1, drug introduction
Puerarin injection can be used for adjuvant treatment of coronary heart disease, angina pectoris, myocardial infarction, retinal arteriovenous occlusion and sudden deafness. However, although puerarin injection is effective, a few patients may have allergic reactions such as rash, allergic asthma, anaphylactic shock and fever. Very few patients may have hemolytic reaction. Once the above adverse reactions occur, the drug should be stopped immediately and symptomatic treatment should be given. Puerarin injection has a good effect, but it should be noted that some patients may have problems when using it, so patients with serious organic diseases such as severe liver and renal insufficiency and heart failure are prohibited.
Matters needing attention
1. Use with caution for those with bleeding tendency.
2. Puerarin injection may be crystallized out after long-term storage at low temperature (below 65438 00℃). At this time, the ampoule can be placed in warm water and can still be used after the crystal is dissolved.
3. People with insufficient blood volume should use this product after replenishing blood volume in a short time.
4. For diabetic patients, this product should be diluted with normal saline and then injected intravenously.
5. Users of this product should regularly monitor bilirubin, reticulocyte, hemoglobin and urine routine.
6. Those who have symptoms such as chills, fever, jaundice, low back pain, and deepening urine color need to stop taking drugs immediately and treat them in time.
Step 2 explain
Efficacy Indications can be used for the adjuvant treatment of coronary heart disease, angina pectoris, myocardial infarction, retinal arteriovenous occlusion, sudden deafness, ischemic cerebrovascular disease, viral myocarditis in children, diabetes, etc. Patients with coronary heart disease can also take quick-acting jiuxin pills, and the effect is also good.
Administration and dosage: intravenous drip: 0.4 ~ 0.6g/ time, daily 1 time, 15 days as a course of treatment.
Adverse reactions A few patients have temporary abdominal distension, nausea and other reactions at the beginning of medication, which can disappear automatically after continuing medication; Very few patients have allergic phenomena such as rash and fever after taking the medicine, and can return to normal after stopping taking the medicine immediately or symptomatic treatment.
Patients with serious organic diseases such as severe liver and kidney damage and heart failure are prohibited; Use with caution for those with bleeding tendency.
Pharmacological action This product is a flavonoid glycoside extracted from pueraria lobata or its roots in Leguminosae. Animal experiments show that (1) has effects on smooth muscle. Many flavonoids in pueraria lobata can relax smooth muscle, and their contractile components may be choline, acetylcholine and cathinone R.
(2) Effect on body temperature: The rabbit ears were artificially heated by intravenous injection of expired typhoid vaccine. After oral administration of 20% pueraria decoction or 20% ethanol infusion, the body temperature drops, especially after infusion.
(3) Effect on cardiovascular system Pueraria lobata has certain antihypertensive effect on normal and hypertensive animals. Total flavonoids of pueraria lobata and puerarin have obvious coronary artery dilating effect, which can dilate normal and spasmodic coronary arteries. After intravenous injection of 30mg/kg, coronary blood flow increased by 40% and vascular resistance decreased by 29%.