sā n q and pi à n 2 English Reference
sanqi tables [Terminology Committee of Traditional Chinese Medicine. Terminology of Traditional Chinese Medicine (24)] 3 National Essential Medicines
National Essential Medicines Retail Guidance Price InformationNo. of Sanqi Tablets
CatalogueNo. Drug Name, dosage form and specifications Unit Retail refers to
Guide price category Remarks 6 46 Sanqi Tablets 2 tablets (sugar-coated) boxes (bottles) 3.3 Chinese patent medicine parts * (referring to the dosage of 4-12 tablets at a time, Three times a day) 61 46 Sanqi tablets 12 tablets (sugar-coated) box (bottle) 2 Chinese patent medicine part 62 46 Sanqi tablets 24 tablets (sugar-coated) box (bottle) 4 Chinese patent medicine part 63 46 Sanqi tablets 3 tablets (sugar-coated) box (bottle) 4.9 Chinese patent medicine part 64 46 Sanqi tablets 36 tablets (sugar-coated) box (bottle) Divided into 65 46 Sanqi tablets 4 tablets (icing) boxes (bottles) 6.5 Chinese patent medicine part 66 46 Sanqi tablets 45 tablets (icing) boxes (bottles) 7.3 Chinese patent medicine part 67 46 Sanqi tablets 48 tablets (icing) boxes (bottles) 7.7 Chinese patent medicine part 68 46 Sanqi tablets 5 tablets (icing) boxes (bottles) 8. 9 46 Sanqi tablets 6 tablets (sugar-coated) box (bottle) 9.6 Chinese patent medicine part 61 46 Sanqi tablets 1 tablets (sugar-coated) box (bottle) 15.7 Chinese patent medicine part 611 46 Sanqi tablets 18 tablets (sugar-coated) box (bottle) 16.9 Chinese patent medicine part
Note:
1. Note column in the table.
2. Specifications of dosage forms marked with "△" in the remarks column in the table, and other specifications of the same dosage form are provisional prices.
3. The dosage form specifications are indicated in the remarks column. The prices of other specifications in this dosage form are based on the same usage and dosage, and are calculated according to the Drug Price Comparison Rules.
4. The "honey pills" marked in the dosage form column in the table include small honey pills and big honey pills. 4 Overview
The main component of Sanqi tablets is panax pseudo-ginseng [1].
The Drug Standards of the Ministry of Health of the People's Republic of China contains the ministerial standards of 37 tablets.
the pharmacopoeia of the people's Republic of China (21 edition) records the pharmacopoeia standard of Sanqi tablets. The composition is 5g of Panax notoginseng. It has the effects of removing blood stasis, stopping bleeding, reducing swelling and relieving pain. Used for hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, chest and abdomen tingling, traumatic injury and swelling and pain. Pregnant women should not take it. 5 Pharmacopoeia standard of Sanqi tablets 5.1 name
Sanqi tablets
Sanqi Pian 5.2 prescription
Sanqi 5g 5.3 preparation method
Take Sanqi, pulverize it into fine powder, add appropriate amount of auxiliary materials, make granules, and press it into 1 tablets, or coat it with film (large pieces); Or pressing into 2 tablets (small pieces). 5.4 characteristics
this product is grayish yellow to brownish yellow tablets; Or film-coated tablets, which are grayish yellow to brownish yellow after the coating is removed; Bitter and slightly sweet. 5.5 identification
(1) Take this product and observe it under a microscope: resin duct fragments contain yellow secretions.
(2) Take .5g of this product powder, add 1ml of methanol, shake for 3min, filter, evaporate the filtrate to dryness, and add 1ml of methanol to dissolve the residue, which will be used as the test solution. In addition, take notoginsenoside R1 reference substance, ginsenoside Rb1 reference substance and ginsenoside Rg1 reference substance, and add methanol to prepare mixed solutions containing .5mg each in 1ml as reference solution. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia, 21 edition), absorb 5μl of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, develop them with chloroform-methanol-water (7:3:.5) as developing agent, take them out, air dry them, spray them with 1% sulfuric acid ethanol solution, heat them at 15℃ until the spots become clear, respectively, and spray them on the silica gel G thin-layer plate. In the chromatogram of the test sample, spots with the same color appear in the sunlight at the position corresponding to the chromatogram of the reference sample; Fluorescent spots with the same color under ultraviolet light. 5.6 the inspection
shall comply with the relevant provisions under tablets (Appendix I D of Pharmacopoeia I, 21 edition). 5.7 content determination
according to high performance liquid chromatography (appendix ⅵ d, 21 edition of Pharmacopoeia). 5.7.1 chromatographic conditions and system applicability test
Octadecylsilane bonded silica gel is used as filler; Using acetonitrile as mobile phase A and water as mobile phase B, gradient elution was carried out according to the regulations in the following table; The detection wavelength is 23nm. The theoretical plate number should be no less than 4 according to the R1 peak of Notoginsenoside. Time (minutes) Mobile phase A(%) Mobile phase B(%) ~12 19 81 12~6 19→? 36 81→64 5.7.2 Preparation of reference solution
Take appropriate amounts of ginsenoside Rg1, ginsenoside Rb1 and ginsenoside R1, accurately weigh them, and add methanol to make a mixed solution containing ginsenoside Rg1.4mg, ginsenoside Rb1.4mg and ginsenoside R1.1mg per ml. 5.7.3 preparation of test solution
take 1 tablets of this product, weigh it accurately, grind it finely, take about .8g, weigh it accurately, put it in a conical flask with a stopper, add 5ml of methanol accurately, weigh it, leave it overnight, put it in a water bath at 8℃ for heating and refluxing for 2 hours, let it cool, weigh it again, make up the lost weight with methanol, shake it evenly, and filter it. 5.7.4 determination method
accurately suck 1μl of reference solution and 1μ l of test solution respectively, inject them into a liquid chromatograph, and determine to obtain the product.
based on the total amount of ginsenoside Rg1(C42H72O14), ginsenoside Rb1(C54H92O23) and notoginsenoside R1(C47H8O18), each tablet of this product contains Notoginseng, and the small tablet should not be less than 1.mg and the large tablet should not be less than 2.mg .. 5.8 Functions and indications < P > Dispelling blood stasis to stop bleeding, reducing swelling and relieving pain. Used for hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, chest and abdomen tingling, traumatic injury and swelling and pain. 5.9 Usage and dosage < P > Oral. Small tablets: 4 ~ 12 tablets at a time, large tablets: 2 ~ 6 tablets at a time, 3 times a day. 5.1 note
pregnant women should not take it. 5.11 specifications
each tablet contains notoginseng? (1).25g (small piece)? (2).5g (large piece) stored for 5.12 days < P > sealed. 5.13 edition
Chinese Pharmacopoeia 21 edition 6.1 Pinyin Name
Sanqi Pian 6.2 StandardNo.
WS3B14893
This product is a tablet made of Notoginseng 6.3 preparation method
Take 5g of Notoginseng, pulverize it into fine powder, and add appropriate amount of auxiliary materials to make it. 6.4 characteristics
This product is grayish yellow or brownish yellow tablets; Bitter and slightly sweet? 6.5 Identification
(1) Take this product and observe it under a microscope: resin duct fragments contain yellow secretions; Tapered, reticulated and threaded conduits are 15 ~ 55μ m in diameter.
(2) Take 1 tablet of this product, grind it, add 1ml of methanol, shake it for 3 minutes, filter, evaporate the filtrate, and add 1ml of methanol to the residue to dissolve it, and use it as the test solution. In addition, the reference substances of human saponins Rb1, Rb1 and Notoginseng saponins R1 were taken, and methanol was added to make a mixed solution containing 2.5mg each in 1ml as the reference substance solution. According to the test of thin-layer chromatography (page 57 of Appendix), absorb 1μl of each of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, use the lower layer solution of 1,2 = chloroethane, n-butanol and methanol water (3:4:15:25) as the developing agent, unfold, take out, air dry, spray with 1% sulfuric acid ethanol solution, and bake at 15℃ for about 5 minutes. In the chromatogram of the test sample, spots of the same color appear at the positions corresponding to the control chromatogram. 6.6 the inspection
shall conform to the relevant regulations under tablets (page 11 of appendix). 6.7 extract
take 1 tablets of this product, accurately weigh them, grind them, accurately weigh an appropriate amount (about the weight of 5 tablets), use 7% ethanol as solvent, and measure them according to the cold immersion method under the alcohol-soluble extract determination method (Appendix 47). Each tablet shall contain no less than 9mg of extract. 6.8 Functions and indications < P > Dispelling blood stasis to stop bleeding, reducing swelling and relieving pain. Used for hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, chest and abdomen stabbing pain, traumatic swelling and pain. 6.9 Usage and dosage < P > Take orally, 2-6 tablets at a time, 3 times a day. 6.1 note
pregnant women should not take it. 6.11 storage
sealed. 7 Sanqi Tablet Drug Instructions 7.1 Drug Name
Sanqi Tablet 7.2 Chinese Pinyin
Sanqi Pian 7.3 dosage form
Does each tablet contain Sanqi? (1).25g (small piece)? (2).5g (large area) of 7.4 characters < P > Sanqi tablets are grayish yellow to brownish yellow; Or film-coated tablets, which are grayish yellow to brownish yellow after the coating is removed; Bitter and slightly sweet. 7.5 The main component of Sanqi tablet < P > is made from Panax notoginseng. 7.6 The function of Sanqi Tablet is < P > to disperse blood stasis, stop bleeding, reduce swelling and relieve pain. Used for hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, chest and abdomen tingling, traumatic injury and swelling and pain. 7.7 Usage and dosage of Sanqi tablets < P > Oral. Small tablets: 4 ~ 12 tablets at a time, large tablets: 2 ~ 6 tablets at a time, 3 times a day. 7.8 contraindications of Sanqi tablets < P > Pregnant women should not take it. 7.9 Precautions
1. Avoid cold and greasy food.
2. Children, menstruating and lactating women and the elderly and infirm should take it under the guidance of a doctor.
3. Patients with serious chronic diseases such as hypertension, heart disease, liver disease, diabetes and kidney disease should take it under the guidance of a doctor.
4. If there is more or more bleeding, you should go to the hospital in time.
5. If the symptoms are not relieved after taking the medicine for 3 days, you should go to the hospital.
6. It is forbidden for people who are allergic to Sanqi tablets, and should be used with caution for those who are allergic.
7. Sanqi tablets are forbidden to be used when their properties change.
8. Children must use it under the supervision of adults.
9. Please keep Sanqi tablets out of the reach of children.
1. If you are using other drugs, please consult a doctor or pharmacist before using Sanqi tablets. 7.1 drug interaction
drug interaction may occur if it is used with other drugs at the same time, please consult a doctor or pharmacist for details. 7.11 Remarks