Find out the cause of the disease, remove the factors that cause the disease, is the way to cure the disease. However, the cause of urticaria, especially chronic urticaria is often difficult to find, so most cases are often symptomatic treatment. Some can not remove the disease should reduce a variety of triggering factors, especially in physical urticaria. Care should also be taken to avoid factors that aggravate skin vasodilatation. Can be given

1. Antihistamine drugs: the main h1 receptor antagonist and h2 receptor antagonist, a variety of antihistamines antihistamine effect in the degree of each other is different, and they have other pharmacological effects of each other there are also differences; such as cold urticaria with cyproheptadine effect is good, hot urticaria with antalerta efficacy is significant, stubborn urticaria can be a combination of the application of h1 and h2 receptor antagonist, to improve the efficacy of h1 and h2 receptor antagonist. h1 and h2 receptor antagonists can be combined to improve the efficacy.

2. Adrenocorticotropic hormone: for acute severe or persistent cases, such as anaphylaxis, serum sickness urticaria, pressure urticaria, etc. can be used hydrocortisone 100-200mg added to 5% dextrose solution in intravenous drip, or prednisone 30-40mg oral, this treatment is generally not suitable for long-term application.

3. Antibiotics: the infection caused by the appropriate antibiotics, especially for the gastrointestinal tract has obvious or latent infection caused by urticaria.

4. Reduce the permeability of the blood vessel wall drugs: such as vitamin C, vitamin P, calcium. Often used with antihistamines.

5. Sympathomimetic drugs: mainly used in severe acute urticaria, especially with anaphylaxis or laryngeal edema. Apply 0.1% epinephrine 0.5~1 ml subcutaneous injection, severe cases can be injected again every 20~30 minutes.

6. Histamine globulin: it is a drug that prompts the body to produce anti-histamine antibodies, which is more effective in chronic urticaria, especially in mechanical and cold urticaria. Each 2~4 ml intramuscular injection, 1~2 times a week, 6~8 times for a course of treatment.

7. Other: can choose vitamin k, vitamin e, vitamin b12, aminophylline, lisdexamfetamine, chloroquine and so on orally, inhibit peptidase, 6 aminos have, sodium thiosulfate static point, heart and tissue therapy, autologous blood therapy and so on.

8. Local treatment: can be used externally to appease the itch medicine.