1, when treating megaloblastic anemia, we usually need to supplement 15-30mg folic acid every day, and use it with vitamin B 12.

2. When treating hyperhomocysteinemia, taking 0.8mg folic acid every day can effectively reduce the concentration of homocysteine in blood and keep it at a normal level.

3, pregnant women or pregnant women in order to prevent fetal neural tube malformation, generally take 0.4mg a day. It is also beneficial for men to take folic acid, which can improve sperm quality. Therefore, both men and women can take folic acid together three months in advance, and they will have healthy and smart babies!

Folic acid is a water-soluble vitamin, and its molecular formula is C 19H 19N7O6. It is named after the rich content of green leaves, also known as pteroyl glutamic acid. There are several forms in nature, and its parent compound is composed of pteridine, p-aminobenzoic acid and glutamic acid.

Folic acid contains 1 one or more glutamyl groups, and most of the naturally occurring folic acid is polyglutamic acid. The bioactive form of folic acid is tetrahydrofolic acid. Folic acid is yellow crystal, slightly soluble in water, but its sodium salt is very soluble in water. Insoluble in ethanol. It is easy to destroy in acidic solution, unstable to heat, easy to lose at room temperature, and easy to be destroyed by light.

Folic acid has two ways of active absorption and diffusion passive absorption in the body, and the absorption site is mainly in the upper part of the small intestine. The absorption rate of reduced folic acid is higher, and the more glutamyl groups, the lower the absorption rate. Glucose and vitamin C can promote absorption.

The absorbed folic acid exists in intestinal wall, liver, bone marrow and other tissues in vivo, and is reduced to tetrahydrofolate (THFA or FH4) with physiological activity by folic acid reductase with the participation of NADPH, which participates in the synthesis of purine and pyrimidine.

Therefore, folic acid plays an important role in protein synthesis, cell division and growth, and promotes the formation of normal red blood cells. When lacking, it can reduce hemoglobin production in red blood cells and hinder cell maturation, leading to megaloblastic anemia. ?

The above contents refer to Baidu Encyclopedia-Folic Acid.