Sea snakes are sea treasures.

Like terrestrial snakes, sea snakes also have high economic value. Its skin can be used to make musical instruments and handicrafts; its meat and eggs are edible and delicious, and some of its internal organs can be used as medicine.

The use of snakes as medicine is recorded in "Shen Nong's Materia Medica": sea snakes are used as medicine, which was first recorded in "Supplementary Materials of Materia Medica" written by Chen Zangqi in the Tang Dynasty. It is mainly used for red and white poisonous dysentery, five pheasant diseases, malignant sores, moxibustion, and also after burning.

1. People along the coast have the habit of eating sea snakes. It is also widely used medicinally as a good medicine for dispelling wind and dampness, unblocking collaterals and activating blood circulation, attacking poison and nourishing and strengthening. It is often used for rheumatic paralysis, numbness of limbs, joint pain, and scabies.

Malignant sores and other symptoms.

Dried sea snakes The Fujian Provincial Institute of Traditional Chinese Medicine made a comparative analysis of the chemical composition of sea snakes such as the Green Sea Snake, the Long-nosed Sea Snake, and the Sea Viper, and the land snakes such as the Agkistrodon striata and the Golden White Snake. It was found that the nitrogen content of sea snakes is as high as 9.94%, which is more than that of land snakes.

1.03%, the fat content is 0.53% higher than that of land snakes, and the total amino acid content is 5.2% higher than that of land snakes. Among them, the essential amino acids lysine, threonine, leucine, and isoleucine for the human body are higher than those of land snakes.

More than 16%.

It also proves that the original sea snake medicine is safe to use and non-toxic.

Zhou Shaoxiong et al. studied the nutritional components of the ethanol extracts of four common sea snakes, including the Green Sea Snake, and found that it contains 19 kinds of amino acids, with arginine, glutamic acid, valine and lysine having higher contents, and 8-1

It is rich in trace elements such as oxidized lysine, Zn, Cu, and Fe, and macroelements such as Ca, K, and Na.

Preparations developed with sea snake bodies as the main raw materials include compound sea snake capsules from Shanghai Shikangte Pharmaceutical Co., Ltd., compound sea snake capsules developed by Shanghai Huadong Hospital, sea snake Qufengshengshi Capsules from Quanzhou Pharmaceutical Factory, compound sea snake tincture and

Compound Sea Snake Injection developed by Guangxi Beihai People's Hospital, etc.

The main raw materials of the compound sea snake capsule developed by Huadong Hospital are South China Sea snake and jade foot ginseng, which can improve microcirculation, promote immune function, enhance memory and other effects. Quanzhou Pharmaceutical Factory's sea snake Qufengshengshi capsule is composed of sea snake, Sichuan Wu and Corydalis chinensis.

It is refined from ginseng, Qianghuo, angelica, licorice, etc. It has the functions of replenishing qi and nourishing blood, dispelling wind and dampness, unblocking meridians, and strengthening muscles and bones.

The main raw materials of the Compound Sea Snake Injection developed by Beihai People's Hospital of Guangxi are Qinghuan Sea Snake, Flat-chinned Sea Snake, Angelica sinensis, black bean ginger, etc. It is used for rheumatoid arthritis, low back and leg pain and other paralysis diseases.

The compound sea snake tincture of Zhanjiang Traditional Chinese Medicine Factory has obvious anti-inflammatory and analgesic effects. In addition, the Traditional Chinese Medicine Research Institute of Fujian Medicinal Materials Company has developed sea snake gastrodia elata wine.

Sea urchin Traditional medicine believes that snake gall has the functions of promoting qi and reducing phlegm, removing wind and dampness, clearing the liver and improving eyesight, and is used to treat coughs, asthma and other diseases.

Cai Yunjian et al. measured that the pure extract of sea snake gall contains 36.5% taurocholic acid. Calculated as fresh bile, it contains 0.34% taurocholic acid, which is equivalent to land snakes such as cobra, bungara, and bungara.

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Animal experiments show that sea snake gall has significant antitussive and expectorant effects, and can significantly alleviate tracheospasm caused by acetylcholine.

Therefore, sea snake gall can be used for respiratory diseases such as cough and asthma just like land snake gall.

Sea snake oil Coastal fishermen often boil sea snake oil for external use on water and fire burns, frostbite, insect bites, etc.

Research shows that sea snake lipids and lipidoids contain a variety of saturated unsaturated fatty acids, among which palmitic acid, hexadecenoic acid, octadecenoic acid, eicosenoic acid, etc. are relatively high in content, and docosahexaenoic acid is

(DHA), eicosapentaenoic acid (EPA), vitamin A, vitamin D3, vitamin E, etc. are also very rich in content. There is a kind of oil acupuncture therapy in Japan. Injections made of sea snake lipids as the main raw material are applied to tender points and

Injections into induration sites can treat low back pain and pain in jaws, shoulders and other parts of the body. Sea snake lipids are also made into soft capsules and used as health care products to enhance learning and memory functions and prevent osteoporosis.

Sea snake venom is very toxic, far more toxic than land venomous snakes. Usually the LD50 of pure sea snake venom is less than 0.10mg/kg, such as the common green-ringed sea snake, 0.05mg/kg, and the flat-chinned sea snake, 0.06mg/kg.

Sea snake venom is similar to land snake venom in that it is also a mixture of proteins.

The main components are neurotoxins and various enzyme proteins.

The neurotoxin isolated from sea snake venom mainly acts on the postsynaptic a neurotoxin. It binds to the nicotinic acetylcholine receptor at the motor end plate of skeletal muscle and blocks the neuromuscular junction transmission of skeletal muscle. Therefore, the risk of poisoning is

Muscle paralysis occurs in humans and animals, and respiratory muscle paralysis often leads to death by suffocation. Sea snake venom does not contain cardiotoxin and has no direct effect on the heart.

However, there is obvious striated muscle toxicity, and the muscle damage caused is clinically manifested by the occurrence of hemoglobinuria. It is generally believed that it is not neurotoxins that cause muscle damage, but phospholipase A. Thrombolytic and hemostatic products were developed using terrestrial snake toxin as the main raw material.

Analgesic and other preparations. The development and utilization of sea snake toxins is relatively lagging behind. One of the reasons is that the amount of toxin excreted by sea snakes is relatively low and it is difficult to collect a sufficient amount of venom for application. There are much fewer domestic and foreign research reports on sea snake toxins than terrestrial snake toxins.

In recent years, domestic research has made new breakthroughs. Sun Yat-sen University and others have established multiple sea snake venom gland expression libraries and cloned dozens of new sea snake gene sequences.