It can reduce and prevent the reaction of tissues to inflammation, thus reducing the manifestations of inflammation. Hormones inhibit the aggregation and phagocytosis of inflammatory cells (including macrophages and leukocytes), the release of lysosomal enzymes and the synthesis and release of inflammatory chemical mediators.
Extended data
Dexamethasone is not usually used as an alternative treatment for adrenocortical hypofunction because of its weak sodium retention effect. Dexamethasone sodium phosphate has high permeability, long action time and the same pharmacodynamics as dexamethasone, but it is easily soluble in water and can be made into water-soluble preparations, which expands the route of administration and application.
Long-term heavy use may show signs of hypercortisolism, and it is necessary to observe blood sugar, blood pressure and whether there are mental symptoms. Effects of drugs on children: Dexamethasone is a long-acting preparation, which is generally not used for children who need long-term use of hormones.
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