(1) antitussive effect: the total alkaloids and non-alkaloids of Fritillaria cirrhosa were given orally at 0.25 ~ 0.5 mg per mouse, all of which had obvious antitussive effect. The total alkaloids and Fritillaria saponin ⅰ, ⅱ and ⅲ extracted from wild and cultivated Fritillaria thunbergii in northwest Sichuan were tested by mouse sulfur dioxide induced cough method, and the alkaloids did not have antitussive effect. 0.2g/kg of Fritillaria saponin Ⅱ can obviously prolong the latent period of cough in mice, showing antitussive effect.

(2) expectorant effect: Experimental research shows that Fritillaria cirrhosa cultivated in home, wild and tissue has obvious expectorant effect.

(3) Effect on circulatory system: Bulbus Fritillariae Cirrhosae has antihypertensive effect. A very small amount of peimine and peimine can raise blood pressure. A large number of alkaloids can reduce blood pressure. antibiotic action

Bulbus Fritillariae Cirrhosae has certain antibacterial effect. 2mg/l can inhibit the growth and reproduction of Escherichia coli and Staphylococcus aureus. Fritillaria cirrhosa aqueous alkali extract (1∶25) has inhibitory effect on Nocardia stellata in vitro. Prescription selection: Treatment of cough: Fritillaria (the big one is fried with bran to make it yellow), ten pieces of donkey-hide gelatin (baked dry) and licorice (baked file), half each. The three flavors are smashed into fine powder, and two yuan is taken each time. (Fritillaria powder) Treating lung heat, cough, excessive phlegm and dry throat: one and a half parts of Fritillaria (removing heart) and almond (peeling in soup and stir-frying). The first two flavors of Dao Luo are refined honey pills, which are as big as marbles and contain phlegm and body fluid. (Fritillaria pill). Cough and dyspnea in children: Fritillaria (stir-fried with bran removed) is half of licorice (roasted). The last two flavors are smashed into powder. For example, for two or three-year-old children, every dollar is decocted in water for seven minutes to four minutes, and then I add a little bezoar powder to eat, and then I take it twice and measure the size of the child. (Fritillaria powder. 1~ 3 prescription comes from Shengji Zonglu) Treating whooping cough: Agkistrodon 5g Fritillaria 10g raw licorice 10g. The above three herbs are crushed, sieved and mixed evenly. Oral 1 time1.5 ~ 3g1day 3 times. [journal of anhui traditional chinese medical college]19843 (4): 43] Treating hematemesis, epistaxis, or the onset or cessation of which are all caused by accumulated heat in the heart meridian: one or two Fritillaria (processed to make yellow). When smashing the fine Luo is not counted, adjust the two money with warm pulp. ("Shenghui Fang") Treating lung abscess, pus vomiting, vexation, heat, stuffy cough: one or two licorice (fried file) for Fritillaria (heart-removing), Radix Asteris and Radix Platycodi (fried). Every time I take San Qian water on the sieve, I fry it for five or seven times to get rid of my cold clothes at any time. (Sishun Decoction in Criterion of Syndrome Treatment) For treating cough caused by injury storm, Fritillaria (removing heart) is three points, Flos Farfarae, Herba Ephedrae (removing root nodes), almond (soaking in soup, peeling, sharpening, Shuang Ren, frying and grinding) is one or two points, and licorice (filing) is three points. Five flavors, roughly sifted, San Qian Bi, a lamp of water, and three slices of ginger are taken for each serving, and they are fried until seven points, so that we can take them warm, regardless of time. (Fritillaria Soup in Shengji Zonglu) Treating sudden cough, dyspnea, lung flaccidity and fatigue cough after typhoid fever: one and two halves of Fritillaria (simmering slightly yellow). One or two of Platycodon grandiflorum (to remove the reed head), one or two of Glycyrrhiza uralensis Fisch (to be slightly red and filed), one or two of Zi Yuan (to wash away the seedling soil), and half two of almonds (to be soaked in soup, peeled, pointed, Shuang Ren and parched with bran to be slightly yellow). The medicine is smashed into powder, and the honey pills are as big as buttonwood. Drink 20 pills with porridge every time; As big as a marble, it is better to wrap a pill in cotton and swallow it. ("Shenghuifang" Fritillaria Pill) Treatment of lung abscess and flaccidity: one or two fritillary bulbs, one yuan each for Tianzhu Huang and Borax, and five points for Meretrix meretrix (fried with vinegar). At the end, brush the loquat leaves with honey, boil the paste as pills, and chew and swallow them. ("Medical grade" Fritillaria enclosed phlegm pills) Treating depression and chest diaphragm is not wide: removing the heart of Fritillaria, stir-frying with ginger juice, and making paste pills with ginger juice, 70 pills each time. (Ji Xiao Fang) 1 1. Resolving phlegm, reducing qi, relieving cough, relieving depression, promoting digestion and relieving bloating: one or two Fritillaria (removing heart), and half two magnolia officinalis made of ginger. Honey pills are big, and 50 pills are taken per white soup. ("Health Miscellaneous Xing") Lower milk: oysters, Anemarrhena asphodeloides and Fritillaria, which are fine powders, are mixed with pig's trotters soup. ("Herbal Decoction" Sanmu Powder) Treatment of scrofula and fecal toxicity: half a catty of Fritillaria and half a catty of Gleditsia sinensis. For fine powder, file with half a catty of Gleditsia sinensis, knead with concentrated water, and filter to make paste, powder and pill as big as buttonwood. Take fifty or seventy pills each time, and drink in the morning. ("Puji Fang" Fritillaria Pill) Treating swelling of throat obstruction: Fritillaria, Sophora Tonkinensis, Platycodon grandiflorum, Glycyrrhiza uralensis, Schizonepeta, Mint, decoction. ("Essentials of Materia Medica") Treating the initial breast abscess: Fritillaria is the end, and each time it is taken for two yuan, warm wine is adjusted, that is, both hands are pressed on the table, and the breast is hanging for a long time. ("Ren Zhai Zhi Zhi Fang") Treating cold tears and dizziness: one Fritillaria and seven peppers are the last point. ("Confucianism") Treating children's goose's mouth is full of white rot: Fritillaria is the end of the heart, half money, five points of water, a little honey, fried for three times, and wiped clean, four or five degrees a day. ("Shenghuifang")