Precautions for the use of pituitrin ① This product is ineffective after oral administration;
② During labor, it is forbidden if the birth canal is blocked, the fetal position is not correct, the pelvis is narrow, and the cervix is not yet open.
③ When there is no warning of delivery, the induced labor is invalid;
④ The dosage should be controlled correctly. The dosage should be small when inducing labor, and it can be increased appropriately when there is disease after delivery. When the dosage is large, it can cause high blood pressure, oliguria and abdominal pain. Pituitrin is a water-soluble component extracted from the posterior pituitary of pigs and cows, which contains oxytocin and vasopressin. Oxytocin has a selective effect on uterine smooth muscle, and its intensity depends on the dosage and physiological state of uterus. Pituitrin is mainly used for diabetes insipidus and pulmonary hemorrhage, and oxytocin induces labor. Pituitrin is a hormone secreted by human pituitary gland, which mainly includes vasopressin and oxytocin. Long-term use of pituitrin will lead to hypertension and other symptoms, and any drug has side effects. As long as it is used according to the instructions, the occurrence of side effects will be reduced.
Patients should pay attention to rest, light diet, eat more vegetables and fruits, and drink more water. During the process of pituitrin, local skin tissue changes should be seen after extravasation, lidocaine local sealing and magnesium sulfate wet and hot compress all have certain effects.
If there is a large area of tissue necrosis, the surgeon is required to deal with it. After taking the medicine, if you have pallor, sweating, palpitation, chest tightness, abdominal pain, anaphylactic shock, etc., you should stop taking the medicine immediately. You can't use this product to induce labor in cases of abnormal fetal position, pelvic isthmus and obstruction of birth canal.
Pituitrin affects pulmonary embolism. Pituitrin is a hemostatic drug, which is mainly suitable for the following diseases.
First, postpartum hemorrhage caused by poor uterine contraction, postpartum uterine involution is not complete, because of the booster effect, it is now less used in obstetrics.
Second, it is pulmonary hemorrhage.
Third, it is due to bleeding from esophageal and gastric varices.
Fourth, it is diabetes insipidus.
Acute pulmonary embolism is usually treated with anticoagulants for a long time, and warfarin is the commonly used anticoagulant. Therefore, patients should measure their coagulation function for a long time when using warfarin to avoid pulmonary hemorrhage caused by coagulation dysfunction. Once pulmonary hemorrhage occurs, we should deal with it in time.
If the effective concentration of warfarin is not reached, anticoagulation should be continued. Hemoptysis due to pulmonary embolism cannot be treated with hemostatic drugs, and the anticoagulation is not up to standard. If excessive anticoagulation leads to hemoptysis, stop using anticoagulants, use heparin and low molecular weight heparin, use protamine against warfarin, and use vitamin K.
Therefore, we should try not to treat pulmonary hemorrhage caused by pulmonary embolism with pituitrin.