If the drug is not symptomatic, it will lead to the aggravation of leukoplakia. If used for a long time, it may cause certain damage to liver and kidney function and aggravate the condition. On the contrary, it will produce drug resistance and drug resistance, destroy the skin structure and blood microcirculation structure in the white spot area, thus delaying the disease.
The treatment of vitiligo includes drug therapy, surgical treatment and phototherapy (such as narrow-band UVB and 308 excimer laser). ) and so on. Under normal circumstances, patients need to choose appropriate treatment methods under the guidance of doctors, combined with their own causes and conditions.
1. Drug therapy: Glucocorticoids are commonly used, such as fluticasone propionate and mometasone furoate; Calcineurin inhibitors, such as tacrolimus ointment and pimecrolimus cream; Vitamin d? Derivatives, such as carbatriol ointment, tacalcitol ointment, etc. , can restore some skin color, improve appearance, and avoid the continuous spread of white spots.
2. Surgical treatment: For patients who have no new leukoplakia in the past 12 months, or whose leukoplakia has not worsened in the past 12 months, or whose leukoplakia is not caused by skin injury such as severe sunburn, transplantation treatment can be selected.
3. Narrow-band UVB: Narrow-band UVB phototherapy stimulates the skin to produce photochemical reactions or regulate the immune system, stimulates the human immune ability and regulates the immune function of keratinocytes, thereby inhibiting inflammatory reactions, promoting the growth of melanin and regenerating melanocytes.
4.308 Excimer Laser: It refers to the use of 308 nm excimer laser therapeutic instrument, which directly acts on the part of leukoplakia, promotes T cell apoptosis, activates tyrosinase, restores the growth of melanocytes, and achieves the purpose of treatment.