1, acute onset, fever,

2, the oral mucosa appears scattered herpes, the size of rice grains, and the pain is obvious;

3. Herpes the size of a grain of rice appears on the palm or sole of your hand, and occasionally your hips or knees may be affected;

4, there is inflammatory blush around herpes, and there is less liquid in the blister.

Some children may be accompanied by cough, runny nose, loss of appetite, nausea, vomiting and headache.

Symptoms of severe cases of hand-foot-mouth disease:

A few cases (especially those under 3 years old) have developed rapidly. Meningitis, encephalitis (brain stem encephalitis is the most dangerous), encephalomyelitis, pulmonary edema, circulatory disorders, etc. It appears about 0-5 days after onset. Very few cases are critical and can lead to death, and the surviving cases may have sequelae.

1. Nervous system manifestations: poor mental state, lethargy, easily frightened, headache, vomiting, delirium and even coma, limb shaking, myoclonic, nystagmus, ataxia, eye movement disorder or acute flaccid paralysis convulsion. Physical examination showed that meningeal irritation sign, tendon reflex weakened or disappeared, nipple sign and other pathological signs were positive.

2. Respiratory system manifestations: shortness of breath, dyspnea or rhythm change, cyanosis of lips, cough, coughing up white, pink or bloody foam-like sputum, and wet rales or sputum can be heard in the lungs.

3. Circulatory system manifestations: pale face, patterned skin, cold limbs, cold sweat on fingers (toes), prolonged capillary refilling time. Heart rate increases or decreases, pulse decreases or even disappears, and blood pressure increases or decreases.