Table of Contents 1 Pinyin 2 English Reference 3 General 4 Latin Name 5 English Name 6 Alias of Bupleurum Chinense 7 Source and Origin 8 Phytomorphology 9 Harvesting 10 Characteristics 11 Aromatic Attributes 12 Functions and Indications 13 Usage of Bupleurum Chinense 14 Precautions for Use 15 Applications 16 Chemical Constituents 17 Pharmacological Actions of Bupleurum Chinense 18 Pharmacopoeial Standard of Bupleurum Chinense 18.1 Name 18.2 Source 18.3 Characteristics 18.4 Identification 18.5 Content Determination 18.5.1 Chromatographic conditions and system suitability test 18.5.2 Preparation of control solution 18.5.3 Preparation of test solution 18.5.4 Assay 18.6 Wooden Turtle Seed Drinking Tablets 18.6.1 Concoctions 18.6.1.1 Wooden Turtle Seed Kernel 18.6.1.2 Wooden Turtle Seed Cream 18.6.1.2.1 Determination of Containment 18.6.2 Flavours and 18.6.3 Functions and Indications 18.6.4 Methods of Use and Dosage 18.6.5 Precautions 18.6.6 Storage 18.7 Provenance 19 References Attachment: 1 Formulas using the Chinese medicine wood turtle seed 2 Proprietary Chinese medicines using the Chinese medicine wood turtle seed 3 Wood Turtle in Ancient Texts 1 Pinyin

mù biē zǐ

2 English Reference

Momordica cochinchinensis [朗道汉英字典]>>

semen momordicae [朗道汉英字典]>>>

cochinchina momordica seed [湘雅医学专业词典]>>>

Semen Momordicae (拉) [中中醫学名词審定]

Semen Momordicae [中中醫学名词審定]

Semen Momordicae (拉) [Chinese Medicine Nomenclature Review Committee. Committee. Chinese Medicine Nomenclature (2004)]

cochinchina momordica seed [Chinese Medicine Nomenclature Validation Committee. Chinese Medicine Nomenclature (2004)]

3 Overview

Wood turtle seed

Wood turtle seed is the name of a traditional Chinese medicine from Kaibao Chongding Ben Cao [1]. It is the dried mature seeds of Momordica cochinchinensis (Lour.) Spreng. from Cucurbitaceae [2].

The Pharmacopoeia of the People's Republic of China*** and the State Pharmacopoeia (2010 edition) recorded the pharmacopoeial standard of this Chinese medicine.

4 Latin name

Semen Momordicae (La) (Nomenclature of Traditional Chinese Medicine (2004))

5 English name

cochinchina momordica seed (Nomenclature of Traditional Chinese Medicine (2004))

6 Alias of Wooden Turtle Seed

Turtle of Earth, Wooden Turtle [1].

Leak Ling Zi, Vine Tong Zi, Wooden Turtle.

7 Source and origin

The mature seeds of Momordicacochinchinensis (Lour.) Spr. Mainly produced in Guangxi, Sichuan, Hubei. [1]

8 Phytomorphology

Perennial herbaceous vine. Stem angular, glabrous, tendrils single, opposite leaves. Leaves alternate, circular-cordate, 7-14 cm in diam., 3-5-cleft or y cleft, occasionally 7-lobed, lobes ovate or long ovate; petiole with 2-5 glands apically or at the base of the leaf blade. Flowers unisexual and homozygous; male pedicels slender, with 1 large bract per flower, calyx black-brown with yellow-white spots, corolla pale yellow-white; female pedicels short, bracts smaller. Gourd fruit long ellipsoid, 9-15cm long, red when ripe, surface with soft spines. Seeds dark black. Flowering June to August, fruiting August to November.

Born on mountain slopes in the understory or scrub. Mainly produced in Hubei, Guangxi, Sichuan.

9 Harvesting

Mature fruits are harvested in winter, dissected, sun-dried to half dry, remove the pulp, take out the seeds, dry.

10 Traits

Seeds flat plate-like, slightly raised or slightly concave in the middle, 2 to 4 cm in diameter, about 0.5 cm thick/surface gray-brown to black-brown, reticulate pattern, in the edge of a larger tooth-like protuberance on the light yellow umbilicus. The outer testa is hard and brittle, the inner testa is gray-green and tomentose. Cotyledons 2, yellowish white, rich in oil. There is a special greasy gas, bitter taste.

11 Sexual flavor attribution

Bitter, slightly sweet, warm, toxic. Into the liver, spleen, stomach meridian. [1]

12 Functions and Indications

Dispersing knots, subduing swelling, relieving pain, and chasing poison [1].

1. To treat carbuncle, furuncle, mammary carbuncle, scrofula, hemorrhoids swelling and pain, psoriasis, psoriasis, bald sores, bruises and stasis swelling and pain. Apply with vinegar juice or powder. [1]

2. Treatment of rheumatism and paralysis, pediatric chancre, lumps [1].

13 Usage and dosage of wood turtle seeds

Decoction: 0.3-0.9g, usually into the pill, scattered with [1].

14 Precautions for use

Caution should be exercised when taking internally. Pregnant women and the weak should not take. [1]

15 Uses

Mullein root: pounded and applied to treat carbuncle boils, lymphadenitis [1].

16 Chemical composition

wood turtle seed contains a variety of saponins, its glycosides are wood turtle seed acid (Momodic acid), cotton root saponin (Gypsogenin). It also contains 44.38% fatty oil, and the oil contains α-tungstic acid and so on. In addition, also contains oleanolic acid, sterols, alginate, protein and so on. [1]

Containing momordic acid, gypsophila saponins (gypsogenin), oleanolic acid, α-elaeostearic acid, gaseous acid, sterols.

17 Pharmacological effects

The aqueous or alcoholic infusion of wood betony has an antihypertensive effect on anesthetized animals. Oral or subcutaneous injection of wood turtle seed saponin in rats, on the hornbeam gum-induced foot and ankle swelling, has anti-inflammatory effect. Wood betony saponin has hemolytic effect. Woodbury saponin has greater toxicity. [1]

18 Pharmacopoeia standard of Mubiezi 18.1 Name

Mubiezi

Mubiezi

MOMORDICAE SEMEN

18.2 Source

This product is the dried mature seeds of the cucurbit plant Momordica cochinchinensis (Lour.) Spreng. Mature seeds. The ripe fruits are harvested in winter, dissected, sun-dried to half dry, remove the pulp, take out the seeds, and dried.

18.3 Properties

The product is flat and almost plate-like, slightly raised or slightly concave in the middle, with a diameter of 2-4 cm and a thickness of about 0.5 cm. The surface is grayish-brown to blackish-brown, with a reticulate pattern, and there is a light-yellow umbilicus on one of the larger toothed protuberances on the edge. The outer testa is hard and brittle, the inner testa is gray-green and tomentose. Cotyledons 2, yellowish white, rich in oil. It has a special oily odor and a bitter taste.

18.4 Identification

(1) [3] The powder is yellowish gray. The thick-walled cells are elliptic or orbicular, with undulating edges, 51-117 μm in diameter, thick-walled, lignified, and with obvious cell cavities, some of which are narrow. Cotyledon thin-walled cells polygonal, containing fat oil block and paste powder particles; fat oil block class round, diameter 27 ~ 73μm, the surface can be seen reticulate texture.

(2) according to the thin-layer chromatography (2010 version of the Pharmacopoeia, Appendix VI B), absorb [content determination] under the test solution and the control solution of 5ul, respectively, were spotted on the same silica gel G thin-layer plate, trichloromethane methanol and water (8: 2:1) as an unfolding agent, unfolding, take out, air drying, sprayed with 10% sulfuric acid solution of ethanol, heated at 105 ℃ until the spots show color. The color of the spots was clear. In the chromatogram of the test article, in the corresponding position with the chromatogram of the control article, the same color spots.

18.5 Determination of content

Determined by high performance liquid chromatography (2010 Pharmacopoeia, Appendix VI D).

18.5.1 Chromatographic conditions and system suitability test

Octadecylsilane-bonded silica gel as filler; acetonitrile 0.4% phosphoric acid solution (70:30) as the mobile phase; the detection wavelength of 203 nm. Theoretical plate counts should not be less than 6000, according to the calculation of the methyl methyl ester peak of Silymarin saponins 3OβD glucuronide.

18.5.2 Preparation of control solution

The control solution was prepared by taking the silymarin saponins 3OβD glucuronide. Take the appropriate amount of silymarin saponin 3OβD glucuronide methyl ester control, precision weighing, add methanol to make a solution containing 0.5mg per lml | that is obtained.

18.5.3 Preparation of the test solution

Take the wood turtle seed kernel powder about 1.5g, precision weighing, placed in the Soxhlet extractor, add petroleum ether (60 ~ 90 ℃) trichloromethane (1:1) mixture of 60 ml, heating and reflux for 1?2 hours, discarding petroleum ether trichloromethane mixture, filter paper cartridges to exhaust the solvent, placed in the round-bottomed flask, 60% methanol l00ml heating and reflux for 4 hours, the extract evaporation of the solution. Reflux 4 hours, the extract was evaporated. Residue with 10ml of water to dissolve and transfer to a stoppered test tube, add 0.6ml of sulfuric acid, shake well, plug tightly. Place in a boiling water bath heating for 2 hours, remove, cool, filter, discard the filtrate, residue with methanol 8ml to dissolve, transfer to a 10ml flask, add 1 drop of sulfuric acid so that the solution pH to 2, shake well, 50 ℃ water bath for 4 hours, remove, cool, add methanol to make up to the scale, shake well, filtered, and take the filtrate that is obtained.

18.5.4 Determination

Precisely aspirate the control solution and test solution 20ul each, injected into the liquid chromatograph, measurement, it is obtained.

This product is calculated according to the dry product, wood turtle seed kernel containing strophanthidin saponin element 3OβD glucuronide methyl ester (C37H56O10) shall not be less than 0.25% . [3]

18.6 Wood Turtle Seed Tablets 18.6.1 Concoction 18.6.1.1 Wood Turtle Seed Kernel

Remove the shell and take the kernel, and mash it when used [3].

The inner testa of this product is gray-green, downy. Cotyledons 2, yellow-white, rich in oil. It has a special oily odor and bitter taste.

(2) Same as the herb. [3]

18.6.1.2 Wood turtle seed cream

Take clean wood turtle seed kernel, stir-fry it hot, grind it, wrap it in paper and press it to remove the oil.

This product is white or off-white loose powder. It has a special oily odor and a bitter taste [3].

18.6.1.2.1