Three main causes of thrombocytopenia: 1. Congenital dysplasia of megakaryocytes. Congenital dysplasia of megakaryocytes is one of the causes of thrombocytopenia. However, such factors are relatively rare, and megakaryocytes will appear in individual patients. and a massive decrease in platelets accompanied by congenital malformations of bones, heart, kidneys, etc. In addition, estrogen and long-term heavy drinking are also causes of thrombocytopenia, but platelets will recover after stopping drinking. 2. Physical and chemical factors that inhibit bone marrow antimetabolites, ionizing radiation, cytotoxic agents, alkylating agents and other physical and chemical factors are also the main causes of thrombocytopenia, which are usually complicated by thrombocytopenia symptoms when patients are undergoing treatment for malignant tumors, and can also cause patients to develop thrombocytopenia. The immune response may directly poison bone marrow cells, causing diffuse damage to the bone marrow and reducing the patient's whole blood count. 3. Influence of blood diseases. If a patient develops aplastic anemia due to various factors, the patient will have symptoms such as reduced bone marrow megakaryocytes and reduced platelet production. It can also be said that thrombocytopenia is an early manifestation of aplastic anemia. . This may be because the patient only recovered granulocytes and hemoglobin but not platelets after treatment. Three major causes of thrombocytopenia: Cause 1: Excessive platelet destruction is one of the causes of thrombocytopenia. Both congenital and acquired conditions can cause excessive platelet destruction. Among them, immune and non-immune conditions cause acquired excessive platelet destruction. main reason. Cause 2: Excessive retention of platelets in the spleen is also one of the main causes of thrombocytopenia. Hypersplenism often leads to excessive retention of platelets in the spleen. Cause 3: Ineffective death or decreased production of platelets can also lead to thrombocytopenia. The causes of ineffective death and decreased production of platelets mainly include acquired and hereditary. If affected by malignant tumors, infections, certain drugs, and ionizing radiation, Acquired reduction in platelet production occurs when hematopoietic stem cells proliferate in the bone marrow or damage hematopoietic stem cells. Only by cherishing and caring for yourself can you have a healthy body. Happiness is in your own hands. Shijiazhuang Red Cross Zhikui Hospital is a specialized hospital that can also treat thrombocytopenia. For the convenience of patients, an online health consultation hotline has been opened. Welcome to consult.