What is the role of Eucommia Bark?
DUZHONG Pinyin DUZHONG English name Eucommia Bark Skin Effect Nourishes the liver and kidneys, strengthens the muscles and bones, and calms the fetus. It is used for treating soreness of the waist and spine, impotence and weakness of the limbs, spermatorrhea, spermatorrhea, diarrhea, fatigue, urination, wetness and itchiness under the yin, restlessness of the fetus, fetal leakage and fullness of the fetus, miscarriage, and high blood pressure. Sweet, slightly pungent, warm. (1) Ben Jing: "Pungent flavor, flat." (2) "Bielu": "Sweet, warm, non-toxic." ③ "Treatise on Medicinal Properties": "Bitter in flavor." Entering the liver and kidney meridians. ①Wang Hao Gu: "Liver meridian qi." ② "Explanation of the Medicinal Properties of Lei Gong Cunning": "Enters the kidney meridian." ③ "Explanation of the Materia Medica": "Enters the lung meridian of the hand taiyin." Usage and dosage For internal use: decoction, 3-5 qian; soaked in wine or in pills or powder. Contraindications: Caution should be exercised in cases of yin deficiency and fire exuberance. ① 《本草经集注》:"恶蛇皮、元参。" ② "Materia Medica": "Should not be used for kidney deficiency and fire. That is, when used with cypress, Zhimu together." (③) "Getting and Matching Materia Medica": "It is forbidden for those with internal heat and dryness of essence and blood." 1, with cow's knee, tonifying the liver and kidneys and strengthening the muscles and bones of the power to enhance, commonly used in the treatment of insufficient liver and kidneys of the waist and leg pain and weakness of the feet and other diseases. 2、With schizandra, function of liver and kidney tonic, lumbar and knee, and solid impetus, commonly used in liver and kidney insufficiency due to various diseases. 3、With bone marrow, warming and tonifying the kidney and yang power increase, and complement the spleen, liver, not only astringent lower yuan, but also solid impetus, commonly used in kidney yang insufficiency, the lower element of the impotence of the cold, cold pain in the lumbar and knee and the lower element of the spermatorrhea, can also be used for liver and kidney insufficiency of the lumbar and knee pain, fetal restlessness, and diarrhea and other conditions of the deficiency of the spleen and kidney yang. 4, with five plus skin, both strong muscles and bones and get rid of wind-dampness, is the complementary pair of both diarrhea, suitable for the treatment of liver and kidney deficiency, wind-dampness invasion of the muscles and bones caused by lumbar and leg pain, foot and knee pain, joints are not conducive to the weakness of the lower limbs and other diseases. [1] Target Individuals Suitable for patients with hypertension, women with habitual abortion, patients with sequelae of poliomyelitis, and those with kidney qi deficiency. Caution should be exercised for those with Yin deficiency and fire exuberance. (Not suitable for those with kidney deficiency and fire blazing, i.e., when used with cypress and Zhimu). Therapeutic effect: Sweet, slightly pungent, warm in nature. Attributed to the liver and kidney meridians. Qi and moistening descending. Nourishes the liver and kidney, strengthens the muscles and bones, and tranquilizes the fetus. Indications: soreness and pain in the waist and knees, impotence, spermatorrhea, frequent urination, residual leakage of urine, hyperactivity and dizziness, rheumatism and paralysis, wetness and itchiness under the yin, restlessness of the fetus, and leakage of the fetus and miscarriage. Practice Guidelines It can be used to make tea, wine, or added to dishes as an accessory in cooking. Where there is insufficiency of the liver and kidney, soreness of the waist and knees, or impotence and weakness of the feet and knees, it can be combined with tonic bone resin and walnut kernel, etc.; this product is often used for the restlessness of the fetus or habitual following of the fetus due to the lack of solidity of the Chong Ren. It can be taken as pills with boiled jujube meat alone, or combined with Renjiu, Sanghongsheng, and Radix Rehmanniae Praeparata to enhance the effect of tonifying the kidneys and fixing the fetus; and it can be combined with Ginseng, Colla Corii Asini, and Angelica Sinensis in cases of hemorrhage in pregnancy. Synonyms: Si Xian ("Ben Jing"), Mu Mian, Si Zhong ("Bie Lu"), Jie Jie ("Ben Cao Tu Jing"), Shi Si Xian ("Supplement to the Diffractions of the Materia Medica"), Silk Lian Bark, Silk Neem Bark ("Chinese Medicine Zhi"), Rip Silk Bark ("Hunan Medicine Zhi"), Silk Cotton Bark ("Manual of Traditional Chinese Medicines") Prescription: Eucommia bark, Chuan Eucommia bark, Han Eucommia bark, Fried Eucommia bark, Salted Eucommia bark, Salt-water fried Eucommia bark, Charcoal of Eucommia bark, Charcoal of Eucommia bark, Jiao Eucommia bark, Raw Eucommia bark, etc. In the prescription, eucommia refers to raw eucommia, which is the original herb with impurities removed and shredded for raw use in medicine. Fried eucommia is also known as salted eucommia, fried eucommia in brine, roasted eucommia, burnt eucommia, etc. It is a kind of pure eucommia shredded in brine. It is a kind of net Cortex Eucommiae filaments which are mixed well with salt water and then stir-fried to a yellowish brown color with a gentle fire. It is used to lead the medicine down, tonifying the liver and kidney, and strengthening the muscles and bones. Cortex Eucommiae Charcoal is pure Cortex Eucommiae Shreds stir-fried to black brown by fire, with the inner silk broken and stored, then taken out, sprinkled with water to extinguish the sparks and dried in the sun to be used as medicine. Preferred to stop bleeding. Trade Name Mian Cortex Cortex Eucommiae: also known as Thick Cortex Eucommiae. The skin is thick, and when broken, the white silk is as much as cotton. Good quality. Sichuan Cortex Cortex Eucommiae: Produced in the Daba Mountain Range of Sichuan and the Loushan Mountain Range of Guizhou. It has the best quality and is an authentic medicinal material. Han Cortex Eucommia: Produced in Shaanxi and Hubei, and distributed in Hankou. The quality is also good. The best quality is those with thick skin, whole blocks, dry, no coarse skin, many white threads on the cross section, and black-brown color on the inner surface. Distribution of animal and plant resources Distribution in the middle reaches of the Yangtze River and southern provinces, Henan, Shaanxi, Gansu and other places are cultivated. The herbs are mainly produced in Sichuan, Shaanxi, Hubei, Henan, Guizhou and Yunnan. Harvesting and Storage In order to protect the resources, the method of partial peeling is generally used. Between Qingming and the summer solstice, select plants that have grown for 15 to 20 years or more, peel off the bark according to the size of the specification of the herbs, shave off the rough skin, and dry it in the sun. Place in a ventilated dry place. Latin Name Cortex Eucommiae Original Plant Eucommia ulmoides Oliv. 1, Eucommia ulmoides: remove the coarse skin, wash, moisten, cut into squares or silk strips, sun-dried. 2, salt Eucommia ulmoides: the first salt with the right amount of water to dissolve the Eucommia ulmoides block or silk strips, so that the brine and salt water to fully mix through the absorption, and then placed in the pot, stir-fried with a gentle fire until the degree of slightly burnt spots, remove and dry. Take out and dry. (Each 100 pounds of eucommia, with 3 pounds of salt) eucommia after frying, the eucommia gum is destroyed, the active ingredients are easy to decoction. 3, the system of charcoal: take eucommia block, placed in the pot with a martial arts fire fried to black and broken silk, but must be stocked, sprayed with brine, take out, to prevent recombination, drying that is, each eucommia block of 100 kilograms with 3 kilograms of salt, or take eucommia block, first mixed with brine absorbed and then put in a pot with a martial arts fire fried until black And break the silk to save the sex, spray out the sparks with water, take out and dry. For every 100 kilograms of Cortex Eucommiae, use 3 kilograms of salt. (1) "Lei Gong Gun Zha Lun": "Wherever you make Duzong, you must first cut off the rough skin and roast it with crisps and honey. Where to repair a catty, crisp two two, honey three two, two flavors and make a place to use." ② "Materia Medica Hook Yuan": "Cortex Eucommiae, fried in wine to break the silk." Testimonials From "Shennong Ben Cao Jing". The Classic of the Materia Medica: "Cortex Eucommiae, the people of Jiangnan said that the first leaves are taken when they are tender, called the buds of Cortex Eucommiae. The flowers and fruits are bitter and astringent, and can also be used as medicine; the wood is used as clogs, and is also used to benefit the feet." Herbs identification dry bark, for the flat plate sheet or rolled sheet, size thickness varies, generally about 3 ~ 10 mm thick, about 40 ~ 100 cm long. The outer surface is gray-brown, rough, with irregular longitudinal grooves and rhomboid transverse split lenticels, sometimes visible light gray lichen spots. But commodities have been cut off part of the rough skin, so the outer surface is light brown, smoother. The inner surface is smooth, dark purple. The texture is brittle and easy to break, and there are silver-white filaments connected with the cross-section, fine and dense, slightly stretchy. Slight gas, slightly bitter taste, chewing gelatinous residue. To skin thick and large, brown skin scraping, outside yellow-brown, inside black-brown and light, when broken white silk is good. Thin skin, cross-section less silk or thick skin with coarse skin quality. Microscopic identification: old bark cross-section: thicker layer of fallen skin. There are about 5-6 intermittent stone cell layers in the bast, each layer is about 3 columns of cells, stone cell wall is very thick; ray width 2-3 columns of cells; irregularly shaped rubbery masses scattered, to near the stone cell layer is common. In longitudinal section, the rubbery substance is present in the rubber cells. Powder: dark grayish brown. The stone cells are oblong, square, round, polygonal or irregular, 32-80 μm in diameter, 180 μm in length, 6-28 μm in wall thickness, mostly of uneven thickness, with obvious pore grooves, and some of them contain rubbery masses in the lumen. ② Rubber filaments are long and thin, slightly curved or twisted into clusters, and the surface is granular. ③ cork cells surface view polygonal, uneven wall thickening, lignification, fine pores, the cell cavity often contains orange-red material; cross-section view slightly rectangular, wall thin on one side, the other side of the thick, pore grooves obvious. Another can be seen sieve tube molecules, starch particles, and so on. Chemical composition of traditional Chinese medicine The bark of the tree contains Gutta-percha (Gutta-percha) 6-10%, the root bark contains about 10-12%, is easily soluble in ethanol, difficult to dissolve in water, hard gum. In addition, it also contains glycosides 0.142 mg%, alkaloids 0.066 mg%, pectin 6.5 mg%, fat 2.9 mg%, resin 1.76 mg%, organic acids 0.25 mg%, ketoses (2.15 mg% before hydrolysis, 3.5 mg% after hydrolysis), vitamin C 20.7 mg%, aldoses, chlorogenic acid. The fatty acid composition of the fat oil contained in the seeds is 67.38% linolenic acid, 9.97% linoleic acid, 15.81% oleic acid, 2.15% stearic acid, and 4.68% palmitic acid. The fruit contains gum up to 27%, easily soluble in ethanol, acetone and other organic solvents. Eucommia bark and leaves contain 14 kinds of lignin and lignin glycosides (ligninoglycosides), and glycosides linked to the sugar are glucopyranose. Among them, diphenyltetrahydrofuran lignin and its glycosides are pinoresinol diglycoside, etc. Pinoresinol diglycoside is the active ingredient for lowering blood pressure in Eucommia. From the skin of eucommia bark, there are also n-twentynine, n-thirtiethyl alcohol, betulin, betulin, betulinic acid, β-sitosterol, ursolic acid, vanillic acid. Eucommia bark and leaves also contain 17 kinds of free amino acids and 15 kinds of trace elements such as germanium and selenium. It also contains cyclic enol ether terpenes, 10 kinds of cyclic enol ether terpenes (iridoids) from the skin and leaves of Eucommia bark and leaves, including geniposide (geniposide), aucubin (aucubin), ajugoside (ajugoside), ulmoside (ulmoside), harpagide acetate (harpagide), and glucoside (aucubin). Glucoside (reptoside), etc., in addition to eucommia glucoside, the rest of the components of the glucoside element are β-glucoside chain linked to glucopyranose. Eucommia glucoside sugar part for isomaltose (isomaltose-glucose-α-glucoside). Origin and Sources The bark of Eucommia bark, family Eucommiaceae. Botanical form Eucommia deciduous tree, up to 20 meters high. Branchlets smooth, yellowish brown or lighter, with lamellar pith. Bark, branches and leaves contain gum. Leaves alternate; simple; elliptic or ovate, 7-15 centimeters long, 3.5-6.5 centimeters wide, apex acuminate, base broadly cuneate, margin serrate, young leaves sparsely pilose above, densely hairy below, older leaves smooth above, sparsely hairy at the veins below; petiole 1-2 centimeters long. Flowers unisexual, dioecious, opening at the same time as the leaves or before the leaves, borne in the axils of the basal bracts of annual branches, stalked; perianth absent; male flowers with 6-10 stamens; female flowers with a naked and prolonged ovary, which is 1-loculed and apically 2-forked styles. Samara ovate-oblong ellipsoid and compressed, apex depressed, containing 1 seed. Flowering April to May. Fruiting in September. Born in montane forests or cultivated. Distributed in the middle reaches of the Yangtze River and southern provinces, and cultivated in Henan, Shaanxi, and Gansu. Growth habit: prefer sunny, mild and humid climate, cold-resistant, the soil requirements are not strict, hills, plains can be planted, but also the use of sporadic land or the four sides of the cultivation. The young leaves (buds) of this plant are also used for medicinal purposes, another detailed article. In order to protect the resources, the collection is usually done by partial peeling method. In the Qingming to the summer solstice, select the growth of more than 15 to 20 years of plants, according to the size of the specification of herbs, peeling off the bark, shaving off the rough skin, sun-dried. Place in a ventilated dry place. The dried bark of the herbs, for the flat plate flaky or rolled flaky, varying in size and thickness, generally about 3 to 10 mm thick, about 40 to 100 cm long. The outer surface is gray-brown, rough, with irregular longitudinal grooves and rhomboid transverse split lenticels, sometimes visible light gray lichen spots. But commodities have been cut off part of the rough skin, so the outer surface is light brown, smoother. The inner surface is smooth, dark purple. The texture is brittle and easy to break, and there are silver-white filaments connected with the cross-section, fine and dense, slightly stretchy. Slight gas, slightly bitter taste, chewing gelatinous residue. To skin thick and large, brown skin scraping, outside yellow-brown, inside black-brown and light, when broken white silk is good. Thin skin, the section of the silk less or thick skin with thick skin quality second. Mainly produced in Sichuan, Shaanxi, Hubei, Henan, Guizhou, Yunnan. In addition, it is also produced in Jiangxi, Gansu, Hunan and Guangxi. Chemical composition of the bark contains 6-10% of dulcium gum, the root bark contains about 10-12%, is soluble in ethanol, difficult to dissolve in water hard gum. In addition, it also contains glycosides 0.142 mg%, alkaloids 0.066 mg%, pectin 6.5 mg%, fat 2.9 mg%, resin 1.76 mg%, organic acids 0.25 mg%, ketose (2.15 mg% before hydrolysis, 3.5 mg% after hydrolysis), vitamin C 20.7 mg%, aldose, chlorogenic acid. The fatty acid composition of the fatty oil contained in the seeds is 67.38% linolenic acid, 9.97% linoleic acid, 15.81% oleic acid, 2.15% stearic acid . Palmitic acid 4.68%. Fruit gum content up to 27%, soluble in ethanol, acetone and other organic solvents. Pharmacological effects ① Antihypertensive effect The extract and decoction of the bark have a long-lasting antihypertensive effect on animals. With its extract 5 ml (1 ~ 2 grams of raw medicine) to anesthetized dogs after intravenous injection to produce a significant hypotensive effect, can last 2 ~ 3 hours, showing a "fast tolerance" phenomenon. In 3 renal hypertensive dogs, the decoction was administered daily by gavage at 5-8 g/kg for 4 weeks, and the systolic blood pressure was lowered by only 8-22 mmHg (4-10%) at most, so the efficacy of the treatment was not satisfactory. The concoction and dosage form of Cortex Eucommiae have some influence on the antihypertensive effect, the decoction effect is stronger than the tincture, and the antihypertensive effect of fried Cortex Eucommiae is greater than that of raw Cortex Eucommiae. Cortex Eucommia Ulmoides has antihypertensive effect on cats, but it lasts for a short period of time, and the phenomenon of "rapid tolerance" is not significant. The hypotensive effect on rabbits with cholesterol atherosclerosis is more significant than that on normal rabbits, but it can also produce "fast tolerance". As for the principle of antihypertensive effect, it is preliminary because the active ingredient has not yet been determined. It has been proved that the acute antihypertensive effect is not related to the vagus nerve and is not affected by atropine. For isolated rabbit heart, Cortex Eucommiae was first excited in small amount and then slightly inhibited; its inhibitory effect on the heart was also reported to be related to its pH (pH between 4 and 5), and was adjusted to be excitatory for isolated hearts of both rats and rabbits. Cortex Eucommiae has a direct dilatation effect on normal rabbit ear blood vessels, but the same concentration makes experimental cholesterol atherosclerosis rabbit ear blood vessels were contraction, on the normal rabbit coronary blood vessels and renal blood vessels in the low concentration of the dilatation effect, the high concentration is the opposite, on the atherosclerosis of rabbits coronary blood vessels in the low concentration of contraction was also presented. Since its antihypertensive effect is not directly related to the heart and blood vessels, it is inferred that it is central. ②Diuretic effect The various preparations of Cortex Eucommiae have diuretic effect on anesthetized dogs, and there is no "fast tolerance" phenomenon. It also has diuretic effect on normal rats and mice. Cortex Eucommiae contains 0.4% potassium, so it is inferred that diuresis may be related to potassium. Clinical use of Cortex Eucommiae extract can reduce blood pressure in hypertensive patients and improve symptoms such as dizziness and insomnia. Large doses (20~25g/kg/day) of Cortex Eucommiae decoction to dogs by gavage can make them quiet and sleepy, and not easy to accept external stimuli. The large dose of Cortex Eucommiae also has the effect of inhibiting the central nervous system in mice. Cortex Eucommiae can inhibit the excitatory effect caused by the posterior lobe of the pituitary gland on the isolated uterus of rats and rabbits and make the uterus relax, but the isolated uterus of cats is excited inversely. Some inhibitory effects of a decoction of Cortex Eucommiae on Mycobacterium tuberculosis in the test tube have been reported. Its alcoholic infusion seems to reduce the absorption of cholesterol in the intestines of rats. Concocted Cortex Eucommia Ulmoides: Remove the coarse skin, wash, moisten, cut into squares or silk strips, and dry in the sun. Salt Cortex Eucommia Ulmoides: first use salt with appropriate amount of boiling water to dissolve, take Cortex Eucommia Ulmoides blocks or silk strips, so that with the brine is fully mixed through the absorption, and then placed in the pot, stir-fried with a gentle fire to the degree of slightly burnt spots, remove and dry. (Every 100 pounds of Cortex Eucommiae, with 3 pounds of salt) Cortex Eucommiae after frying, then Cortex Eucommiae gum is destroyed, the active ingredients are easy to decoct. (1) "Lei Gong Gun Zhi Lun": "Wherever you make duchess, you must first cut off the rough skin. It should be roasted with crisps and honey. Where to repair a catty, crisp two two, honey three two, two flavors and make a place to use." ② "Materia Medica Hook Yuan": "Cortex Eucommiae, with wine fried broken silk." Sweet, slightly pungent, warm. (1) Ben Jing: "Pungent flavor, flat." (2) "Bielu": "Sweet, warm, non-toxic." ③ "Treatise on Medicinal Properties": "Bitter in flavor." It enters the liver and kidney meridians. ①Wang Hao Gu: "Liver meridian qi." (2) "Explanation of the Medicinal Properties of Lei Gong Cunning": "Entering the kidney meridian." (3) "Explanation of the Materia Medica": "Entering the lung meridian of the hand taiyin." Functions and Indications: Nourishing the liver and kidney, strengthening the tendons and bones, and stabilizing the fetus. Treating soreness of the waist and spine, impotence of the feet and knees, residual leakage of urine, wetness and itching under the yin, fetal leakage, restlessness of the fetus, and high blood pressure. ① "This Classic": "the main waist and spine pain, tonifying the middle and benefiting the essence, firming the muscles and bones, strong will, in addition to the itchy dampness under the yin, urination leaking." ② "Other Records": "Lord feet in the soreness, do not want to trample the ground." ③ "Pharmacognosy": "treatment of kidney cold hip lumbago, waist patients with deficiency and body strong and straight, wind also. The waist is unfavorable plus and use it." (4) "Rihua Zi Materia Medica": "Treating kidney labor, lumbar spine contracture. It can be used in medicine and roasted." ⑤ Wang Hao Gu: "Moistening the dryness of the liver and tonifying the wind deficiency of the liver meridian." (6) Materia Medica Zheng: "Stopping small water dreaming, warming the uterus, and tranquilizing the fetal qi." (7) Jade Rowan Medicinal Explanation: "Benefits the liver and kidneys, nourishes sinews and bones, and removes dampness and lust from the joints. Treatment of lumbar and knee pain, leg and foot contracture." (8) "Materia Medica Rexin": "Enrich the tendons, strong Yang Road." Usage and dosage for internal use: decoction, 3-5 money; soaked in wine or into pills, bulk. Contraindications: Caution is advised for those with yin deficiency and fire exuberance. ① "Materia Medica Jing Jiezhu": "Wicked Snake Skin and Yuan Shen." ② "Materia Medica": "Should not be used by people with kidney deficiency and fire. That is, when used with cypress, Zhimu together." (③) "Getting and Matching Materia Medica": "Internal heat. It is forbidden to use it if the essence and blood are dry." (1) the treatment of lumbago: a catty of Cortex Eucommiae, Schisandra chinensis half a liter. Two things cut, divided into fourteen doses, each night to take a dose of one liter of water, soaked to five, fried three minus one, filtered juice, to sheep kidney three, four, cut down, and then boiled three, five boiled, such as the soup method, take an empty meal. Use salt, vinegar and also get it. ("Suitcase in the formula") ② treatment of lumbago: Chuan Mu Xiang one money, aniseed three money, Cortex (fried silk) three money. One bell of water, half a bell of wine, decoction, dregs and then decoction. ("living people heart system" Si Xian San) ③ treatment of stroke back pain can not be endured: Cortex Eucommiae two two (remove the rough skin, sizzling slightly yellow, filing), Salviae Miltiorrhizae two two, Rhizoma Ligustici one and a half, Gui Xin one one or two, fine Xin three. The above medicines are pounded roughly as a bulk, each serving four money, with a medium calorie of water, decocted to five minutes, remove the dregs, the second into the wine for two minutes, and then decocted for three or two boils, every time before eating, take warm. ("Sheng Hui Fang" Du Zhong San) ④ treatment of stroke, contracture of tendons and veins, weakness of the waist and knees: Du Zhong (remove the rough skin, sizzling, filing) one and a half, rhizoma rhizome one or two, epimedium (shell cracked, remove the skin. Umbilical cord) half two; on the three flavors, filed as a hemp bean, each serving five money dagger, water two marigolds, into the ginger a jujube big, patted, fried to a marigold, remove the dregs, empty heart warm service. If people traveling five miles to serve again, sweating caution outside the wind. ("General Records of the Shengji" Duzhong drink) ⑤ treatment of urinary leakage, wet itching under the yin: Sichuan Duzong four two, cumin two two (all salt, wine immersion fried), Psyllium one or two five money, Cornu Cervi Pantotrichum meat three two (all fried). *** for the end; refining honey pills, sycamore seed size. Every morning to take five money, white soup down. ("Materia Medica Huiyan") (6) treatment of women's twins restlessness: Cortex Dulcis is not counted how much, remove the coarse skin fine filing, roasted on the tile, pounded Luo for the end, boiled jujube paste pills, such as a bullet large, each serving a pill, chewed, under glutinous rice soup. ("General Records of the Shengji" Duzhong pill) (7) treatment of frequent and habitual abortions or three or four months that is abortive: in two months before, to Duzhong eight two (glutinous rice decoction soup, soaked, fried silk), two two (wine immersion, roasted; for the end), to the yam five, six two for the end of the battered pills, sycamore big. Each serving of fifty pills, empty heart under the rice drink. ("Simple single formula") ⑧ treatment of hypertension: a Duchenne, Xiaku Cao five money, red hyssop three money, watercress three two, fish loach string one or two. Simmering water service, three times a day. ("Guizhou Herbal Medicine") two Cortex Eucommiae, Scutellaria baicalensis, Xiaku Cao five money each. Decocted with water. ("Shaanxi Herbal Medicine") Clinical Application ① Treatment of Hypertension Take 30 drops of 10% Cortex Eucommia tincture each time, 3 times a day. ***Treatment of 119 cases, after 1 to 23 months of observation, the efficacy of 51 cases of satisfactory (42.8%), an average of 9.1 months of treatment; slightly improved 15 cases (12.6%); ineffective 53 cases (44.6%). No adverse reactions were found. Another 5% tincture of Cortex Eucommia each time 5 ml, 3 times a day, treatment of 124 cases, the efficacy of early hypertension is better, in the treatment of 1.5 months within 4 cases of blood pressure down to normal; for severe hypertension can not curb its development. It is believed that the improvement of conscious symptoms of dulcium is more significant than other drugs. It has been used to control the efficacy of three groups of Duchess, lisdexamfetamine, lisdexamfetamine combined with hydrazine phenylpyridazine, and the result of antihypertensive effect is the worst in Duchess, with the effective rate of 50%, and the other two groups are 90% and 95% respectively, but the reduction of self-awareness of the symptom is the best in Duchess, which accounts for 82.5%, and the other two groups are 65.1% and 61.3% respectively. Experimental observation proved that the antihypertensive effect of fried Cortex Eucommiae was greater than that of raw Cortex Eucommiae, and the antihypertensive effect of alcoholic extract was smaller than that of aqueous decoction. ② treatment of post-polio sequelae with 1.5 two Cortex Eucommia Ulmoides, 1 pig's foot; add water, simmer for 4 hours, take the juice of the medicine 2 times a day to serve; the next day will be the dregs of the medicine plus 1 pig's foot and then decocted to serve, every other day 1 dose, *** service 10 doses. Treatment of a case of two years of history of the child, used Chinese, Western medicine and new medical methods are ineffective, by using the above, while muscle massage and functional training, 1 week later, muscle power began to progress, can walk independently 30 meters; 2 weeks later can walk independently 200 meters, gait is more stable, muscle power significant progress; the third week has been able to walk independently 600 meters, gait is steady and strong.