High uric acid is the chief culprit of gout, but some people think gout is immortal, so they choose to "cook it". As a doctor who specializes in gout, I want to remind you that the influence of high uric acid on the body is not only gout, but also serious diseases, such as renal failure, diabetes, cardiovascular and cerebrovascular diseases and so on. Don't ignore it. I'd like to share it with you. In uric acid is too high for a long time, the body will generally have that kind of performance.

1, joint pain, swelling Many uric acid crystals are deposited in the joint capsule, which can cause gouty rheumatism. Patients usually have sudden joint pain in the middle of the night, which is as painful as being stabbed. In severe cases, it will endanger walking, accompanied by swelling of bones and joints, and some skin temperatures will rise. The first metatarsophalangeal joint (the joint between toe and foot) is the most common, accounting for about 90%, and knee joint, kneecap, elbow joint and interphalangeal joint are also involved.

2, tophus If the blood uric acid is not well controlled, gout continues to develop, and many uric acid crystals are deposited in subcutaneous tissue and joint capsule, which will produce tophus, leading to bone and joint hyperplasia, destruction and deformity. Once tophi happens, the blood uric acid in the body is already very high.

3. Sudden oliguria or anuria of uric acid crystals deposited in renal function can lead to acute and diffuse uric acid nephropathy and urolithiasis. Many uric acid crystals are deposited in renal tubular injury, which leads to subacute urinary tract obstruction and sudden symptoms such as oliguria, anuria and subacute chronic renal failure. So once this happens, you need to be careful of uric acid is too high. /kloc-patients with hyperuricemia in 0/0 ~ 20 years, due to the long-term deposition of crystals between kidneys, lead to diffuse interstitial nephritis, which can appear frequent urination at night, decreased urine specific gravity and mild to moderate proteinuria, which is the main manifestation of diffuse uric acid nephropathy.

4. Abnormal high blood sugar level Uric acid will reduce the body's utilization of glucose water, endanger the extraordinary performance of insulin glargine, make urate crystal damage islet cells, and will continue to reduce the body's sensitivity to auntie, leading to an increase in blood sugar level, thus enhancing the risk of patients with ll type diabetes.

5. Abnormal increase of blood pressure If the blood uric acid level in the body is too high, it will lead to the loss of capillary contraction function. High uric acid level can stimulate the platelet function in blood night, which will lead to an increase in blood pressure.