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What are the causes of low platelets?

1. Abnormalities or diseases of the immune system

Abnormalities or diseases of the immune system lead to the inability of the immune system to recognize platelets and attack them as foreign bodies, causing massive destruction of platelets, resulting in Low platelets. Some immune diseases such as HIV and systemic lupus erythematosus can also destroy a large number of platelets, causing low platelets.

2. Reduced platelet production

Reduced platelet production is clinically common in various blood system diseases, such as aplastic anemia. Aplastic anemia has many causes. The bone marrow hematopoietic failure syndrome caused by thrombocytopenia causing bleeding in various organs is one of the important characteristics of this disease. In addition, leukemia can also cause low platelets. In addition, the bone marrow suppression period after radiotherapy and chemotherapy for other blood diseases can also Causes low platelets.

3. Hypersplenism

Hypersplenism causes platelets to remain in the spleen, causing low platelets in the blood.

4. Drug factors

Many drugs can also cause low platelets, mainly including the following categories:

1. Antipyretic and analgesic drugs: common There are aspirin, anti-inflammatory pain, etc.

2. Hypnosis, anticonvulsants: Diazepam, phenobarbital, etc.

3. Antibiotics: penicillin, erythromycin, cephalosporins.

4. Other drugs such as digoxin, tetanus toxoid, etc. may cause low platelets.

In addition, excessive consumption of platelets can also lead to low platelets. For example, thrombus caused by disseminated intravascular coagulation will significantly reduce platelets in the blood.

Under normal circumstances, platelets are evenly distributed in blood vessels. When the human body is injured and bleeding, platelets will quickly move to the wound and form soft hemostatic emboli. These emboli can promote blood coagulation and repair the wound; Therefore, when the body's platelets are low, the wound will be slow to stop bleeding.