1. The packaging container is broken, the label is unclear, the expiration date is exceeded or the liquid is turbid. 2. After the packaging container is opened, the vaccine should be used up within 1 hour. 3. Before and after using this vaccine, it must be separated from other live vaccines or immunoglobulins for more than 2 weeks. 4. Don't take it with hot water, so as not to affect the immune effect of the vaccine. 5. This vaccine is an oral vaccine, and injection is strictly prohibited. 6. This product is a live vaccine, and it is not recommended to use it in the epidemic season. 7. Drugs such as adrenaline should be available in case of emergency to prevent serious allergic reactions. Those who take the seedlings should observe them on the spot for at least 30 minutes after taking them.