1, excessive uric acid production. This may be due to diseases, such as leukemia, chronic nephropathy, multiple osteomas, etc., which lead to excessive uric acid formation, or it may be due to the lack of enzymes that metabolize purine, and uric acid will also increase with age.

2, uric acid excretion decreased. Abnormal renal function in dealing with uric acid may lead to decreased uric acid excretion. 90% of patients with persistent high uric acid have abnormal renal function in dealing with uric acid, including inhibition of renal tubular secretion, increased renal tubular reabsorption and decreased glomerular filtration.

3. Poor eating habits. If patients drink too much, overeat, often eat barbecues, drink polysaccharide drinks, and eat foods with high purine, it will lead to the inability of the body to excrete purine, and then the uric acid value will increase.

Please note that the above is only general information, and the specific reasons may vary from individual to individual. If you have any health concerns, it is recommended to consult a professional doctor or obtain accurate information from authoritative sources.