Current market common treatment of vitiligo methods:
1, hormone therapy: including systemic treatment and localized treatment. Systemic treatment is the use of oral or intramuscular injection of hormones, can quickly stabilize the progression of vitiligo, so it is suitable for generalized progressive vitiligo patients. Local treatment is to apply topical glucocorticosteroids such as mometasone furoate cream and halometasone ointment to the damaged area, which can effectively treat limited vitiligo, but long-term use may cause adverse reactions. Therefore, it is suitable for short-term treatment of limited vitiligo.
2, phototherapy and photochemotherapy: phototherapy is the treatment through light, whether it is the treatment of limited or generalized vitiligo, have a good effect. The specific method is through narrow wave ultraviolet irradiation of the damaged parts, can promote melanin deposition, to achieve the effect of treatment. Photochemotherapy (PUVA) is the use of local topical application of furan coumarin drugs such as tincture of psoralen, 8-MOP, etc. and assisted by sunlight irradiation, can effectively treat limited vitiligo, this method is suitable for children over 5 years old and adults.
3, transplantation therapy: for the stable phase, the skin damage time is not long and the damage site is not infected, the patient has no scar. Commonly used methods include autologous epidermal transplantation, stamp skin piece transplantation, allogeneic skin transplantation, autologous culture melanocyte transplantation and so on.
4, drug therapy, including immunosuppressant therapy, vitamin D3 derivatives combined with other drugs. Immunosuppressants are mainly calcineurin phosphate inhibitors such as pimecrolimus. This method can effectively treat vitiligo without the use of hormones, and can avoid the harm of long-term use of hormones. Vitamin D3 derivatives combined with other medications, such as NB-UVB, PUVA, or combined with topical hormones and calcium-modulated nerve phosphatase inhibitors.