There are many ways to lower aminotransferases, but you can't blindly use enzyme-lowering means to achieve the effect of lowering aminotransferases. It must be diagnosed according to the patient's physical qualities, as well as the condition and type of disease, and the best treatment program and medication must be chosen in order to achieve the goal of a complete cure.
1. The main drugs used for the treatment of high ghrelin are traditional Chinese medicines and their active ingredient extracts. The above Chinese medicine components have the effect of benefiting the liver and kidney, detoxification and elimination of dampness, and can be used to treat various chronic liver diseases with high transaminase. As long as the patients use the enzyme-reducing medicines correctly, most of the transaminase can be effectively controlled, and the enzyme-reducing therapeutic effect is long-lasting and stable. And, the Chinese medicine enzyme reduction in the discontinuation of rebound control is much better than Western medicine.
2. The treatment of high ghd straighteners is only a symptomatic treatment, so, while protecting the liver and reducing the enzyme, it is necessary to take measures for the cause of the disease to "treat the root cause". For example, the treatment of high aminotransferase caused by hepatitis B, enzyme lowering at the same time must be antiviral and immune adjustment therapy, both symptoms and root causes in order to achieve the ultimate therapeutic purpose.
Don't blindly use drugs to reduce transaminase, while reducing the enzyme first look at what causes high transaminase.
High transaminases are not always hepatitis. Elevated transaminases can only be used as a reference indicator of liver damage. Factors that cause elevated transaminases are very common.
Generally speaking, high transaminases caused by extrahepatic lesions are mostly mildly elevated; if the serum transaminase value exceeds the upper limit of normal (40 units) by 2.5 times and lasts for more than half a month, the possibility of hepatobiliary diseases is high; if the measurement result exceeds the upper limit of normal by 20 times, it can be basically concluded that it is caused by hepatobiliary diseases and is mainly due to hepatocellular injury, but it can by no means be arbitrarily concluded that it is Hepatitis. This is because what we call hepatitis usually refers to viral hepatitis caused by hepatophilic viruses, including A, B, C, D, E and other types. Liver abscesses, liver fluke, liver cysts, liver tuberculosis, and alcoholic liver disease caused by bacteria, parasites, or alcoholism can also cause liver damage and elevated transaminases. In addition, aminotransferase is excreted into the small intestine through the biliary system. When biliary obstruction is caused by various reasons, the excretion of aminotransferase is bound to be affected, and the aminotransferase in the blood will be elevated, which is mainly seen in cholelithiasis, biliary roundworms, periampullary carcinoma, and carcinoma of the head of the pancreas. If you can confirm the diagnosis of transaminase elevation disease, the treatment of transaminase elevation at the same time for the treatment of the primary disease, in order to play the effect of both symptoms and root causes.
There are many different reasons for elevated aminotransferases, and in order to solve the problem of chronically high aminotransferases, it is necessary to find out the reasons first, and then to prescribe the right medicine.
①The liver itself, especially the various types of viral hepatitis, liver cirrhosis, liver abscess, liver tuberculosis, liver cancer, fatty liver, etc., can cause varying degrees of transaminase elevation.
②In addition to the liver, the body's other organs and tissues such as the heart, kidneys, lungs, brain, testicles, muscle also contain this enzyme
③Because the transaminase is excreted from the bile ducts, so if the bile ducts, the gallbladder and pancreatic disorders, the bile ducts are blocked, can also make the transaminase increased.
④Pharmacological or toxic liver damage
⑤Normal pregnancy, pregnancy toxicity, acute fatty liver in pregnancy are also common causes of transaminase elevation. In addition, strenuous exercise can also cause transaminase elevation. Chronic aminotransferase elevation is a special temporary clinical diagnosis, but also many non-viral hepatitis, liver disease patients the only clinical manifestations, most of the history, physical examination and a series of laboratory tests can determine the cause of liver disease; however, there are still some liver function abnormalities can not be interpreted through routine examination, which requires further histological examination of liver penetration, to clarify the cause of the disease. Only when the cause of elevated aminotransferases is clear which of the above conditions is the cause, can the root cause be traced back to the source and the right medicine be prescribed. The high aminotransferase in clinical examination is relatively common, caused by high aminotransferase has many reasons, some of these reasons are non-pathological as well as pathological, for non-pathological reasons caused by high aminotransferase, generally do not need to use drugs; and part of the pathology caused by high aminotransferase can be lowered enzyme treatment.
Enzyme-lowering drugs
1, schizandra and biphenyl dibenzoate
Schizandra and biphenyl dibenzoate can enhance the detoxification function of the liver, and the enzyme-lowering effect is strong and fast. Taking 2-3 weeks of 90% of the ghrelin can be decreased, 80% back to normal, but stopping the drug half a month -3 months can rise again. And the dose can be reduced. Adults use tablets 1-2 tablets each time, 3 times a day, drops 6-10 capsules. If the aminotransferases return to normal, the dosage can be reduced and continued for 3-6 months to prevent rebound. The drug has fewer side effects, occasionally nausea, epigastric discomfort, insomnia.
2. Yilianling
It has the ability to reduce enzymes, improve liver metabolism, and stabilize the function of liver cells. It has an enzyme-lowering efficiency of 67.2%, and can also improve appetite, reduce fatigue and swelling. The dosage is 4 pills 3 times a day. There are also compound liver spirit in China, the efficacy is better than the former, 3 daily, each time 3-4 tablets.
The former used to protect the liver to reduce enzyme drugs, in the end, high transaminase to eat what medicine? Director Jiang pointed out that patients with high aminotransferase first to find the cause of the disease, symptomatic treatment, in order to play a good therapeutic effect:
1. Temporary aminotransferase high, such as strenuous exercise, overfatigue, taking some drugs such as erythromycin, sleeping pills, antipyretic and analgesic drugs, etc. will cause temporary aminotransferase high, in these cases you can not have to take medication to remove the cause of the disease and then go to the hospital for examination, the aminotransferase will be
2. Malnutrition, dietary structure is not reasonable can cause high transaminase, then eat more high protein food, adjust the diet, transaminase will soon return to normal;
3. other causes of high transaminase what to take drugs? This aspect is the most important and common cause of high transaminase, such as liver disease, bile duct obstruction, typhoid fever, autoimmune diseases. Also, it is possible for a healthy person to have transaminase levels that are temporarily outside the normal range. Because transaminases are very sensitive, they can fluctuate at different times of the day in healthy people. Therefore, high transaminase levels do not necessarily require medication. If the transaminases are elevated due to these conditions, enzyme-lowering treatment is usually not necessary. If you rest well and take a checkup after some time, you will find that your aminotransferase level has returned to normal. Commonly used Chinese medicinal preparations
Chinese medicinal preparations have an obvious protective effect on liver cells, which can reduce inflammation and cell degeneration, lower the vitality of aminotransferases in liver cells, resist liver cell necrosis, and promote liver cell regeneration. Chinese medicine enzyme-lowering preparations are more varied, mainly including schizandra preparations, Yam bean root preparations, licorice preparations, oleanolic acid preparations, silymarin preparations, Taraxacum officinale preparations and so on, *** with the same characteristics is to reduce serum aminotransferase speed is very fast, the effect of the treatment is immediate, almost all have no obvious toxic side effects, can be used for a long time, and the price is very cheap, is absolutely suitable for the majority of the people to use. The disadvantage is that it can only be used as an auxiliary drug for the treatment of hepatitis, and its enzyme-lowering effect is outstanding, but the antiviral effect is still unsatisfactory. Therefore, they also belong to the "symptoms" of the product, "cure" is still missing fire.
1. Biphenyl dibenzoate: this drug is synthetic Schizandra chinensis, has the ability to promote liver cell regeneration, increase liver detoxification, promote the generation of hepatic glucose, and protection of mitochondria, lysosomes, reduce the speed of the fastest speed of aminotransferases. It is mainly used for chronic prolonged hepatitis and should not be used for acute or severe hepatitis. It is used as bifidobacterium drops, 5~10 capsules (7.5~15μg) per oral dose, 3 times a day, for 3 months, and then gradually reduce the dosage. Bifidobacterium tablets are 1~2 tablets (25~50μg) per oral dose, 3 times daily, 6 months as a course of treatment.
2. Strongly Ning: This drug is a mixture of glycyrrhizic acid monoamine and levulinic amino acid, which has anti-inflammatory, anti-allergic, inhibition of immune response and anti-fibrotic effects, as well as inducing interferon generation. Thus, it reduces patients' transaminase level, improves symptoms and reduces the level of jaundice, but has no significant effect on the clearance of hepatitis virus. Usage is 60~100ml once a day added to 5% or 10% glucose injection 250~500ml in intravenous drip, 1~3 have for a course of treatment.
3. Ganlixin: Ganlixin mainly contains glycyrrhetinic acid diamine, which is an improved product of Qiangguonin, with better enzyme-lowering effect than Qianglixin, and less adverse effects than Qianglixin. Usage: 30ml per day, diluted drip. Oral is 450mg per day, divided into 3 times, precautions are the same as strong nin.
4. Silymarin: This product is a new type of flavonoid glycoside extracted from the seeds of artichoke, which has strong hepatoprotective effect. It can restore the function of liver cells, reduce steatosis, and inhibit the increase of ghrelin. It is used in the treatment of acute and chronic hepatitis, early cirrhosis and toxic hepatitis. Silymarin Glucosamine Tablets, 50mg/tablet, 200mg per day, to be taken orally in 2 times. Compound Liver Ling Tablets (Compound Silymarin Tablets) containing silymarin and schizandra, 2 tablets/dose, 3 times/day.
5. Fructus schisandrae preparations: have anti-free radical effect, can stabilize the liver cell membrane, inhibit the release of aminotransferases in the mitochondria, and promote the regeneration of liver cells. Single-flavored Schisandra has an enzyme-lowering effect, but it is easy to rebound after stopping the drug.
6. Xiao Chaihu Tang preparation: this preparation is used in hepatitis treatment has several aspects of the role. In addition to lowering enzymes, it can promote hepatocyte regeneration, induce endogenous interferon, enhance macrophage vitality and natural killer cell vitality, thus inhibiting and eliminating hepatitis virus.
7. Qingkailing: It is a compound injection modified from Angong Niuhuang Pill, which has many effects such as clearing heat, detoxifying, calming and tranquilizing the mind. In addition, it has a repair effect on damaged liver cells. It can also reduce the enzyme and reduce the yellow color, which is suitable for acute hepatitis and subacute severe hepatitis, and the effect of intravenous drip is better than that of intramuscular injection.
Other: with the enzyme lowering effect of Chinese herbal preparations also include Taraxacum officinale, Dandelion, Salvia miltiorrhiza, Tianji Huang, Yunzhi polysaccharide, poria mushroom polysaccharide, Lycium barbarum polysaccharide, Scutellaria baicalensis glycosides, etc., all have good results. It is important to note that the use of medication must follow the doctor's instructions, usually choose one or two single or combined treatment can be, so as not to increase the burden on the liver.