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What are the pharmacological properties of borneol in Chinese medicine?
1. Antibacterial effect: Borneolum can inhibit or kill clinical common bacteria such as Staphylococcus aureus, Streptococcus haemolyticus B, Streptococcus viridis, etc. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) are1.0% ~1.5% and1.5% ~ respectively. Borneol also has antibacterial effect on five common fungi, such as Trichophyton rubrum, and its mechanism is related to the fact that Borneol easily penetrates the cell wall, causing cell membrane damage, destruction and changing its permeability.

2. Anti-inflammatory effect: Borneol and Isoborneol, the main components of Borneol, can both inhibit the paw edema induced by egg white in rats, and their mechanism may be related to antagonizing PGE and inhibiting the release of inflammatory mediators, but their inhibitory effects on mouse auricle swelling induced by croton oil are not exactly the same, and the effect of Borneol is not obvious.

3. Analgesic effect: After using borneol directly on laser burn wounds, the pain threshold of animal models is 2.78 times and 6.24 times higher than that of Jing Wanhong group (positive control) and normal saline group (negative control) respectively. The use of compound preparations containing borneol to treat various clinical pains has also been reported from time to time.

4. Others: Borneolum can promote the division and growth of glial cells (Schwann cell), and its effect is similar to that of musk. The optimal concentration is 0.04%, and the most vigorous growth period is 72 hours of culture. Borneol can also induce abortion in middle and late pregnancy mice, and the pregnancy termination rates are 100% and 9 1% respectively, but it has no obvious effect on early pregnancy.