Severe allergies often appear in the skin test or injection within 10 minutes. The patient first felt chest tightness, shivering to convulsions, dizziness, headache, dyspnea, cyanosis, pallor, cold hands and feet, blood pressure dropped suddenly, the pulse is fast and weak, such as rescue is not in time, often due to respiratory and circulatory failure and death on the emergence of a serious allergic reaction to the patient should be immediately injected subcutaneously or intravenously with 0 l% epinephrine 0.5-1ml. The use of acupuncture therapy, acupuncture Renzhong, Neiguan and other points. According to the condition, after ten minutes, 0.1% epinephrine 0.3-0.5 ml can be injected again. If there are conditions, intravenous infusion should be made, and 5% glucose or electrosaline should be input, and 100-200 mg of hydrocortisone can be added into the liquid, and for those whose blood pressure falls sharply, pressure-raising drugs such as alamine or norepinephrine should be added into the infusion. Oxygen inhalation can be given if possible. Desensitizing drugs such as fenugreek (ipecac) 25 mg are used, as well as other methods of symptomatic treatment. When the scene is no infusion conditions, can be given to the intravenous injection of 25% dextrose 60-80 ml, intravenous injection of drugs to raise blood pressure, but the speed of pushing the drug should be slow, such as the lack of static injection conditions, can also be injected into the muscle alamine. Penicillin allergy occurs although the situation is rapid, but as long as the treatment is appropriate, the patient's recovery and prognosis are better, and this emergency measures (mainly such as intramuscular injection of epinephrine), in the rural grass-roots medical units can also be used. Such as forcing severe anaphylactic shock patients, urgent transfer to the hospital, then do not deal with, often on the way to the emergence of a variety of dangerous situations.