This mainly depends on the severity and nature of primary lung disease. If acute pulmonary embolism leads to pulmonary heart disease in patients, then active thrombolysis and anticoagulation should be given to acute pulmonary embolism. In addition, for the standardized control of heart failure, this situation may live with the disease for a long time, or it may achieve clinical cure, which will not affect the life span of patients.

However, some diseases, such as cor pulmonale caused by chronic obstructive pulmonary disease, may obviously limit the life span and quality of life of patients. Acute heart failure may worsen at any time, leading to the death of patients.

In addition, like other diseases, pulmonary fibrosis and pulmonary heart disease caused by lung tumors, the primary lung disease itself is incurable in clinic, and there is no good solution, so it can only be treated symptomatically.

The patient's cor pulmonale will gradually develop. To a certain extent, acute heart failure and malignant arrhythmia may occur, resulting in the death of patients, and the possibility of living for five years is 50%.