Fish testis, also called fish white, is an organ for fish to make and store sperm. Fish white contains a special protein called protamine, which is the simplest alkaline protein in nature. This is a good medicine to stop bleeding.

In fact, "fish white" is not "fish semen". Yellow croaker is much more common. There are caviar in the belly and fish white in the belly. Those with fish eggs are females, and those with fish white are males. There are two fish whites. Wrapped in film, it tastes slightly astringent but delicious after cooking. It can be seen that "fish white" is not the semen of fish, but the reproductive organs of male fish.

Extended data:

First, the effect:

Fish white contains a special protein called protamine, which is the simplest alkaline protein in nature. This is a good medicine to stop bleeding. Protamine is not only used to treat massive hemorrhage caused by pulmonary hemoptysis and severe hepatitis, but also can combine with sulfate group of anticoagulant heparin, so that heparin quickly loses anticoagulant activity.

Protamine can be mixed with insulin, antibiotics, adrenocortical hormone and other drugs to prolong the curative effect of these drugs. For a patient who needs to inject insulin three times a day, if protamine zinc insulin injection made of protamine and zinc is used, the insulin injection interval can be extended to every 24-48 hours 1 time. ?

Fish testicles contain a lot of DNA. Tablets and injections made of DNA can be used to treat leukopenia caused by anticancer drugs or radiotherapy, as well as aplastic anemia, thrombocytopenia, hepatitis, psoriasis and other diseases. Arginine is an extract from fish testis, which is a specific drug for treating hepatic coma.

Second, the application of protamine:

1, the application in food

An important feature of protamine is its antibacterial property, so its application in food is mainly used to develop a natural preservative. The early research results show that protamine has obvious inhibitory effect on the reproduction of gram-positive bacteria, but has little effect on eukaryotic microorganisms such as gram-negative bacteria, mold and yeast.

Later, some researchers think that protamine has little to do with Gram reaction, but it has broad-spectrum antibacterial activity, and has obvious inhibitory effect on Gram-positive bacteria, molds and yeasts, and can inhibit the growth of Bacillus subtilis, Bacillus megaterium and Bacillus licheniformis.

2. Medical application

At present, protamine plays an important role in clinical medicine and has been used in pharmaceutical industry for many years. Protamine sulfate extracted from fish testis is the only anti-heparin drug in heart surgery under cardiopulmonary bypass, which can resist the anticoagulant effect of heparin or synthetic anticoagulants, and can be used as an antidote for these anticoagulants in clinic.

Protamine can combine with a variety of protein to form a complex, such as protamine combined with insulin, which can prevent or delay the release of insulin and prolong its hypoglycemic effect, so it can be developed into protamine insulin zinc salt hormone preparation with hypoglycemic effect.

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