Introduction of black heart ginger
Chinese medicine alias blue ginger, green ginger, black ginger, black ginger, black ginger Introduction Curcuma caesia Roxb., a plant of the genus Curcuma, family Zingiberaceae, is used as a medicine with rhizomes. It is harvested in summer, washed, used fresh or sliced and dried. Taste and Meridian bitter, pungent, warm. Functions and IndicationsExpel wind and remove dampness, subdue swelling and relieve pain. Used for rheumatic pain, headache, chest pain, abdominal diarrhea and pain; used externally to treat bruises, blood stasis and swelling. Usage and dosage 3-5 money, soaked in wine or boiled in water; external use of appropriate amount, mashed and mixed with wine external application.
The efficacy of black heart ginger
Black heart ginger ( Chinese herbal medicine Botanical name: Hairy Ginger King ) (Plant subject: a kind of wild ginger family)
Alias: blue ginger, blood mother ginger, soil Sanqi.
Botanical name: Hairy turmeric.
Growth environment: this product is a perennial herb, cultivated.
Distribution: India, Vietnam, Malaysia and southern China.
Medicinal Part: Root.
Collection period: throughout the year.
Location: Home grown.
Taste and odor: warm, slightly pungent, fragrant.
Functions: expelling wind and promoting qi, dispersing toxins and subduing swelling, relieving pain, stopping bleeding, and eliminating lumps.
Indications, dosage and usage: 1, postpartum wind: 4 two raw, 1 catty of black vinegar, decoction, dregs can be eaten; 2, postpartum stasis and pain; 3, bruises and stasis, are as above.
Experimental formula 1: (treatment of postpartum and postpartum stasis pain formula) black heart ginger 1 two, one-legged ball 1 two, tempeh ginger 1 two, four bowls of water, decoction into a bowl of service.
(Explanation) This formula uses black heart ginger to dispel wind and dissipate blood stasis to relieve pain, one-legged ball to promote blood circulation, black bean ginger to dispel wind. It is effective for abdominal pain caused by postpartum blood stasis, and postpartum liver blood deficiency, liver wind internal inciting.
(Square song) postpartum stasis pain black heart ginger, one-legged ball with black bean ginger, equal parts of water with the decoction, dispel wind and stasis effect.
Recipe 2: (Treatment of bruises and stasis formula) black heart ginger 1 two, chicken bone incense 1 two, golden cow root 5 money, golden button head 5 money, five clawed dragon root 5 money, four bowls of water, decoction into a bowl of service.
(Explanation) Black heart ginger, gold button head to dispel wind and blood stasis; chicken bone incense, golden cow root to dispel wind, swelling and pain; five-clawed dragon to dredge the blood. Because of the fall and pummeling and internal injuries to the internal organs, external injuries to the sinews and bones into the stasis patients, since the collection of macroeffects.
(Square song) bruises do not have to worry about, black heart ginger and gold button head, five-clawed dragon root chicken bone incense, swelling and pain has a golden calf.
Curcuma longa
Pinyin name ? Sh?
A.K.A. Blue Heart Ginger, Black Heart Ginger, Ginger Seven
A.K.A. Warm Curcuma longa, Pong Curcuma longa, Mountain Turmeric, Taro Seven, Stinky Poop Ginger
A.K.A. Pong Curcuma longa Mau, Pong Medicine, Pong Curcuma longa, Guang Mau, Pong Jiao, Green Ginger, Qiang Qi, Guang Jiao, Black Heart Ginger, Wentong Jiao.
Taste pungent, bitter, warm.
Attributes to the liver and spleen meridians.
Functions and Indications: Promoting circulation of Qi and breaking up blood, eliminating accumulation and relieving pain. It is used in making a fire in the abdomen, blockage, blood stasis, menstrual closure, food accumulation, distension and pain; early cervical cancer.
Functions: Promoting blood circulation, eliminating accumulation and relieving pain. It is used for blood stasis, abdominal pain, swollen liver and spleen, heart and abdominal distension, accumulation, women's blood stasis and menstrual closure, bruises and pain in drinking and food stagnation. (1) Promoting circulation of qi, relieving pain, eliminating blood stasis and eliminating accumulation: it is used for menstrual closure of qi stagnation and blood stasis, chest and hypochondriac pain, abdominal pain and mass in the abdomen, etc. It is often combined with Sanleng. It is often used with San Ling. (2) Eliminating food and resolving stagnation: used for stomach and abdominal distension and pain caused by food stagnation, often combined with burnt malt and burnt betel nut.
Functions and Indications: To move Qi and break the blood; eliminate accumulation and relieve pain. It can be used to treat heartache, heartburn, dietary stagnation, epigastric and abdominal distension, blood stagnation, menstrual cramps, obstruction of the abdomen, lumps and tumors, and bruises
Usage and dosage for internal use: decocted in soup, 3-10g; or in pills and powder. External use: appropriate amount, decoction soup wash; or powdered dressing. It is often used raw to move qi and relieve pain, and it is recommended to be fried in vinegar to break blood circulation and dispel blood stasis.
Usage and dosage for internal use: decoction of soup, 1.5-3 Qian; or into the pill, bulk.
Dosage: 6-9g.
Note that pregnant women are prohibited.
Note that qi and blood deficiency, weakness of the spleen and stomach without accumulation and stagnation should be taken with caution. Pregnant women should not take.
Note that menorrhagia and pregnant women are prohibited.
1. "Leigong concocted medicinal interpretation":? It is forbidden for people with deficiency. 2. "Materia Medica Zheng":? It is not suitable to be used unless there is a firm and stubborn accumulation. 3. "The General Explanation of Medicinal Properties": "It is a medicine for attacking zuozhi. It is a medicine for attacking, and can be used as an adjuvant, but cannot be used for a long time. 4. "Herbal Harm": "It is an antidote to menstruation, and should not be used for a long period of time. All menstruation, and all blood heat for the sick people to avoid.
Pharmacological effects 1.Anti-tumor effect: Curcuma oil preparation in vitro on the mouse Ai's ascites cancer cells, 615 pure line of mice L615 leukemia and ascites-type liver cancer cells and other tumor strains of the growth of the obvious inhibition and destruction of the role of the 100% Curcuma injections 0.3-0.5 ml of intraperitoneal injection to the mice, on sarcoma S180. Above. The monomers obtained from the volatile oil of Curcuma longa, curcumol and curcumodione 75mg/kg when injected subcutaneously, have a high inhibition rate on the mouse sarcoma S37, cervical cancer U14, Ehrlich ascites carcinoma (ECA), the tumor shrinks significantly when the tumor is seen to be surrounded by fibroblasts around the tumor tissues increase, there is a layer of lymphocytes and phagocytes inside the tumor cells surrounded by the immune response appeared. Under the electron microscope, the tumor cells in the treatment group showed a decrease in the ratio of nucleoplasm, the nuclear shape tended to be normal, and the number of chromatin, nucleolus and interchromatin particles was reduced, so it is believed that curcumol has an inhibitory effect on the nuclear metabolism of the cells of mouse sarcoma. In vitro test proved that curcumol and curcumodione have obvious destructive effect on Ehrlich ascites cancer cells, which can make them degenerate and necrotic. Different concentrations of curcuma oil injection have obvious direct destructive effect on tumor cells, with the characteristics of fast and strong action, the more the number of tumor cells, the greater the concentration of the drug solution needed to kill 90% of tumor cells. The anti-cancer effect of Curcuma longa is both direct action and the host's immune response. Clinical curcuma oil for intratumoral injection treatment of cervical cancer, after treatment, tumor tissue can be seen necrosis and shedding, local lymphocyte infiltration, some cases of mass disappearance, cervix smooth, suggesting that curcuma has a direct role in killing tumor cells.
In the pathological section, there are dense small lymphocytes around the cancer cells, a large number of sinusoidal cells in the lymphatic sinus tissue proliferation, and significant elevation of lymphocytes in the blood, all of which suggest that there is a significant immune response in the host in the effective cases. The principle of anticancer effect of Curcuma longa, Curcuma longa oil in addition to the direct tumor killing effect, but also can enhance the tumor cell immunogenicity, thereby inducing or promoting the body's immune rejection of the tumor, experiments have proved that with Curcuma longa-treated ECA and L615. Tumor seedling active immunity, can indeed make part of the animal to obtain obvious protective effect. Further study proved that the active immunoprotective effect of Curcuma L615 tumor strain has certain specificity, because the animals immunized by Curcuma L615 tumors could not produce the cross immunoprotective effect against L795 (which is a new strain of sarcoma leukemia in 615 lineage mice). Some of the animals in the curcuma vaccine-immunized group with significant immunity to L615, despite being able to tolerate 10(-3 )? 10 L615 cells to multiple attacks, yet died from 3 ? 10 L759 tumor cells. And this immunoprotective effect has a certain stability, once established, can be maintained for a fairly long time (10-13 months), but can not be passed on to the offspring, because the vast majority of its offspring (93/94) can not tolerate the attack of 105-3 ?105 L615 cells, all of them developed typical L615, leukemia and died, and the average survival time has not been prolonged, suggesting that this kind of immunoprotective effect of the parents is acquired and acquired, but also can be passed on to the offspring. The average survival time was not prolonged, indicating that this immunoprotective effect in the parent is acquired and cannot be transmitted to the offspring. Pure female T-739 mice were used to observe the radiosensitizing effect of curcuma oil on lung adenocarcinoma (LA-795), and the experimental results proved that the intraperitoneal injection of curcuma oil plus irradiation group had a significant delay in tumor growth compared with the simple irradiation group, and it could increase the effect of radiation therapy by 42%, achieving a moderate sensitizing effect.
2. Anti-early pregnancy effect: Curcuma longa rhizome of alcohol extract and its active ingredients (monoterpenes and sesquiterpenes) on rats, mice have a very significant anti-early pregnancy effect, the dog also has a certain effect of anti-bedding. The antipregnancy effect of Curcuma oil is the most significant, the anti-incarceration and anti-early pregnancy effect of 600-900mg/kg of Curcuma oil injected intraperitoneally and subcutaneously in small arbutus is 7%-90%, the anti-incarceration effect in rabbits injected intraperitoneally with 80mg/kg of Curcuma oil is 80%, and the anti-incarceration effect of 400mg/kg injected vaginally is 100%, and the death of the embryo is generally observed when the drug is administered in the 2-5 days of the conception, the Absorption or blocking of embryo cell implantation. And 7-10 days after conception to give the drug is caused by miscarriage or stillbirth, volatile oil through the subcutaneous, intraperitoneal, vaginal drugs have a certain effect of pregnancy, only the drug effect of fast and slow there are not week. Intraperitoneal injection has a fast onset of action, vaginal administration has a slow onset of action, and the amount of intraperitoneal administration is less than 5 times the amount of vaginal administration. Gavage of mice from Curcuma longa decoction had the same antipregnancy effect. Curcuma oil on mice to stop the process of pregnancy is to prevent the embryonic cells to bed, so that the cessation of development, visible atrophy and degeneration of the embryonic cells free in the uterine cavity, some of the embryonic cells after the death of the bed is in the process of being absorbed.
3. Antibacterial effect: Curcuma longa volatile oil in vitro can inhibit Staphylococcus aureus. - Hemolytic streptococcus, Escherichia coli, typhoid fever, Vibrio cholerae and other growth.
4. Elevation of leukocytes: mice intraperitoneal injection of curcuma oil 10ml/kg, curcumol 0.3% 10ml/kg, for 8d, can significantly counteract the reduction of leukocytes caused by intraperitoneal injection of cyclophosphamide 150mg/kg and promote leukocyte rebound, suggesting that curcuma has a certain role in elevating leukocytes.
5. Cardiovascular effects: Curcuma longa increases blood flow in the femoral artery, the most obvious effect in the activation of blood stasis medicines, blood flow peak increased by 252%, 10 minutes after the use of blood flow increased by 36.0%, the vascular resistance decreased by 66.4%, with curcuma longa oil injection intravenous treatment of thrombotic occlusive vasculitis blood stasis in the patients, along with the improvement of the patient's clinical symptoms, the limb hemodynamic diagram also saw significant improvement.
6. Effect on gastrointestinal smooth muscle: In vitro rabbit intestinal test found that low concentration of Curcuma longa, so that the intestinal tube tension increases, high concentration, on the contrary, the intestinal tube diastole.
7. Hepatoprotective effect: Curcuma longa alcoholic extract and volatile oil on carbon tetrachloride (CCI4) thioacetamide (TAA) induced elevation of alanine aminotransferase (ALT) in mice has a significant reduction in the amount of sulfobromophthalein sodium (BSP) retention is reduced, and the corresponding hepatic histopathy is reduced.
8. The role of acute renal failure: rabbits with 50% glycerol saline 15ml/kg subcutaneous injection caused acute renal failure, the control group, the naked eye can be seen in the kidney swelling and enlargement, was purple and dark color, biopsy microscope observation, can be seen in more purple and dark color stripes of vascular stagnation, stagnation or slowing down of blood flow in the capillaries, the intravenous administration of curcuminoids injection 4ml/kg per day,***3 days after the naked eye did not see a significant kidney, but the blood pressure was reduced. After 3 days, the naked eye did not see obvious swelling of the kidney, and the purple and dark color was lightened or had returned to normal, and the stagnation of striated blood vessels was disappeared under biopsy, and the capillary blood flow was accelerated in the pathological section (FIE), and the control group saw that there was extensive proximal and distal tubular epithelial cell vacuolar degeneration or turbid swelling, and the lumen of the renal tubule was occluded, and part of the epithelium of the tubule was destroyed and detached, and the tubular lumen had a large number of tubular types, and there was stagnation of blood in some of the vessels, and the Curcuma longa was administered intravenously. All the above pathologic changes were significantly reduced 48 hours after curcuma injection, the vacuolation and turbid swelling of the epithelium of the tubules were significantly reduced, the tubular pattern in the lumen of the renal tubules was minimal or disappeared, the blood stagnation in the small blood vessels was reduced or disappeared, and the lumen of the glomerular capillaries was enlarged. General rabbits injected with glycerol about 12 hours after the appearance of soy sauce red urine, urine volume significantly reduced, some no urine, depression, not eating, are in 24-48 hours of death, and curcuma group 24 hours after the increase in urine volume, although the color of the urine is also soy sauce red, but to 48-72 hours after the urine color basically return to light yellow, and no death.
9. Inhibition of platelet aggregation and anti-thrombosis: Curcuma longa aqueous extract 9.0g/kg/day to rats by gavage, ***7 days of ADP-induced platelet aggregation has a significant inhibitory effect, and can significantly reduce blood viscosity, as well as shorten the electrophoresis time of red blood cells. Its hydrotropic alcohol precipitation injection 1.13g/kg intravenous injection also has a very significant inhibitory effect on thrombosis in rats.
10. Anti-inflammatory effect: mice instilled warm tulip volatile oil 200mg/kg of acetic acid produced peritonitis has a very significant inhibitory effect, mice intraperitoneal injection of warm tulip volatile oil 200mg/kg of scalded localized oedema has an obvious inhibitory effect, intraperitoneal injection of 100m/kg of the ear caused by the oil of the croton has an obvious inhibitory effect, rats intraperitoneal injection of volatile oil 75mg/kg/day, the rat has a significant inhibitory effect on the inflammation. 75mg/kg/day, 9 days after the subcutaneous cotton ball granuloma proliferation has a significant inhibitory effect.
11. In vivo process: 3H-curcumol oral absorption is rapid and complete, rats can be measured in the blood 5 minutes after instillation of the product, 15 minutes to reach the peak, can be maintained for about l hours, half-life t1/2. for 33 minutes, t1/2? for 12.5 hours. Distribution in vivo to the liver, kidney concentration is the highest, for other tissues 2-2.5 times, and can be through the blood-brain barrier, mainly from the urinary excretion, bile is also excreted. There is a phenomenon of hepatic-intestinal circulation.