The nutritional value of grapefruit is deeply loved by Chinese people.
Pomelo belongs to Rutaceae citrus fruit, alias Wendan, and there are many varieties, such as skinned Madou Wendan pomelo, Madou white pomelo, white pomelo and stone pomelo. Among them, Madou Wendan pomelo is the most well known. Because grapefruit is rich in vitamin C, according to the food ingredient database of Taiwan Province Province, every 100g grapefruit contains about 50mg of vitamin C, which is half of the recommended amount of dietary nutrients in China (the recommended daily amount of vitamin C for adults is 100mg), which has a positive effect on preventing colds and improving immunity. In addition to grapefruit pulp, grapefruit-related peripheral products are deeply loved by the public, such as citron tea, grapefruit peel and grapefruit sauce.
Sweet and sour grapefruit is rich in vitamins C, B 1, B2, protein, dietary fiber, calcium, phosphorus, iron and other minerals, with various nutritional components, which has a good auxiliary effect on the body, such as moistening the lungs and throat, invigorating the stomach and moistening the intestines. However, it is necessary for people who take certain drugs to avoid taking grapefruit as much as possible. Have you ever heard the warning that grapefruit juice can't take medicine? Because grapefruit contains ingredients similar to grapefruit, it is easy to interact with some drugs, which may lead to drug poisoning or drug rejection, and even lead to death in severe cases.
These five "drugs" should not be taken with grapefruit, and the elderly should pay more attention.
Because grapefruit contains an ingredient called "furan coumarin", this ingredient will inhibit the enzyme CYP3A4 used by the human body to metabolize certain drugs. If this enzyme doesn't work, the metabolism and decomposition speed of drugs in the body will slow down, which will lead to a long retention time of drugs in the body, an abnormally high drug concentration in the blood, and a higher dose of drugs absorbed by the body than usual, thus causing side effects and increasing the incidence of drug poisoning.
However, not every drug will have a negative effect on the interaction with coumarin. There are five main drugs that need special attention. For example, calcium channel blockers (amlodipine, felodipine), statins (atorvastatin, lovastatin, simvastatin), antiarrhythmic drugs (amiodarone) and immunosuppressants (cyclosporine), some hypnotic sedatives and antidepressants. , are all drugs that will interact, so be careful! The Hazard Mitigation Foundation reminds that the elderly, in particular, need to be more careful, because their metabolic capacity is already poor, their tolerance to high-concentration drugs is very low, and they are the main users of chronic drugs. They or their families and caregivers must pay attention to avoid the elderly taking grapefruit, grapefruit or citrus fruits at home, so as not to cause side effects of drugs and harm their health.
Classification examples combine grapefruit or grapefruit results with atorvastatin (for example, Lipitor? ) lovastatin (ex: fat? ) Simvastatin (ex: vegetarian? ) Interaction may lead to muscle diseases, rhabdomyolysis and even acute renal failure. Antihypertensive drug (calcium channel blocker) Felodipine (e.g. Propranolol? ) nifedipine (ex: Guan Dayue? ) Verapamil (ex: mind is calm? ) Amlodipine (Example: Yimaiyou? ) may cause adverse reactions such as hypotension and rapid heartbeat, and may seriously lead to ischemic myocardial infarction. Diazepam (e.g. Fan Ning? Midazolam (ex: sleep guide? Triazolam (for example: Hao? A possible antiarrhythmic drug amiodarone (for example, metoprolol? ) immunosuppressant cyclosporine (example: cintimur? Nausea, headache, paralysis, spasm, nephrotoxicity and other adverse reactions. The increase of drug concentration in blood increases the risk of adverse reactions.
Be cautious about drug safety. If in doubt, be sure to find a professional pharmacist.
And grapefruit can inhibit drug metabolism for several hours or even two or three days. Even taking it at intervals is still risky, so the best way is to "don't eat" grapefruit. However, it is rare to spend the holidays with my family, and it seems a bit unreasonable not to eat at all. Sun, a pharmacist in the pharmacy department of the Affiliated Hospital of Taipei Medical College, said that the last choice is to "have a taste". Eating one or two tablets is within the acceptable range and must not exceed this range!
If you are not sure whether your medicine will have adverse interaction with grapefruit, grapefruit and other foods, it is recommended to go to the hospital or the community pharmacy clinic near your home to ask a professional doctor or pharmacist. Don't drink or eat grapefruit before taking medicine under uncertain circumstances. Medication safety needs to be cautious. I hope everyone can have a happy and safe Mid-Autumn Festival!
Topic: Mid-Autumn Festival, Nutrition, Enzymes, Health Care.