if you only make koji medicine for the distillery and don't make wine yourself, you need to apply for a production license for agricultural and sideline products. Daqu belongs to enzyme preparation, which is the role of catalyst, and the final result is that it is completely changed into something else. The additive is that the result still exists and will not be transformed. If you make your own wine, you only need to apply for the relevant license for the wine, but you don't need to apply for the license for koji medicine.