Motor neuron disease (MND) is a group of chronic progressive neurodegenerative diseases with unknown etiology, which selectively invades spinal cord anterior horn cells, brain stem motor neurons, cortical pyramidal cells and pyramidal tract. The onset of motor neuron disease is slow, and the course of disease can be subacute. Symptoms depend on the location of the early injury. Most of the earliest symptoms appeared in the hands. The patient feels that his fingers are weak, stiff and clumsy, and his hand muscles are gradually atrophied, and muscle bundle tremor can be seen. If the early lesion is located in the motor nucleus of the medulla oblongata, there will be difficulty in pronunciation and swallowing, tongue muscles will be paralyzed and atrophied, and muscle bundles will tremble on the surface of the tongue. For example, early pathological bilateral pyramidal tract and spastic paraplegia of both lower limbs can appear first. Motor neuron diseases include amyotrophic lateral sclerosis, progressive spinal muscular atrophy, progressive bulbar palsy and primary lateral sclerosis.

The main causes of motor neuron disease are dryness and heat impairing body fluid, liver and kidney yin deficiency, spleen and kidney yin deficiency, essence and blood deficiency and other factors. Although Su Wen Wei Lun points out that "burning leaves due to lung heat" is the main cause of flaccidity syndrome, the onset of this disease is slow. Even if you suffer from leukoplakia of spinal cord or have a history of metal contact in the past, it has been many years, which is caused by unknown pathogenic heat and burning body fluids after illness.

Syndrome differentiation and classification

Injury of lung heat and body fluid: weakness of limbs, muscular atrophy, dry mouth, dry skin, red urine, red tongue with yellow coating and rapid pulse. Clearing heat and moistening dryness, promoting fluid production;

Damp-heat immersion: weakness of limbs, fatigue, chest tightness and fullness, red tongue with yellow and greasy coating, and rapid pulse. Treatment is to clear away heat and dry dampness, dredge channels and activate collaterals;

Yin deficiency of liver and kidney: numbness and weakness of limbs, backache, dizziness, red tongue with little coating and rapid pulse. Treatment is to nourish liver and kidney and replenish essence;

Qi deficiency of spleen and stomach: weakness of limbs, loss of appetite, shortness of breath, abdominal distension, dull complexion, pale tongue with thin coating and thready pulse. Strengthening spleen and benefiting qi;

Yang deficiency of spleen and kidney: aversion to cold in limbs, muscle weakness, abdominal distension, loose stool, pale tongue with thin white fur, and deep and thin pulse. Treating with warming kidney and strengthening spleen;

Stagnant pulse: numbness and weakness of limbs, or blue veins or pain, dull tongue with petechiae, and dull and astringent pulse. Nourishing and treating with qi, promoting blood circulation and removing blood stasis;

I believe that everyone knows something after reading these, and must be treated in time after getting sick.