Cnidium monnieri, also known as wild carrot seed, is the dried and mature fruit of Cnidium monnieri (L.) Cuss., an umbelliferous plant. Harvest the fruits when they are mature in summer and autumn, remove impurities and dry them in the sun. Nature and flavor: Warm in nature, pungent and bitter in taste. Functions and Indications: Warming the kidneys and strengthening yang, drying dampness, dispelling wind, and killing insects. It is used for impotence, uterine cold, cold-damp vaginal discharge, dampness and lumbago; external treatment of vulvar eczema, gynecological pruritus, and trichomonal vaginitis.

Edit this paragraph introduction

Fructus Cnidii (English) Common Cnidium Fruit Harvesting and Processing The fruits are harvested from July to August when they are mature and sun-dried. Characteristics: The double-hanging fruit is small and oval, 2-4mm long and about 2mm in diameter. The surface is gray-yellow or gray-brown, with two outward-curved plinths at the top and occasional thin stems at the base. There are 5 thin and protruding longitudinal ridges on the back of the hanging fruit petal, the joint surface is flat, and there are 2 brown slightly protruding longitudinal ridge lines. The peel is crispy; the seeds are small, gray-brown, and oily. It smells fragrant, tastes pungent and cool, and has a numbing sensation on the tongue. Chemical ingredients include pinene, bornyl isovalarate, osthol, dihydrocentol, berapten, cnidiadin, and isoanisolin (isopimpinellin) etc. English name FRUCTUS CNIDII, also known as wild fennel, wild carrot seed, snake rice, snake chestnut. Characteristics: This product is a double-hanging fruit, oval in shape, 2 to 4 mm long, and about 2 mm in diameter. The surface is gray-yellow or gray-brown, with two outward-curved plinths at the top and occasional thin stems at the base. There are 5 thin and protruding longitudinal ridges on the back of the spores, the joint surface is flat, and there are 2 brown slightly protruding longitudinal ridges. The peel is crispy and easy to fall off when rubbed. The seeds are small, grey-brown and oily. It smells fragrant, tastes pungent and cool, and has a numbing sensation on the tongue. The nature and flavor are acrid, bitter and warm; slightly toxic. Returns to kidney meridian. Functions: Warming the kidneys and strengthening yang, drying dampness, dispelling wind, and killing insects. It is used for impotence, uterine cold, cold-dampness, lower back pain due to dampness; external treatment of vulvar eczema, vaginal itching in women; trichomonal vaginitis. Contraindications for use: Those with damp and heat in the lower burner, insufficient kidney yin, easy movement of phase fire, or weak Jing Guan should not take it. ① "Compendium of Materia Medica": "Peony, Croton, Fritillaria." ② "Compendium of Materia Medica": "Do not take it if there is fire in the kidneys or heat in the lower part." ③ "Ben Jing Feng Yuan": "Kidney fire is easy to move. , do not take it if the yang is strong and the essence is not stable." Dosage: 3 to 9g. Appropriate amount for external use, decoction for fumigation and washing, or grind into powder for application. Store in dry place.

Edit this section for identification

(1) Cross section of the fruit of this product: the exocarp is a row of flat cells and is covered with cuticle. The mesocarp is thicker, with abnormally protruding longitudinal ribs. There are vascular bundles in the middle and thick-walled lignified reticulated cells around it. There is 1 oval oil tube between the longitudinal edges on the back, 2 oil tubes on the joint surface, and 6 in total. indivual. The endocarp is composed of 1 row of flat cells. The seed coat is a row of light brown cells. The endosperm cells contain many aleurone grains, and each aleurone grain contains small clusters of calcium oxalate. (2) Take 2g of this product powder, add 20ml of ethanol, heat to reflux for 30 minutes, and filter. Take a few drops of the filtrate, place it on a white porcelain plate, observe under a UV lamp (365nm), and see blue-purple fluorescence; take another 2 ml of the filtrate, add an equal amount of 3% sodium carbonate solution, heat for 5 minutes, let cool, and then Add 1 to 2 drops of newly prepared diazo-p-nitroaniline test solution, and it will appear cherry red. (3) Take 0.3g of this product's coarse powder, add 5ml of ethanol, ultrasonicate for 5 minutes, leave it aside, and take the supernatant as the test solution. Take another osthole reference substance, add ethanol to make a solution containing 1mg per 1ml, and use it as the reference substance solution. According to the thin layer chromatography (Appendix VI B) test, draw 2 μl of each of the above two solutions, and place them on the same silica gel G thin layer plate with sodium carboxymethylcellulose as the binder, and use benzene-ethyl acetate (30 :1) Use a developing agent, unfold it, take it out, dry it, and inspect it under a UV lamp (365nm). In the chromatogram of the test product, fluorescent spots of the same color appear at the positions corresponding to the chromatogram of the reference substance.

Edit this paragraph content determination

Precisely weigh 1g of the powder of this product (passed through No. 3 sieve) that has been dried under reduced pressure in a phosphorus pentoxide dryer to a constant weight, and place it in a utensil Precisely add 20 ml of ethanol into a stoppered Erlenmeyer flask, shake and leave overnight, filter, and take the remaining filtrate as the test solution. In addition, take an appropriate amount of osthole reference substance, weigh it accurately, add ethanol to make a solution containing 1mg per 1ml, and use it as the reference solution. According to the thin layer chromatography (Appendix VI B) test, accurately draw 1 μl of each of the above two solutions, place them at the intersection points on the same silica gel G thin layer plate, use benzene-ethyl acetate (30:1) as the developing agent, and develop. Remove and let dry. Carry out fluorescence scanning according to thin layer chromatography (Appendix VI B thin layer scanning method), excitation wavelength: λ = 365nm, measure the integrated value of fluorescence intensity of the test sample and the reference substance, and calculate it. This product contains osthole (C15H16O3) not less than 1.0%.

Edit this section Plant form

Annual herb, 30-80cm tall. The stem is upright, branched, with longitudinal grooves on its surface and sparsely pubescent hairs. The leaves are alternate, with 2 to 3 pinnulate lobes, the final lobes are linear-lanceolate, and the apex is sharp; the basal leaves have long stalks, and the base of the stalk expands into a sheath shape. Compound umbels terminal or axillary; involucral bracts 8 to 10, linear; flowers white, style base short conical, style slender, reflexed. The double-hanging fruit is broadly oval, with winged edges. The flowering period is from April to July, and the fruiting period is from June to August. Born in moist places such as wilderness, fields, roadsides, and creeksides. Mainly produced in Hebei, Zhejiang, Jiangsu and Sichuan. Excerpt from "Chinese Pharmacopoeia"

Edit this paragraph Pharmacological effects

Original form

Anti-trichomoniasis effects

Cnidium monnieri external therapeutic drops in traditional Chinese medicine Parasitic vaginitis, but the effect of a single flavor of Cnidium monnieri is poor or very weak, and its active ingredients have not been reported. Compound Cnidium suppositories or lotions are very effective.

Sex hormone-like effects

Cnidium monnieri ethanol extract, subcutaneously injected into mice every day for 32 consecutive days, can prolong the estrous period, shorten the interestrus period, and cause the appearance of estrus in castrated mice. During estrus, the weight of the ovaries and uterus increases, which has similar sex hormone-like effects. The method of increasing the weight of the prostate, seminal vesicles, and levator ani muscles (mice) proves that Cnidium monnieri extract has androgenic hormone-like effects. It has no corrosive effect on rabbit vaginal mucosa.

Antiasthmatic effect

3.1. The total coumarins in Cnidoma monnieri have anti-asthmatic effects, which can significantly reduce or eliminate wheezing in the lungs of asthmatic patients, significantly increase the peak expiratory flow rate, and improve lung ventilation function. Its effect is to expand bronchial smooth muscle and improve pulmonary ventilation function. It is speculated that the total coumarins of Cnidium monnieri may have the effect of B-receptor agonists, and its antiasthmatic effect may be through activation of the regulatory subunit (B-receptor) of adenylyl cyclase on smooth muscles and cell membranes. Increase intracellular cAMP, leading to phosphorylation of proteins in intracellular storage sites, uptake of Ca2+, and Ca2+ entering a combined state. As a result, intracellular free Ca2+ decreases, the excitability of the smooth muscle contractile protein system decreases, and muscle relaxation is achieved. 3.2. The total coumarins in Cnidium monnieri also have a certain expectorant effect. 3.3. The total coumarins from Cnidoma monnieri have a significant protective effect on experimental asthma in guinea pigs caused by inhalation of spasmodic agents. In vitro, they can relax the tracheal smooth muscle caused by histamine-induced spasm, and can enhance the pulmonary perfusion of guinea pigs. This shows that the drug has strong bronchodilator effect.

Other effects

In recent years, more research has been done on Cnidoma monnieri, and more and more pharmacological effects have been discovered. 4.1． Antifungal effect: In vitro tests of osthole, bergamot lactone, and isosaxifrage have strong activity against the trichophyton Trichophyton mentagrophytes; Zanthoxylin phenol has significant antifungal effect. 4.2. Anti-arrhythmic: The aqueous extract of Cnidium monnieri has a preventive effect on chloroform-induced ventricular fibrillation in mice, calcium chloride-induced ventricular fibrillation in rats, and ornithine-induced arrhythmia in rats. It also has anti-arrhythmic effects on the latter. There is obvious therapeutic effect. 4.3. Local anesthetic effect. The aqueous extract of Cnidium monnieri has a blocking anesthesia effect on the isolated sciatic nerve of toads; it has an infiltration anesthesia effect on guinea pigs, which can be enhanced by epinephrine hydrochloride; it has a spinal anesthesia effect on rabbits, but it has an anesthetic effect on domestic rabbits. There is no surface anesthesia in the rabbit cornea. It can also significantly extend the sleep-inducing time of sodium pentobarbital.

4.4. Anti-allergic osthole can strongly inhibit passive skin allergic reactions in mice, has a protective effect on overall histamine wheezing in guinea pigs, and can protect against the contraction of the isolated ileum of guinea pigs caused by slow-reacting substances and the Schultz- The Dzle reaction showed obvious antagonism and blocking effects, and could inhibit the degranulation of rat peritoneal mast cells. The above effects are all in a certain dose-dependent relationship. 4.5. The anti-mutagenic Cnidium monnieri aqueous extract has been tested through Ames, sister chromatid exchange in isolated cells, and chromosomal aberration and polychromatic erythrocyte micronucleus tests in living mouse bone marrow cells. It has been shown that the drug has strong anti-mutagenic effects. change effect. 4.6. Kill larvae. Put Cnidium monnieri into sewage to kill larvae.

Edit the chemical composition of traditional Chinese medicine in this paragraph

The fruit contains 1.3% volatile oil, the main components of which are pinene (l-Pine-ne), camphene (l-Camphene), and It forms Bornyl isovale-rate and Isoborneol. Also contains methoxyparsley (Ostho-le), Cnidimine (Edultin), IsoPiBrpinelline, Bergamot lactone, Dihydroo-roselol (Columbianetin) And its angelic acid ester (ColuInbianadin), acetate (o-Acetyl columbianetin); oral isovalerate, cnidiadiu (Cnidiadiu), isobutyryloxydihydrochenyl acetate. The roots contain cnidium, isosaxifrage, alloimperatorine, xanthotoxol, and imperatorine. The fruit contains about 1.3% volatile oil, the main components of which are 1-pinene (l-pinene), 1-camphene (l-camphene), bornylisovalerare and 7-methoxyparsleyol (osthole) )wait. In addition to 7-methoxyparsleyol, palmitic acid, β-sitosterol, bergapten, isopimpinellin and xanthotoxol, etc. According to reports, my country’s commercial Cnidoma monnieri fruit contains 0.20% of columbianadin, archangelicin, edultin, bergamotolide, isosaxifragein, and O-acetyl dihydroparanthin. (O-acetyl-columbianetin), dihydro-columbianetin, O-islvaleryl-columbianetin, 3'-isobutyryloxy-O-acetyldihydro-columbianetin (3 '-isobutyloxy-O-acetylcolumbianetin) and O-isobutyldihydro-acetylcolumbianetin (O-isobutylcolumbianetin, cnidiadin). The seeds contain citrin, orosclol and white angelica. Efficacy: Warms the kidneys and strengthens yang; removes dampness and kills insects; dispels wind and relieves itching

Edit this paragraph for textual research

From "Shen Nong's Materia Medica". 1. "Brief Records of Famous Doctors": Cnidium monnieri grows in Linzi River valley and fields. May fruits, dried in the shade. 2. Tao Hongjing: There are many snake beds in the fields and villages along the shortcuts. The flowers and leaves are like wild grass. 3. "Shu Materia Medica": "Illustrated Book" says that the snake bed is like small leaves of Xiongxiong, with white flowers and seeds like millet grains, yellow and white. Wetlands were born, and they are everywhere today. Those who came out of Yangzhou and Xiangzhou were good, and the seeds were collected and dried up. 4. "Ben Cao Illustration": Cnidium monnieri, born in March, seedlings three to two feet high, green leaves broken into clusters like artemisia branches, each branch has more than a hundred flower heads, knotted in the same nest, like horse celery, four or five The moon blooms with white flowers, which look like scattered water seeds, and are yellowish-brown, like millet, or even light and weak. 5. "Outline": Snake bed, snakes and snakes lie under it, so it has names such as snake bed and snake millet. Its flowers are clustered like broken rice, and its seeds are composed of two pieces, which are thin like dill seeds and also have fine edges. Any flowers that actually look like snake beds include Angelica sinensis, Ligusticum rhizome, cress, Ligusticum root, and carrot.

Family and genus classification Umbelliferae Latin name Fructus Cnidii Indications: male impotence; wet and itchy scrotum; female uterine cold infertility; cold and damp vaginal discharge; vulva itching and swelling and pain; rheumatic arthralgia; eczema and scabies

Edit this paragraph Ecological environment

Born on low hillsides, fields, roadsides, ditches, and riverside wetlands.

Edit the discussions of various experts in this paragraph

"Compendium of Materia Medica"

Cnidium monnieri has a bitter and mild taste; "Bielu" is pungent, sweet and non-toxic; details here Its smell must be both warm and dry, and yang. Therefore, the housewife suffers from swelling and pain in the vagina, and the man suffers from impotence, dampness and itching, which removes the paralyzing qi, sharpens the joints and causes malignant sores. "Bie Lu": Warming the middle and lowering the qi makes women have children with heat, and men with strong yin makes people have children. Covering it with the tongue can remove dampness, warm it and dispel cold, pungent it can moisten the kidneys, and its sweet taste can benefit the spleen, so it can cure all diseases caused by deficiency, cold and dampness in women and men. Once the cold and dampness are removed, the disease will be gone. It has the property of replenishing yang, so it can cure diseases and also has tonifying effect.

"New Compendium of Materia Medica"

Cnidium monnieri has very strange functions. It can be used to treat both internal and external diseases, but it is especially good for external treatment. If you want to take He Wan Powder, you can use it with ginseng, Qi, Gui, Di, and Cornus officinale. It is indeed beneficial. However, it is also suitable for people with cold yin and no fire. If you have yin deficiency and fire, it is not suitable to take it.

"Ben Jing Feng Yuan"

Cnidium monnieri not only helps men to strengthen their qi, but also relieves women's depression. Without a masterful understanding of the meaning of "Ben Jing", there is no way to cure it. also.

"Compendium of Materia Medica"

Cnidium monnieri is a warm and strong product, although the "Heritage Classic" calls it bitter. However, if it is mainly used to treat swelling and pain in the vagina of women and impotence and itching of the vagina in men, both of them treat cold and dampness. The kidney yang must be weak and cold water is diffuse, so it can be taken orally. Zhen Ji has said that it is poisonous. It is close to the lake and said that snakes and scorpions like to lie under it and eat its seeds. It covers the place under the wet and sweaty place where the child is born. This is due to the damp and hot air, and its poisonous quality can be known. The preparation method of Guan Lei Zhe is to soak it with thick blue juice, then mix it with raw rehmannia juice and steam it, which is just to control its dry and strong nature. Therefore, in modern medical books, it is rarely used as a medicine for oral administration. In addition, it is considered a cheap product in the market and is not prepared, but it can be used in decoctions. "Ben Jing" also says that it can remove paralyzing qi, sharpen joints, and cause epilepsy. If the medicine is dry and strong, it can naturally pass through the meridians and dredge the joints. However, if it is not cold and damp, and if it has not been controlled by law, it should be used with caution. "Ben Jing" also treats malignant sores, so it is also an external medicine. For external sores caused by dampness, heat, pain and itching, and soaked sores, it can be washed with decoction or applied as a powder. The effect is very quick, so it should not be ignored as a cheap product. Harvesting and Storage Harvest when the fruits are mature in summer and autumn. Pick the fruits and dry them in the sun; or cut off the above-ground parts and dry them in the sun, knock down the fruits, and sift or shake off impurities. Resource distribution: distributed throughout the country.

Edit this paragraph to select prescriptions

Cure yang but not enough

Cut Cuscuta chinensis, Cnidium monnieri, and Schisandra chinensis into equal parts. The top three flavors, the bottom one, honey pills are like Wuzi. Drink and take thirty pills, three times a day. ("Qianjin Prescription")

Treat leucorrhea due to cold and dampness

8 liang of Cnidium japonica, 6 liang of dogwood meat, 4 liang of Schisandra chinensis, 3 liang of Plantago seed, Cyperus rotundus Two liang (both stir-fried with vinegar), five qian for dried alumen, and five qian for blood deer glue (quenched with fire and wine). The powder is fine powder, and the yam paste is as big as Wuzi pills. Take five qian for every dry day and give it white soup. ("Fangmai Zhengzong")

Treatment of yin-cold in women

Medicinal medicine for warming yin: Cnidium monnieri, ground into powder, a little white powder, mixed with it, like jujube It's big, wrapped in cotton, and naturally warm. ("Jingui Synopsis" Cnidium monnieri powder)

Treat women's vaginal itching

One tael of Cnidium monnieri and two qian of alumen. Decoction and wash frequently. ("Bin Hu Collection of Simple Prescriptions")

Treatment of postpartum vaginal prolapse

One liter of Cnidium monnieri, wrapped in cloth and ironed, can also treat postpartum vaginal pain. ("A Thousand Golden Prescriptions")

Treatment of protruding internal organs in women

One liter of Cnidium monnieri and twenty-seven pieces of plum blossoms. Five liters of water, boil two and a half liters, wash it, and wait for ten days to pass. ("Seng Shen Ji Prescription" Cnidium Washing Recipe)

Treatment of Trichomonas Vaginitis

1. Five qian of Cnidium monnieri, decocted in water, and used for vaginal lavage. (Jiangxi "Herbal Medicine Manual") 2. Cnidium monnieri one liang, cork three qian. Suppositories (2 g in weight) are made with glycerin gelatin as the base, and one piece is placed intravaginally every day. (Inner Mongolia's "Selected Materials on New Chinese Herbal Medicine Treatment Methods")

Treatment of men's vaginal swelling and pain

Apply the powder of Cnidium monnieri and chicken yellow. ("Yonglei Jianfang")

Treat scrotal eczema

Take five coins of Cnidium monnieri and boil it in water to wash the vagina.

(Jiangxi "Handbook of Herbal Medicine")

Treatment of ringworm in children

Pound the Cnidium bed into powder and apply it with pig fat. ("Qianjin Prescription")

Treatment of malignant sores in children

Take 3 parts of Fenugreek powder, 1 part of Coptis chinensis (to remove beards), and 3 parts of Cnidium monnieri. Pound the medicine into powder. Every time, wash the sore with warm salt soup, wipe it dry, and apply oil on it. ("Sheng Hui Fang")

Treat lip sores in children

Also treat ear sores, head sores, and fistula sores: one tael of alumen (burnt ash), one tael of Cnidium monnieri two. For the end, mix it dry and put it on the sores. ("General Prescriptions for Pediatric Health")

Cure eczema

Atopic dermatitis, sumac allergy, tinea pedis: Cnidium monnieri, eucalyptus leaves, neem bark, duck's foot wood, Sophora flavescens and Kochia kochia are taken in appropriate amounts, boiled in water and soaked in water to wash the affected area twice a day. (Jiangxi "Handbook of Herbal Medicine")

Treatment of sore throat and swelling in winter months

Those who cannot prescribe the medicine: burn Cnidium monnieri in a bottle, put the mouth of the bottle in your mouth and smoke, the phlegm will come out naturally . ("Sheng Hui Fang")

Edit this section of medication contraindications

Do not take it if there is dampness and heat in the lower burner, or if the kidney yin is insufficient, the phase fire is easy to move, or the Jing Guan is not solid. 1. "Compendium of Materia Medica": Peony, Croton, Fritillaria. 2. "Compendium of Materia Medica": Do not take it if there is fire in the kidneys or heat in the lower part. 3. "Ben Jing Feng Yuan": Do not take this medicine if the kidney fire is easily moved and the yang is strong and the essence is not stable. Efficacy classification Warming medicine

Edit this paragraph Preparation method

Remove impurities, sieve to remove mud, wash and dry. 1. "Lei Gong Pao Zhi Lun": When making snake bed, you must use thick blue juice and natural juice of Baibucao root. When the two flavors are soaked together for three days, drain out the dried sun, but mix it with raw rehmannia glutinous rice juice and steam it from noon to Hai. , used daily. 2. "Rihuazi Materia Medica": Snake bed, if taken together with medicine, remove the skin and take the kernels, stir-fry slightly to kill the poison, it will not be spicy, make a soup to cleanse the disease, and it will cause diarrhea.

Edit this paragraph Identification of Raw Medicinal Materials

Character Identification

The dried fruit is oval, composed of 2 fruits, and is about 2mm long. About 1mm in diameter, grayish-yellow, with 2 outward-curved persistent flower bases at the top; the back of the spores is slightly raised, with 5 raised ridges, and the surface is flat, with 2 brown slightly raised longitudinal lines, among which There is a light colored line. The peel is crunchy. The seeds are small, grey-brown, and oily. It smells fragrant, tastes pungent, is cool and has a numbing sensation on the tongue. The ones with full particles, grayish yellow color and strong smell are better.

Microscopic identification

Cross section of schizocarp: Exocarp consists of 1 epidermal cell, which is often shrunken; it is covered with cuticle. The mesocarp is composed of several rows of parenchyma cells, interspersed with striped reticulated cells, most of which are on the inner side of the vascular column; there are 6 vittae, 2 on the joint surface, and 1 between every two fruit ribs on the back, and the vitacarp is oblong and oblong. , the tangential direction is about 110 μm. When the fruit is mature, the oil tube wall is only dark brown cuticle; the vascular bundle column is located in the middle of the fruit rib, the xylem vessel is round or polygonal, accompanied by a few fibers, and the phloem is located on both sides of the bundle column. The endocarp is composed of 1-2 rows of oblong cells, varying in length. The seed coat cells are often decadent, and there are several rows of cells in the center of the joint surface; there are small seed ridge vascular bundles. The endosperm cells contain fatty oil and aleurone grains, and the aleurone grains still contain small clusters of crystals. Powder: yellowish brown. 1. The epidermal cells of the exocarp have a quasi-square or quasi-polygonal surface, with microwave-like and deeply wavy curves on the vertical wall, a dense keratin texture on the surface, unequal stomata, and 4 accessory cells. 2. The reticulated cells are quasi-square, quasi-circular or quasi-rectangular, with slightly thicker walls, non-lignified or slightly lignified, with stripe or reticular thickening. 3. The tubing fragments are yellow-brown or dark red-brown, with some visible transverse septa and faint traces of cells on the surface. 4. The cell walls of the endocarp mosaic layer are sometimes thickened in a bead-like manner. In addition, there are endosperm cells and so on. This product is best when the seeds are plump, yellow-green in color, and have a spicy aroma when rubbed by hand. Nature and flavor: pungent; bitter; warm in nature

Edit this paragraph Chemical identification of traditional Chinese medicine

1. Take 2g of this product powder, add 20ml of ethanol, heat to reflux for 30 minutes, and filter. Take a few drops of the filtrate, put it on a white porcelain plate, observe it under a UV lamp (365nm), and it will show blue-purple fluorescence; take another 2ml of the filtrate, add an equal amount of 3% sodium carbonate solution, heat for 5 minutes, let it cool, and add fresh Add 1-2 drops of diazo-p-nitroaniline test solution and it will appear cherry red.

2. Take 0.5g of this product, add an appropriate amount of ether, heat and extract for 5 minutes, filter, concentrate the filtrate to 1 ml, add 2-3 drops of 7% hydroxylamine hydrochloride in methanol, 3 drops of 20% potassium hydroxide in ethanol, and place in a water bath Heat slightly, and after cooling, add dilute hydrochloric acid to adjust the pH to 3-4, then add 1-2 drops of 1% ferric chloride ethanol solution to make it purple. (Check coumarin) The source of the medicinal material is the fruit of the plant Cnidium of the Umbelliferae family.

Edit this section of common counterfeit products

Carrot seeds

are the dried and mature fruits of the wild carrot of the Umbelliferae family. Characters: Broadly oval, with two conjoined fruits. The surface is brownish-yellow or light greenish-brown, the back is raised, with 4 raised ridges, and a row of yellow-white barbs densely grown along the ridges, 1.5mm long. The joint of the two spores is flat and has 3 white veins. The body is light and hard, the smell is unique when rubbed, and the taste is bitter.

Celery fruit

It is the dried and mature fruit of the plant Celery of the Umbelliferae family. Characteristics: Double-hanging fruit, nearly round to oval, formed by two spores clasped together, about 1-1.5mm long, 1mm in diameter, grayish brown or gray green on the surface, elliptical in shape, slightly curved and kidney-shaped. The back is obviously raised, with 5 raised ridges, and the joint surface is small and uneven. The peel is crispy, with 1 tiny seed, kidney-shaped, with longitudinal ribs, and has a strong celery aroma when pinched by hand. It tastes pungent and cool, slightly bitter.

Rough solitaire fruit

It is the pseudo-example of the dry fruit of the rough solitaire plant of the Umbelliferae family. Character: Obovate or egg-shaped. 6-7mm long, 4-5mm wide. The surface is yellowish brown to light brown, with no style residue at the top and few style residues, but a thin fruit stalk is sometimes seen. The spores are obovate in shape, with no obvious protrusions and thin wings on the fruit ribs, and large brown oil tubes in the shape of obvious rods can be seen. There are oil tubes in each rib groove, and the oil tubes extend downward from the top of the fruit to less than the bottom of the fruit. 4~5mm long. There are oil tubes on the symbiotic noodles, and sometimes peeled carpel stalks can be seen. The peel is crispy, yellowish brown, slightly fragrant and slightly pungent.

Edit this paragraph for clinical application

Treatment of trichomonas vaginitis

First rinse the vagina with 500ml of 10% Cnidium monnieri decoction, and then put 0.5 g of Cnidium monnieri vaginal tablets (made from Cnidium monnieri extract) 2 tablets. Continuous treatment for 5-7 days constitutes a course of treatment. Nearly a hundred cases have been observed, and most of them can be cured after one course of treatment. Trichomonas turn negative and the itching disappears; the vagina is clean and leucorrhea disappears or is significantly reduced. In addition, it has been tried on non-trichomoniasis vaginitis and can also reduce the secretion of leucorrhea. For those with cervical erosion, no adverse reactions are seen after application.

Treatment of acute exudative skin disease

Take 2 taels of Cnidium monnieri, wrap it with gauze, add 1500ml of water, boil for half an hour; soak it with cotton pad, wring it half dry, and apply warm compress Cover the local area with oil paper or plastic cloth to maintain a certain temperature and humidity, which can generally be maintained for 0.5 to 1 hour. Take it 4-6 times a day. 380 cases were clinically observed. Most of them were treated for 5-10 days, and the exudates were significantly reduced and the inflammation subsided. No side effects were found. You can also grind the Cnidium into fine powder, mix it into an ointment with Vaseline, and apply it to the affected area, 1-2 times a day. Observed 15 cases of infant eczema (erosive stage). Most of them began to reduce the exudation on the second day of medication, and then scabbed and healed.

Edit this paragraph about the legend of Cnidium monnieri

According to legend, during the Qin Dynasty, a strange disease suddenly became popular in a small village in the south of the Yangtze River. The skin of the sick person is covered with pimples of different sizes, which are extremely itchy and unbearable. Many famous local doctors are helpless. Later, a sorcerer said that there was a medicine to cure this disease growing on a small island in the East China Sea. However, the island is full of venomous snakes, and the herbs are often suppressed by the venomous snakes, making it very difficult to collect them. Finally, under the guidance of an old medicine farmer, several strong men stepped forward. On the fifth day of May, they brought realgar wine to Snake Island and sprinkled it on the poisonous snakes while looking for medicinal herbs. After all the hardships, only one person was able to carry back two baskets of herbs. Villagers boiled the seeds of this grass in water and washed them, and the disease was cured after only three or five times. Because this medicine is often found under snakes, just like the snake's bed, it is named "Cnidium" and its seeds are called "Cnidium". Although the authenticity of the above legend cannot be verified, it is absolutely true that "Cnidium monnieri" is good at treating scabies and eczema on the skin when used externally. From ancient times to the present, the Chinese medicine "Cnidium monnieri" has been regarded by doctors of all generations as an important medicine for treating skin diseases and pruritus. It can be widely used to treat ringworm, malignant sores, skin eczema, allergic dermatitis, scalp sores, female vaginal itching, trichomonas vaginitis, etc., and is often effective.

Chen Shiduo, a famous doctor in the Qing Dynasty, once said in his "Bengenxinbian": "Cnidium monnieri has very strange functions. It can be used to treat both internal and external diseases, but it is especially good for external treatment." Modern medical research has found that "Cnidium monnieri" also has sex hormone-like substances. It can improve the body's immunity, promote the hematopoietic function of human bone marrow, and protect the adrenal cortex. Therefore, it has the effect of delaying aging, reducing the toxic and side effects of chemotherapy, and prolonging life. In recent years, it has also been used to treat male impotence, sexual dysfunction, female uterine cold infertility and other diseases. Generally, boil it in water, take 3-10 grams daily internally, and 15-30 grams externally.

Edit this paragraph for clinical application of Cnidium monnieri

1. The elderly have weak kidney yang, cold yin and kidney deficiency, impotence and premature ejaculation; elderly women have redness, white discharge, and swelling and pain in the vagina. Often used synonymously with Schisandra chinensis and Cuscuta chinensis. 2. Used to treat skin eczema and pruritus, such as acute attacks of chronic eczema, erosive phase of sweat herpes, scrotal eczema, vulvar itching, scabies, tinea, etc.