2. Drug 2: diuretic. Promote the excretion of Na+ and H2O, reduce blood volume, reduce cardiac preload and improve cardiac function; Reduce venous pressure, eliminate or alleviate venous congestion and its pulmonary edema and peripheral edema, especially suitable for CHF patients with edema or obvious congestion.
3. Drug 3: Beta blockers. Beta blockers can block cardiac beta receptors, antagonize the toxic effect of excessive catecholamine on the heart, improve myocardial remodeling, reduce renin release, inhibit RAAS, up-regulate cardiac beta receptors to restore their signal transduction ability, and improve the sensitivity of beta receptors to catecholamine. For dilated cardiomyopathy and ischemic congestive heart failure, long-term application can prevent the aggravation of clinical symptoms, improve cardiac function and reduce the incidence of sudden death and arrhythmia, but it is not suitable for people with severe bradycardia and hypotension.
Matters needing attention
People with heart failure must be more careful in the choice of drugs, and during the medication, they should also pay attention to eating more light, digestible and less irritating foods.