Calcium gluconate can reduce capillary permeability, increase capillary wall compactness, reduce exudation, has anti-inflammatory, repercussive and antiallergic effects, and can be used for urticaria, exudative edema and pruritic dermatosis. Intravenous injection can cause systemic fever; Too fast calcium salt injection will excite the heart, cause arrhythmia and even cardiac arrest [1].

Calcium gluconate has strong anti-allergic effect and few side effects, which is commonly used in clinic, but it is also easy to cause adverse reactions in the process of treating allergies. Therefore, clinical use of any drugs should be cautious, especially those that may cause allergic reactions. Ask the patient's medication history and allergy history in detail before taking the medicine, whether it is fasting (fasting is easy to cause adverse reactions); Nurses pay close attention to patients' consciousness and complaints during medication, find adverse reactions as soon as possible, and inform doctors to deal with them in time; Try to take supine position for intravenous drugs; Please take a rest (about 20 minutes) after taking the medicine, especially for outpatients, and pay attention to observing and asking patients to find the occurrence of adverse reactions as soon as possible.