1. Variety: Guangxi cotyledon is Labiatae, and Northeast cotyledon is biennial erect herb.

2. Taste: The leaves and grains of Guangxi Perilla frutescens cotyledon are edible, and the taste is tender, while the leaves and grains of Northeast Perilla frutescens cotyledon are older.

3. Efficacy: Guangxi Perillae Cotyledon is mainly used for clearing away heat and toxic materials, while Northeast Perillae Cotyledon is mainly used for expelling wind and toxic materials and relieving itching.

Generally speaking, although Guangxi cotyledons and Northeast cotyledons are cotyledons, there are still some differences in variety, taste and efficacy. Consumers can choose according to their own needs and tastes when purchasing.