The four main evidence of Chaihu: cold and heat, chest and hypochondriac pain and fullness, silent food and drink, heartburn and vomiting, and the seven concurrent evidence of Chaihu: chest pain without vomiting, thirst, pain in the abdomen, hardness of the coarseness of the abdomen, palpitations under the heart, dysuria, no thirst, body with a slight fever, cough; Chaihu has a significant central antipyretic and hypothermic effect, and the active ingredient is related to the saponins and volatile oils contained in the northern Chaihu saponins and volatile oils and the crude saponins in the Chaihu,

I, the role of Chaihu:

1, sedative, analgesic, antiepileptic: Chaihu crude saponin, saponin element A has a significant sedative effect, and can prolong the sleep time of mice. And it has obvious analgesic effect on experimental pain in mice.

2, hepatoprotective and choleretic: Chaihu preparation has significant antagonistic effect on experimental hepatic injury in animals, which can reduce hepatocyte degeneration and necrosis, and make the content of liver glycogen and ribonucleic acid accumulated in hepatocytes restored to normal or close to normal in a large part of the liver cells, and make the activity of serum aminotransferase decreased significantly; and it can inhibit the fibroplasia of the injured liver, promote the fibroabsorption, and reduce the occurrence of liver cirrhosis. Among them, Gan Chai Combination has the best effect. _ Bupleurum officinale increases total bile excretion with bile salt composition in dogs. Its active ingredient is flavonoid.

3, enhance the immune function: the extract of Bupleurum officinale and Bupleurum polysaccharide have immune-enhancing effects. Bei Chaihu can obviously promote sheep erythrocyte antibody formation after the second immunization in mice. The polysaccharides of Bupleurum chinense had a significant enhancing effect on the lymphocyte proliferation in mice induced by Con A and PHA, suggesting that Bupleurum chinense had an enhancing effect on T and B lymphocytes. Chaihu enhanced the phagocytosis of Kupffer cells; it enhanced the phagocytosis of mononuclear macrophages. Xiao Chaihu Tang has the effect of activating macrophages to induce IL-l in vitro.

The application of Chaihu

1, Chaihu is mostly used for external diseases, that is, it does not belong to the solar meridian evidence, and is not a Yangming meridian evidence of the Shaoyang evidence, which is the most appropriate to use. However, this formula should not be applied to the bitter mouth, dry throat and sore throat caused by external dryness; if you feel other external evils, you can add or subtract on the basis of the original formula, such as external wind-cold, add Jingwu, Fangfeng, etc.; if you feel wind-heat, add chrysanthemums, honeysuckle, etc.; if you feel summer-dampness, add patchouli and mint, etc.

2, for non-Shaoyang patients, as long as the liver and gallbladder qi pivot is not smooth, and there is dampness and heat within the spleen and stomach elevation failure, can be applied to Chai Hu, such as the treatment of various chronic gastritis, enteritis, chronic hepatitis B and other diseases are also effective.

3, Chaihu can rob the liver yin, half-summer can transform the dampness and hurt the yin, scutellaria is bitter cold and dry dampness has the effect of hurting the yin, therefore, if the liver yin or yin and blood deficiency of the body, should be careful to use this formula or in the basis of the formula with additional subtractions, such as with yin-supporting drugs.