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Medicinal value of radix aucklandiae
Sexual taste: spicy and pungent; Bitter; Sexual temperature.

1 classic: Xin Wen. 2 "Herbal Soup": hot in gas, bitter in taste and non-toxic.

Meridian tropism: spleen tropism; Large intestine and triple energizer meridian.

① Herbal supplement: dredging the liver meridian. ② Description of Medicinal Properties of Leigong's Processed Drugs: Entering the Six Meridians of Heart, Lung, Liver, Spleen, Stomach and Bladder. Efficacy: promoting qi circulation and relieving pain, invigorating spleen and promoting digestion.

Indications: promoting qi circulation and relieving pain; Adjust the middle and guide the lag. The main cell is swollen and satisfied; Abdominal pain; Vomiting and diarrhea; Severe after dysentery. For chest pain, diarrhea, dyspepsia, loss of appetite; Unconscious qi; Sudden deafness; Snakes and insects bite; Toothache.

1. Abdominal distension or pain, belching, nausea and vomiting caused by qi stagnation of spleen and stomach.

2. Damp-heat and turbidity hinder chest tightness and abdominal distension, and loose stool suffers from anorexia.

3. Cough and asthma caused by phlegm-dampness choking the lungs.

4. evil spirits, poisonous epidemics, warm ghosts, strong will, and the main dew. Long-term use does not dream. (classic)

5. Disinfection, killing ghost essence, warm malaria poison, deficiency of qi, cold in tendons, essence of medicine. ("Don't record")

Administration and dosage: oral: decoction,1.5 ~ 9g; The pill powder is halved.

Contraindications: use with caution for people with yin deficiency and body fluid deficiency.

1. Classic of Materia Medica: Be careful not to commit lung deficiency and heat. Internal heat due to yin deficiency and body deficiency, fever due to various diseases, heartburn due to fire, etc. are prohibited.

2. "Ying Bencao": The viscera are hot and dry, and those with insufficient stomach qi should not be used. 1. "Medicine Elephant": Radix Aucklandiae, in addition to qi stagnation and lung stagnation, must use betel nut to treat middle-jiao and lower-jiao.

2. "Herbal Soup": woody, "Jing" cloud, the main qi is insufficient, and it is also supplemented; Ventilation guides the qi and breaks it; An fetus strengthens the spleen and stomach, and supplements it; Except scabies, it's broken. What's the difference with this article? Yi Lao thinks that the medicine that breaks qi can't be replenished.

3. Zhu Zhenheng: Aucklandia is used for air conditioning. Its taste is pungent, the circulation of qi can rise, and if the qi is depressed, it is appropriate. If the yin fire rushes up, it will encourage the fire evil. Use Cortex Phellodendri and Rhizoma Anemarrhenae instead of Radix Aucklandiae.

4. "Compendium of Materia Medica": woody, make up for it, and vent it.

5. "Outline": Radix Aucklandiae is the medicine of triple energizer, which can lift qi. All qi stagnation belongs to the lung, so the qi stagnation of the upper jiao is also released today; The middle qi is not transported and belongs to the spleen, so the middle jiao qi stagnates and the spleen and stomach like incense. Qi stagnation in large intestine is severe, qi stagnation in bladder is stranguria, and stagnation of liver qi is painful. Therefore, qi stagnation in the lower jiao is appropriate, which is also helpful for obstruction.

6. Materia Medica: Radix Aucklandiae, the general medicine for treating qi in herbal medicine, regulates stomach qi, clears heart qi, lowers lung qi, soothes liver qi, accelerates temper, warms kidney qi, disperses qi, warms cold, goes against qi, reaches exterior qi, clears interior qi, controls qi inside and outside the body, and pushes its merits alone. However, it is fragrant, dry and fierce, such as lung deficiency with heat, blood dryness with impetuous pulse, yin deficiency with fire, heartburn with fire, gas collapse, latent heat of various diseases, etc., so we should pay attention to it.

7. "Drug meaning": woody incense can dredge the five internal organs and is a medicine for regulating qi. Can be used for treating fullness, edema, abdominal distension, dysentery, and beriberi, all of which can regulate depression and disperse qi. But the spicy incense returns to the yang, and the yang rises and floats. If the middle coke and the lower coke stagnate, the betel nut will definitely fall. Because of its dryness, Coptidis Rhizoma and Scutellariae Radix are used for dysentery, Cortex Phellodendri for beriberi and cold medicine for dryness, so Shen Si is used. If anger blows back and hurts the whole body to regulate lung qi, lung qi will be self-sufficient; If the liver qi stagnates, it will cause pain between the ribs and the lower abdomen, and the liver qi will flow, so that the blood will be smooth and the pain will stop.

8. "New Edition of Materia Medica": Radix Aucklandiae acts as an assistant to stop qi circulation, but it cannot be said that it can replenish qi and reuse it. Use about 1 cent and 2 cents to 1 dollar, and never exceed 1 dollar. Too much won't work. Tonifying is not tonic, and assisting is not diarrhea.

9. "Hundred Records of Materia Medica": Mugen wins with qi, so his merits and demerits all care about qi. In Neijing, the cloud heart dominates the smell, and all drugs with strong qi enter the heart. If the wood is fragrant but does not disperse, the qi can be vented, so it can also pass its qi to the small intestine.

10. "Seeking Truth from Materia Medica": Radix Aucklandiae has a wide range of qi, which is the key medicine for triple energizer. However, the triple energizer focuses on the middle. So all spleen and stomach deficiency and cold stagnate, but stop eating when you see vomiting and diarrhea; When the liver is deficient and cold, but the qi is depressed and the qi is reversed, taking this bitter fragrance can reduce the qi and stomach. It is an important agent for coking delay in the third coking plant. According to the book, it can rise and fall, disperse and make up. It is not the kind of firewood in Yun Sheng, but agarwood. However, because it is depressed, it can reach the ear. What's more, it's more than enough, not enough. It's okay to say it, but it's not enough. Leave it alone and let the books mix. It's none of its business.

1 1. Herbal justice: wood is fragrant and thick, and the classics end in pungent, so don't record it as warm. Although the knot bone is called strong smell, it should be the main sink, but its gas is rich, and the medicine is so blind, then the smell of cooking is inevitable. Wang Haizang said that diligence and heat, taste is thicker than gas, while yang is in yin, and he agreed. Classic against evil spirits, evil spirits are eliminated. Pathogens can be fragrant, and plagues are harmful. They are nothing more than haze and stench, which is strong enough for patients and can eliminate foul gas. Strong will and fragrant gas are enough to shake the spirit. Dew dripping is due to the sinking of Qingyang and the rising temperature of woody plants, so it can be cured. If the heat accumulates in the lower part, it is not appropriate. Treating warm malaria means eliminating dampness and evil spirits. Failure to cure deficiency of qi will promote yang and help healthy qi. Medical practitioners, qi is more handsome than blood, and can guide the ear as various drugs. The main purpose of lakeside medicine is the same. Radix Aucklandiae treats things with qi, so it is especially suitable for treating various pains caused by qi stagnation, especially for cold pain. However, although hard temperature is different from big heat, people who are depressed by anger and fire must also use it to dissipate depression, but not too much. Those with bitter taste will be dry, and those with yin deficiency are best considered. If you use too much, it will consume fluid and hurt the yin, and the gas will become more and more chaotic, and the pain will not be solved. Close to it is used for tonic, and it is useless if you are tired of nourishing. Coupled with this, it will make it run quickly and digest healthily, and it is also a good way to assist. Hernia stagnation in the lower intestine is an essential drug.

12. Classic: Dominate evil spirits, dispel poisonous epidemics, strengthen ambitions, and dominate exposure.

13. "Bielu": Treating evil qi and cold in tendons. Main qi deficiency, disinfection, warm malaria, essence of medicine.

14. Notes on Materia Medica: Treating swelling and toxin and eliminating pathogenic factors.

15. theory of medicinal properties: treat women's blood, qi, stabbing pain and heartache, and finally take it with wine. Treat nine kinds of heartache, cold accumulation, anorexia and bloating pain, and dispel all kinds of suffocation and boredom. Treat cholera, vomiting and diarrhea, and stab the heart.

16. daily chemical herbs: treat qi in the hearts, stop diarrhea, cholera, dysentery, prevent miscarriage, strengthen the spleen and promote digestion. Treat inferior, bladder cold pain, vomiting and nausea.

17. Wang: Treat the pulse, and rush inward against the qi. Mainly because of exudation and constipation.

18. Herbal Xuan Tong: Managing hernia. 1. Treatment of qi disharmony and pain: grind wood roots with warm water and thicken them with hot wine. ("purely unilateral")

2. Treatment of abdominal pain caused by internal fishing: five points for each of Radix Aucklandiae, Olibanum and Myrrh. Take it with water. (Ruan Xiaoerfang)

3. The fullness of stool caused by air attack is difficult to treat: Radix Aucklandiae 150g Fructus Aurantii 100g (parched with bran to remove pith), Sichuan rhubarb 200g (lightly parched with file), and Petunia peel 150g. Mash the medicine into honey and mash it. ("Sheng Huifang" Muxiang Pill)

4. Unconsciousness in the middle of treatment, closing your eyes and saying nothing is like a stroke: inverted 10g. Wax gourd seeds with woody soup. Add bamboo juice and ginger juice to those with phlegm. (Compendium of Materia Medica is quoted from Huo Fang)

5. Treatment of qi stagnation in stomach: 50 grams of radix aucklandiae, 50 grams of pepper, 50 grams of dried ginger (crushed), 50 grams of wax powder of Shangsanwei, 50 grams of Wutong pills and seven pills of warm wine. (Muxiang Pill, Total Record of Shengji)

6. Treat abdominal distension quickly and widely: radix aucklandiae, morning glory (fried) and betel nut, etc. The last drop pills, such as Tongzida, take ginger and radish soup after 30 pills. ("Healthy Simple Prescription")

Medication guidance

Radix Aucklandiae is the root of Radix Aucklandiae of Compositae. Aucklandia is produced in Lijiang, China. Aucklandia is mainly produced in Anxian County and Liangshan Yi Autonomous Prefecture of Aba Tibetan Autonomous Prefecture in Sichuan. Auckland used to be imported from India, Myanmar and other places via Guangzhou, so it is called "Auckland". Digging in autumn and winter, removing sediment and fibrous roots, cutting into sections, vertically cutting into petals, and knocking off rough skin after drying. It's better to have a strong aroma. Raw or stewed.

Muxianggen is cylindrical and semi-cylindrical, with a length of 5~ 15cm and a diameter of 0.5~5.5cm, and its surface is yellowish brown or grayish brown. Most of the cork has been removed, with obvious longitudinal grooves and root marks. It is solid and heavy, and is not easy to break. Its cross section is grayish yellow, scattered in dark brown oil chambers, brown cambium ring, radial texture, withered old roots in the center, strong and specific fragrance and bitter taste. It is best to be compact, even, fragrant and oily. Root oil mainly contains dehydrocostunolide and costunolide, with the content of 50% [1 2], and also contains Saussurea aldehyde and 4β- methoxydehydrocostunolide [2]. Costunolide, dihydrocostunolide) [3] 3], α-cyclocostunolide, β-cyclocostunolide, Inulin, isoalantolactone [4], Isodehydrocostunolide, IsozaLuzanin C [5], 12- methoxydihydrocostunolide (12-).

Roots also contain 20 amino acids (a, b, c, d, e, L- masson pine resin) such as storax, glutamic acid, glycine, asparagine, asparagine, asparagine, citrulline, γ-aminobutyric acid, cholamine [1 1] and Saussurea involucrata.

Effects of Taraxacum Sterol, α-geraniol Stearate, β-geraniol Palmitate and Lupeol Palmitate in Leaves on Respiratory System: The experiment of isolated trachea and lung perfusion in guinea pigs showed that the extracts of Aquilaria Resinatum, ethanol, volatile oil and total alkaloids had antagonistic effects on histamine and acetylcholine. The total lactone, costunolide, dihydrocostunolide and other lactone components contained in the volatile oil, as well as the volatile oil without lactone, can resist the bronchoconstriction caused by histamine, acetylcholine and barium chloride, among which dihydrocostunolide has a stronger effect. Intraperitoneal injection can protect guinea pigs from inhaling lethal dose of histamine or acetylcholine aerosol, prolong the incubation period of asthma and reduce the mortality. The above results show that the characteristics of smooth bronchiectasis are similar to papaverine. It is believed that the direct action is caused by smooth muscle. The intrathoracic intubation was inserted into the pleural cavity of anesthetized cats to record breathing, and bronchiectasis could occur after intravenous injection of aucklandia. However, it is ineffective after brain injury, suggesting that its effect is related to central inhibition of vagus nerve. Water extract, alcohol extract, volatile oil, lactone-free volatile oil and total alkaloids have certain inhibitory effects on breathing in anesthetized dogs. Among them, the volatile oil has a strong effect, and the lactone component contained in the volatile oil has no obvious effect on respiration. Cough induced by mechanical stimulation in dogs proves that lactone components and lactone-free volatile oil in volatile oil have no antitussive effect.

Effect on intestine: Aquilaria Resinatum extract, volatile oil and total alkaloids have slight excitation on isolated small intestine of mice, and then the tension and rhythm are obviously reduced. It can antagonize intestinal muscle spasm caused by acetylcholine, histamine and barium chloride. The effect of small dose decoction on isolated small intestine is irregular, while large dose decoction has inhibitory effect. Volatile oil can also inhibit the movement of isolated rabbit small intestine, making its rhythm slow and its contraction irregular. Ketone volatile oil, total lactone, costunolide and dihydrocostunolide volatile oil have strong effects on dihydrocostunolide.

Cardiovascular effects: Low concentration of volatile oil of Radix Aucklandiae and various lactones separated from the volatile oil have different degrees of inhibitory effects on the activities of isolated hearts of guinea pigs and rabbits, and also have inhibitory effects on isolated frog hearts.

Small doses of water extract and alcohol extract have exciting effects on frog heart and dog heart in vivo, while large doses have inhibitory effects. Intravenous injection of aucklandia 1-2mg can excite the heart of cats in vivo, and its effect on ventricle is more obvious than that on atrium. The vascular perfusion experiments of isolated rabbit ears and hind limbs of rats also showed that the volatile oil and total lactone of lactone had obvious vasodilation effect. Other lactones have little effect. Low dose of total alkaloids can dilate isolated rabbit ear blood vessels, while high dose can cause contraction reaction.

Intravenous injection of water extract and alcohol extract has mild pressor reaction in anesthetized dogs. Intravenous injection of anti-lactone volatile oil, total lactone, costunolide, dihydrocostunolide and dehydrocostunolide can moderately reduce blood pressure (30-40mmHg) in anesthetized dogs, and the antihypertensive effect is relatively lasting. Cutting the cervical spinal cord and bilateral vagus nerves, atropinizing or giving ganglion blockers, adrenergic drugs or antihistamines did not change the above antihypertensive reactions. It is preliminarily believed that the hypotensive mechanism is caused by cardiac inhibition and vasodilation.

Antibacterial effect: the concentration of volatile oil 1:3000 has inhibitory effect on streptococcus, staphylococcus aureus and staphylococcus albus, but has little effect on Escherichia coli and diphtheria; Total alkaloids have no antibacterial effect. The decoction has a slight inhibitory effect on Bacillus paratyphi, but it has no effect on seven pathogenic bacteria such as Staphylococcus aureus and Shigella dysenteriae. It is also reported that the decoction has inhibitory effect on 10 kinds of fungi, such as Vicia faba and its Mongolian variety.

Pharmacology: The lethal dose of intraperitoneal injection in rats is: total lactone 300mg/kg and dihydrocostunolide 200mg/kg. The maximum tolerated dose of total alkaloids by intravenous injection is 65438 000 mg/kg in mice and 90mg/kg in rats. The volatile oil was mixed into the feed of rats, and the daily dose was 1.77mg/kg (male rats) and 2. 17mg/kg (female rats) for 90 days. The results showed that the growth, blood routine and blood urea nitrogen of rats were not affected, and the pathological examination of main organs was normal.