Usage and dosage: oral: decocted, 15-30g, with a large dose of 60g；; Or mash the juice. External use: tamping. 1, enhancing immune function
In vitro tests show that the antibacterial potency of this product is very low, but the anti-infection effect is obvious after oral administration. By stimulating the reticuloendothelial system, the phagocytosis of white blood cells is increased and the bactericidal power of serum is improved. The phagocytosis of Congo red by leukocytes in the administration group was 4 times higher than that in the control group. Microscopic examination showed that reticuloendothelial system proliferated obviously, reticular cells proliferated and hypertrophy, cytoplasm was abundant, phagocytosis was active, and silver-loving substances in lymph nodes, spleen, liver and other tissues became denser, indicating that the body's defense function was strengthened. It can enhance the humoral immune function and significantly increase the number of hemolytic plaques in the spleen of mice.
2. Anti-tumor effect Hedyotis diffusa has inhibitory effect on leukemia cells such as acute myeloid leukemia cells and acute lymphoblastic leukemia cells in vivo; Hedyotis diffusa can inhibit and kill ascites hepatoma cells in mice. 1 mg Hedyotis diffusa can kill all ascites liver cancer cells in 24 hours with 0.2 ml. In vivo, Hedyotis diffusa has inhibitory effects on 256 wacker's cancer in rats, cervical cancer in mice 14, sarcoma in mice 180, solid liver cancer and Ehrlich ascites carcinoma with ascites converted to subcutaneous. Hedyotis diffusa can significantly inhibit the mitotic phase of mouse sarcoma 180 cells and cause tumor tissue necrosis. Triterpenoid acids have effects on lymphosarcoma 1 ascites type, cervical cancer 14, liver cancer solid type, sarcoma 180, coumarin has effects on cervical cancer 14, sarcoma 180 and liver cancer solid type, and polysaccharide has effects on lymphosarcoma 1 80. Therefore, in the sarcoma 180 mice treated by Hedyotis diffusa, in addition to inhibiting tumor cells, there are also lymphocytes, neutrophil infiltration, lymph node, spleen reticuloendothelial cell proliferation and liver lymph node formation, and Kuhn's cells proliferate and hypertrophy obviously.
3. Inhibition of spermatogenesis This product can inhibit the development of mouse spermatogonia to primary spermatocytes and the formation of cavities in seminiferous tubules. Clinical research also showed that the number of sperm in the subjects decreased significantly after taking the product orally for 3 weeks.
4. Anti-snake venom effect The water extract of this product can reduce the mortality of mice poisoned by bungarus multicinctus. (Toxicity: the lethal dose of the extract is 50%, and the intraperitoneal injection in mice is 104g crude drug /kg. ) 1. Treatment of children's pneumonia: Hedyotis diffusa injection, 2ml intramuscular injection each time (containing 4g of crude drug active ingredient), halved for infants, twice a day for 5-7 days as a course of treatment. After treatment 1 12 cases, 52 cases were cured, 25 cases were basically cured, 7 cases were improved 12 cases were ineffective, 6 cases died, and the average hospitalization time was 7.98 days.
2. Treatment of appendicitis: Take 50 grams of fresh Hedyotis diffusa (25 grams of dry product) and decoct it in water twice a day. Children should be reduced. Severe symptoms can be increased to 2 ~ 3 levels. Individual patients with severe abdominal distension were treated with water needle or new needle, and those with severe poisoning symptoms were treated with rehydration and fasting. 19 cases were all cured, including acute appendicitis 12 cases and appendix abscess in 3 cases. Fever decreased in 8-9 days, with an average of 1.9 days and 3.3 days. Symptoms and signs disappeared in 3.2 days and 6 days respectively. 1 case recurred after 4 months of cure and was still cured by the same method. It is reported that 200 grams of fresh whole grass (50 ~ 100 grams of dry product) is used, and 1 ~ 2 doses are decocted daily; Or make 100% injection for intramuscular injection, 2ml each time, twice a day, and 6 hours/kloc-0 in severe cases. Treating more than 50 cases of appendicitis (including acute appendicitis, subacute appendicitis and appendicitis complicated with peritonitis). Generally, the clinical symptoms disappeared within 2-3 days after taking the medicine, and she was discharged after 1 week. Acute appendicitis is the best. The curative effect of decoction is better than that of injection. It is also reported that 30 cases of acute and chronic appendicitis were treated with decoction orally. For simple patients with mild symptoms, Hedyotis diffusa was used only 1 ~ 2 days after onset. For those with severe symptoms and obvious systemic and local symptoms, Lygodium japonicum, Flos Chrysanthemi Indici or Eucalyptus leaves can be used together. Except for 2 cases of chronic appendicitis who were admitted to hospital for operation again, they all recovered and were discharged. The average hospitalization time was 4.2 days.
3. Treatment of paraepididymal stasis after vasectomy: On the basis of common spermatic cord occlusion and traditional Chinese and western medicine treatment, adding Hedyotis diffusa (decocting twice a day for 1, usually 3-4 weeks is a course of treatment, and the longest time exceeds 10 weeks) can improve the curative effect; Especially for simplicity.
The influence of epididymal stagnation is more obvious. Can be used for treating testicular swelling's pain caused by excessive heat and toxic substances. Hedyotis diffusa has the functions of clearing away heat and toxic materials, softening and resolving hard mass. Prescription: Hedyotis diffusa 20g, Cortex Phellodendri 15g, Radix Scrophulariae 15g, Radix Rehmanniae 15g, Fructus Forsythiae 15g, Flos Carthami 10g, Rhizoma Sparganii 12g and Achyranthes bidentata/kloc-0. Decoct with water, one dose a day.
4. Treatment of snake bite: Take this product 5 yuan, boil it with half a catty of Chinese liquor for 3-5 minutes, remove the residue, take it orally for 2/3 times (1 2-3 times a day), and apply it externally to the wound. When applying medicine, the poisonous blood of the wound should be sucked out first, then covered with sterile cotton pad after cleaning and disinfection, and then the dressing should be moistened with medicated wine (to keep it moist). If you can't drink, you can boil it with clear water, and then add a proper amount of white wine after boiling, but it is generally better to cook it with white wine. For patients with persistent edema, serious illness and wound infection, other Chinese herbal medicines and antibiotics should be added appropriately; For mild to moderate cases, this method can be used alone. According to the observation of 19 cases, it is generally cured after taking 3 ~ 6 doses.
5. Treatment of pelvic inflammatory disease and adnexitis: Hedyotis diffusa 75g, Ardisia japonica 15g. (Zanthoxylum nitidum) or Dioscorea nipponica Makino 15g. (Eucommia ulmoides. ) decoction, 65438 0 doses per day. Of the 77 patients, 4 were ineffective and the rest were cured.
In addition, 100% Hedyotis diffusa injection was injected intramuscularly, 2ml each time, three times a day, to treat cervical cancer, gastric cancer and liver cancer 1 case, and the symptoms were improved to varying degrees. Hedyotis diffusa, Herba Artemisiae Scopariae and Herba Lysimachiae Christinae each 50% treated cholelithiasis and other biliary diseases 10 cases, among which 9 cases were relieved of abdominal pain, jaundice and fever, with an average of 2.2 days. After choledocholithotomy in 3 cases, the bile volume doubled, a large number of bile sediments were discharged, and the jaundice index gradually decreased, suggesting that Lidan mixture has obvious gallbladder-promoting and stone-removing effects.
6, treatment of gastritis: 50 grams of Hedyotis diffusa, Rhizoma Corydalis 10 grams, 250 ~ 300 ml of water, decoction for 30 minutes, twice for each dose, three times before meals, 20 days for 1 course of treatment. The effect of treating superficial gastritis is better.
7. Treatment of hepatitis: Hedyotis diffusa, Radix Salviae Miltiorrhizae and Radix Isatidis have remarkable curative effects on acute icteric hepatitis. Decocting Herba Hedyotidis Diffusae, Herba Lysimachiae Christinae, and Herba Leonuri with water to remove residues and extract juice, the curative effect of treating acute viral hepatitis is satisfactory. Hedyotis diffusa, lalang grass rhizome, salvia miltiorrhiza and codonopsis pilosula should be taken with water after meals. After taking several doses, stop taking the drug for 2-3 days, and then take it again, with appropriate addition and subtraction, which is also effective in treating acute viral hepatitis. In particular, it should be reminded that the dosage and administration method of all parties should be strictly in accordance with the doctor's advice.
8. Treatment of benign thyroid nodules: Hedyotis diffusa 30g, Radix Paeoniae Rubra 15g, Radix Platycodi 6g, and brown sugar 10g, which have good effects after long-term administration.
9. Treatment of acne: Hedyotis diffusa 20-30g, Ophiopogon japonicus, Radix Rehmanniae 15-20g, Radix Scrophulariae 1 0-5g, daily1dosage, decocted in water twice, * * * 500ml, taken twice, and the residue can be. Avoid using cosmetics and other drugs during treatment.
10. Treatment of intractable vulvar eczema: 30g of Hedyotis diffusa, 30g of Rhizoma Atractylodis, 30g of Rhizoma Smilacis Glabrae, 20g of Folium Artemisiae Argyi (below), 0/500ml of water/kloc-0 ~15min, and decocting with slow fire for 20min, waiting for filtrate.
1 1, excessive liver fire can be decocted with 20 grams of Hedyotis diffusa.