When poisonous mushrooms are eaten by mistake, they should be treated as early as possible, otherwise they will cause serious consequences. When treating a poisoned patient, the first consideration should be to help the patient eliminate the poison from the body to prevent the toxin from continuing to be absorbed and aggravating the condition. Detoxification at the early stage of poisoning is necessary and effective for all types of poisoning. Emetic: Physical or pharmacologic emetic can be used. Such as first let the patient take a lot of warm saline, available 4% warm saline 200~300ml or 1% magnesium sulfate 200ml, 5~10ml once, and then can use chopsticks or nails not long fingers (preferably with a cloth wrapped around the fingertips) (safe objects) to stimulate the pharynx, prompting the vomiting; or in the guidance of the medical staff, with copper sulfate, tulip syrup, injection of apo-morphine hydrochloride and other medicinal emetic. Note that pregnant women should be careful with emetic. Gastric lavage: severe vomiting does not need gastric lavage, such as vomiting a small number of times should not give up gastric lavage. The sooner the gastric lavage, the better, generally in the ingestion of poisonous substances within 4 ~ 6 hours gastric lavage effect is best. However, even if it takes more than 6 hours, or even 12 to 18 hours, gastric lavage can still be performed according to the absorption status of the poison. Gastric lavage is usually performed with slightly warm boiled water and saline. Potassium permanganate solution (1:2000-5000) can also be used, after gastric lavage, activated carbon can be instilled as adsorbent, the use of which is to take 30~50g and put it into 500ml of lukewarm water and mix it into suspension, and then inject it into the stomach by mouth or gastric tube for several times, or use egg white to adsorb the poison. Diarrhea: In order to clear the poison staying in the intestinal tract, 10% magnesium sulfate can be taken orally for diarrhea, but patients with central nervous system, respiratory, cardiac inhibition or renal dysfunction should not use magnesium sulfate. The use of magnesium sulfate can form hypermagnesemia, causing magnesium poisoning. Sodium sulfate is usually better for diarrhea. Mannitol or sorbitol can also be used as a laxative, especially after instillation of activated carbon, to increase the efficacy of elimination of unabsorbed poisons. Oral administration of 30-60 ml of castor oil as a laxative has also been suggested. Enema: Saline or soapy water can be used as high enema for patients without diarrhea. Each time 200-300ml, 2-3 times in a row. Infusion and diuresis: large amount of infusion can be used in the early stage in order to make the toxin excreted from the urine in large amount. Infusion can be used 10% dextrose, saline, etc., and at the same time, intravenous diuretics should be applied, usually 20-40mg of tachycardia or 250ml of 20% mannitol is used for static injection, which can be repeated several times if necessary. However, attention should be paid to enter the fluid balance, but also pay attention to water, electrolyte balance and potassium chloride supplementation for patients with low potassium.
Treatment of different types of poisoning
The above is the general treatment after poisoning by poisonous mushrooms. In the process of actual treatment, some different treatments should be taken according to different types of poisoning at the same time of the above treatments: Gastroenteritis type: it can be dealt with according to the above general treatment, especially in the early stage of inducing vomiting, gastric lavage and diarrhea to accelerate the discharge of poisons. Neurological and psychiatric types: in poisoning of poisonous mushrooms containing toxocarpine, muscarinic-like symptoms may be seen, and atropine may be used; in poisoning of poisonous mushrooms containing isoxazole derivatives, psychosis, hallucinations and other disorders may be seen, and sedatives may be used; in poisoning of poisonous boletus, causing psychiatric symptoms such as hallucinations of small people, and psychiatric anomalies may be handled according to psychiatric anomalies. Treatment with chlorothiodiphenylamine. Hemolytic type: the drugs used in the treatment of this type of poisoning are prednisone, cortisone, sodium bicarbonate, etc. Severe anemia can be treated with adrenocorticotropic hormone or blood transfusion.