hē zǐ
2 English Referencechebule [朗道汉英字典]/>
fructus chebulae [朗道汉英字典]/>
fructus terminaliae [朗道汉英字典]/>
myrobalan [朗道漢英字典]/>
myrobalan [朗道汉英字典
Terminalia chebula Retz. [Landau Chinese-English Dictionary]
chebulae,fructus [Xiangya Medical Dictionary]
medicine terminalia fruit [Xiangya Medical Dictionary]
myrobalanum [Xiangya Medical Dictionary]
Fructus Chebulae(La) [Nomenclature Review Committee of Chinese Medicine. Chinese Medicine Nomenclature (2004)]
medicine terminalia fruit [Chinese Medicine Nomenclature Validation Committee. Nomenclature of Chinese medicine (2004)]
3 OverviewCheahoko
Cheahoko is the name of the traditional Chinese medicine, out of the "Ben Cao Tu Jing". It is the dried mature fruit of Terminalia chebula Retz. or Terminalia chebula Retz. var. tomentella Kurt. from the family of Haberdashery[1].
The Pharmacopoeia of the People's Republic of China (2010 edition) contains pharmacopoeial standards for this herb.
4 Latin nameFructus Chebulae (la) (Nomenclature of Chinese Medicine (2004))
5 English namemedicine terminalia fruit (Nomenclature of Chinese Medicine (2004))
6 Alias of chebulahorehound[2].
7 SourceHaberlea is the fruit of Terminalia chebula Retz. et al. from the plant Terminalia chebula, family Apocynaceae[2].
8 PhytomorphologyDeciduous tree. Bark dark brown, branchlets often brown pilose. Leaves alternate or subopposite, leathery, elliptic or ovate, 7-16 cm long, 3-8 cm wide, entire, with green glands at the base and petiole. Spikes integrated paniculate, terminal or axillary, densely pilose; flowers small, fragrant, calyx cup-shaped, pale yellow, 5-lobed, inner surface densely hairy; corolla absent; stamens 10, in 2 whorls; ovary inferior, 1-loculed. Drupe ellipsoid, olive-shaped, 5-angled. Flowering in May-June, fruiting in January of the following year.
Born in sparse forests or forest margins on sunny slopes.
9 OriginThe chebulbul is mainly produced in Yunnan [2].
Chebulin is distributed in Guangdong, Yunnan, Guangxi.
10 Harvesting and Primary ProcessingHarvested in fall and winter when the fruit is ripe, and dried in the sun.
11 Biomedicinal propertiesThe fruit is oblong or ovoid, 2-4 cm long, 2-2.5 cm in diameter, with a yellowish brown or dark brown surface, slightly glossy, with 5-6 longitudinal ribs and irregular wrinkles. The texture is firm. The flesh is 0.2-0.4cm thick, yellowish brown or yellowish brown. Fruit kernel 1.5～2.5cm long, 1～1.5cm in diameter, light yellow, rough. Seeds are narrowly fusiform with yellowish brown seed coat. Taste sour and astringent and then sweet.
12 Sexual flavor attributionChebulin taste bitter, sour, astringent, flat; into the lung, large intestine, stomach meridian [2].
13 Functions and IndicationsChebulin has astringent intestinal astringent lung, lowering the fire and pharyngeal effect. It is used for prolonged diarrhea and dysentery, blood in the stool and prolapse of the anus, asthma and cough in lung deficiency, prolonged cough, sore throat and mute voice.
Chebulin has astringent intestines, astringent lungs, lowering the fire and pharyngeal effect[2]:
For prolonged diarrhea, prolonged dysentery, prolapse of anus[2].
Treating asthma and cough with phlegm, prolonged cough with loss of voice, chronic laryngitis[2].
Decoction: 3-6 g. For diarrhea, it should be simmered [2].
Chebulleaf: quench thirst and dysentery, decoction [2].
14 Chemical compositionChebulin fruit contains tannins, of which the main component is chebulinic acid (Chebulinic acid), chebulagic acid (Chebulagic acid), 1,3,6 tri-galloyl glucose and 1,2,3,4,6 pentagalloyl glucose [2]. It also contains mangiferolic acid, quinic acid, amino acids, and senecioside A and chebulin (Chebulin) [2].
Chebulin contains chebulinic acid (chebulin), chebulin (chebulin), chebulagic acid (chebulagic acid), original chebulin (terchebin), shikimic acid, ellagic acid, gallic acid (gallic acid), quinic acid, quinine acid and other amino acids. acid), quinic acid (quinic acid), senna glucoside A (sennoside A), tannase (tannase). Flavors flat, bitter, sour, astringent taste.
15 Pharmacological effectsChebulin decoction has inhibitory effects in vitro against dysentery bacillus, typhoid bacillus, Escherichia coli, Escherichia contortus, diphtheria bacillus, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus, and pneumococcus [2].
Chebulbul is rich in tannin, which has an astringent effect on mucosal ulcers formed during bacillary dysentery or enteritis [2].
Chebulin has a poppy-like smooth muscle antispasmodic effect [2].
Chebulin has some anti-experimental tumor effects[2].
16 Pharmacopoeial Standard of Chebulia 16.1 NameChebulia
Hezi
CHEBULAE FRUCTUS
16.2 SourceThis product is the plant of the family of the Apocynaceae, Chebulia chebula Retz. or tomentella Chebulia chebula Retz. var. tomentella Kurt. dry mature fruit. Autumn and winter fruits are harvested when ripe, remove impurities, sun-dried.
16.3 PropertiesThe product is oblong or ovoid, 2-4 cm long, 2-2.5 cm in diameter, the surface is yellowish brown or dark brown, slightly glossy, with 5-6 longitudinal ribs and irregular wrinkles, the base of the fruit has a rounded pedicel scar. The texture is firm. Flesh 0.2-0.4cm thick, yellowish brown or yellowish brown. Fruit kernel 1.5～2.5cm long, l～1.5cm in diameter, light yellow, rough, hard. Seeds narrow fusiform, about lcm long, 0.2-0.4cm in diameter, seed coat yellowish brown, cotyledons 2, white, overlapping each other circling. Gas slightly, taste sour and astringent and then sweet.
16.4 IdentificationTake 0.5g of this product (nucleated) powder, add 30ml of anhydrous ethanol, heat and reflux for 30 minutes, filtration, filtrate evaporation, residue dissolved with 5ml of methanol, through the neutral alumina column (100-200 mesh, 5g, inner diameter of 2cm), eluted with 50ml of dilute ethanol, eluent collection, evaporation, residue dissolved in 5ml of water, through C18 ( 300 mg) solid phase extraction column [3], eluted with 30% methanol 10 ml, discard 30% methanol solution, then eluted with methanol 10 ml, collect the eluate, evaporate to dryness, the residue added with methanol 1 ml to make dissolved, as a test solution. Another take chebulin control herb (nucleated) 0.5g, the same method into the control herb solution. According to the thin-layer chromatography (2010 version of the Pharmacopoeia, a Appendix VI B) test, absorb the above two solutions of 4μl, were spotted on the same silica gel G thin-layer plate, with toluene, glacial acetic acid and water (12:10:0.4) as the unfolding agent, unfolding, take out, drying, sprayed with 10% sulfuric acid in ethanol solution at 105 ℃ heated until the spots clear color, and placed in the ultraviolet lamp (365 nm) to see. In the chromatogram of the test product, in the corresponding position with the chromatogram of the control herb, the fluorescent spots of the same color.
16.5 Check 16.5.1 MoistureNot more than 13.0% (2010 version of the Pharmacopoeia, Appendix IXH, the first method).
16.5.2 Total ashnot more than 5.0% (2010 version of the Pharmacopoeia, Appendix IXK).
16.6 LeachateAccording to the water-soluble leachate method (2010 version of the Pharmacopoeia, Appendix IX A) under the item of cold immersion method, not less than 30.0%.
16.7 Chebulin tablets 16.7.1 Concoction 16.7.1.1 ChebulinRemove impurities, wash and dry. Break into pieces when used.
16.7.1.2 Meat of chebulinTake clean chebulin, soak it slightly, moisten it, remove the core and dry it.
16.7.2 Flavor and MeridianBitter, sour, astringent, flat. Attributed to the lung, large intestine meridian.
16.7.3 Functions and IndicationsAstringing the intestines to stop diarrhea, astringing the lungs to stop coughing, lowering fire to benefit the throat. It is used for prolonged diarrhea and dysentery, blood in the stool and prolapse of the anus, asthma and cough in lung deficiency, prolonged cough, sore throat and hoarseness.
16.7.4 Usage and dosage3~10g.
16.7.5 StorageIn a dry place.
16.8 Provenance