Recurrence of allergic rhinitis and catarrhal conjunctivitis should be paid attention to in spring, and anti-allergic probiotics can be added in advance to prevent it.
Pollen allergy catarrh syndrome in spring: what about allergic rhinitis, conjunctivitis and asthma? Experts say that supplementing anti-allergic probiotics in advance can effectively prevent allergic rhinitis, conjunctivitis and asthma syndrome caused by pollen allergy in spring.
Every year from March to May, when the spring blossoms, the alternation of seasons can easily make some people with allergic constitution appear cold-like. In recent years, it has been found that allergic rhinitis is easily caused by a cold in spring, and it is easy to recur in the same season every year, and it is easier to be diagnosed after more than two years.
Allergic rhinoconjunctivitis is the collective name of allergic rhinitis and allergic conjunctivitis, because allergic inflammation of the upper respiratory tract of allergic rhinitis is very easy to develop along the nasolacrimal duct to the eyes, leading to allergic rhinoconjunctivitis, which is one of the most common allergic diseases in spring and autumn. Because the disease often occurs after allergic rhinitis, it is called allergic rhinoconjunctivitis, which is the most common type of allergic conjunctivitis. Allergic rhinoconjunctivitis caused by pollen allergy in spring (also called catarrhal rhinoconjunctivitis in spring) is the main allergen of the disease. The allergens of patients were mainly dust mites and pollen allergies. Some patients have more attacks in spring and autumn, but it may be related to dust mite allergy that can occur all year round. Because of the perennial attack, it is easy to be misdiagnosed as trachoma or other diseases. According to statistics, more than 5% people in the world suffer from allergic rhinoconjunctivitis. In recent years, due to the use of eye cosmetics, wearing contact lenses, aggravated air pollution and other factors, its incidence rate has further increased. Therefore, it is of great significance to correctly understand allergic rhinoconjunctivitis and rationally use drugs.
nosogenesis
Allergic rhinitis-conjunctivitis is mainly caused by allergic reactions caused by the contact of conjunctival tissue of patients with allergic rhinitis with pollen and dust mites. This situation often occurs for no reason, so many patients will mistakenly think that it is related to too much contact with computers. A small number of patients are often close to the eyes, such as perfume, cosmetics, drugs, contact lenses and their care solutions. These allergens enter the eyes, causing the conjunctival mast cells to release allergens such as histamine, which in turn dilate local capillaries, resulting in redness, swelling and itching in the eyes. Allergic rhinoconjunctivitis is mainly a type I allergic reaction mediated by IgE. Anyone who is genetically or physically susceptible to a specific antigen, when exposed to this allergen, can lead to immediate or delayed allergic rhinoconjunctivitis, often accompanied by allergic rhinitis.
These allergens enter the eyes and combine with immunoglobulin E(IgE) on the mast cells of conjunctiva, leading to the release of histamine from the mast cells, which will dilate local small blood vessels and produce symptoms of redness, swelling and itching. Allergens include pollen, dust, wet and cold air, dust mites, animal hair, soap, perfume, cosmetics, medicines, contact lenses and their care solutions, etc. Because people's individual constitutions are very different, different people have different allergens. The most common allergic substance causing allergic rhinoconjunctivitis is plant pollen, and the symptoms of this allergic rhinoconjunctivitis are mostly seasonal. If the allergic substance is dust, dust mites or animal hair, etc., because these allergens exist all the year round, the symptoms of allergies are continuous all year round, and the symptoms are mild, but they may be aggravated with different seasons.
Many allergic rhinoconjunctivitis are self-limited, so the main purpose of treatment is to relieve symptoms and avoid sequelae. Getting rid of allergens is the most effective treatment. Contact with possible allergens should be avoided as far as possible, such as paying attention to mattress hygiene, avoiding contact with pollen, stopping wearing contact lenses and keeping indoor air circulation. In addition to oral anti-inflammatory drugs, topical antihistamine eye drops can achieve satisfactory curative effect, and mast cell stabilizer-cromoglycate sodium eye drops (such as Xinrunqing) can not only treat and prevent allergic rhinoconjunctivitis, but also be a common drug. Glucocorticoid is usually used only when other drugs are ineffective. Because of its side effects, it should be used with caution under the guidance of a doctor. In addition, there are desensitization treatment and surgical treatment.
On July 8th, the world's first "World Allergy Day", Academician Zhong Nanshan, President of Chinese Medical Association, pointed out that there are more than 200 million people suffering from allergic diseases in China, and desensitization has been recognized as an effective therapy.
Academician Zhong Nanshan introduced that at present, 22% of the people in the world suffer from allergic diseases such as allergic rhinitis, allergic rhinoconjunctivitis, allergic asthma, allergic pharyngitis, etc., and the rate is increasing by 23 times every 10 year, and it is estimated that it will reach 40% of the global population in 20 10 year. By analogy, at present, more than 200 million people in China suffer from allergic diseases, which should be paid attention to.
Generalized allergic rhinomembranitis can be divided into five types:
Hay fever rhinoconjunctivitis (also known as seasonal allergic rhinoconjunctivitis), contact allergic rhinoconjunctivitis, rhinoconjunctivitis with giant breasts, spring catarrhal keratoconjunctivitis and allergic keratoconjunctivitis. Allergic rhinoconjunctivitis (including seasonal, perennial and contact), rhinoconjunctivitis with giant breasts, keratoconjunctivitis in spring and allergic keratoconjunctivitis. Seasonal allergic rhinoconjunctivitis is the most common in young and middle-aged people, with rapid onset, which can occur when exposed to allergens, and the symptoms are relieved when separated from allergens. The main difference between perennial and seasonal is that allergic symptoms exist all the year round. Perennial allergic rhinoconjunctivitis can be seen at any age, and there is often other allergic history in the early stage. Some spring keratoconjunctivitis and allergic rhinoconjunctivitis can cause corneal complications and even harm vision. Contact allergic rhinoconjunctivitis has a clear contact history, such as drug or cosmetic contact history. There is a history of wearing contact lenses (contact lenses) in rhinoconjunctivitis with giant breasts. Keratoconjunctivitis in spring is more common in children, and often occurs or aggravates in spring and summer.
Clinical symptoms:
The typical symptoms of allergic rhinoconjunctivitis are itchy eyes, itchy nose, sneezing, runny nose and stuffy nose, and children show rubbing their noses and eyes.
Eye itching, sneezing accompanied by nasal itching and runny nose are almost the same symptoms of various types of allergic rhinoconjunctivitis, but other symptoms, such as nasal congestion, tearing, burning sensation and secretion, lack specificity and are often easily confused with other ocular surface diseases. The clinical manifestations are pale nasal mucosa, edema, watery secretion, diffuse conjunctival congestion, edema and nipple and follicular hyperplasia. The closer to the corner of the eye, the more serious the situation is. Generally, the patient has no eye pain, no obvious visual impairment and normal pupils.
The main manifestation of allergic rhinoconjunctivitis is strange itching of eyes, which is different from ordinary itching. This kind of itching is often very strong and unbearable, so it is called strange itching in medicine. Because of allergic rhinitis, patients are often accompanied by symptoms of allergic rhinitis such as sneezing, runny nose and stuffy nose. In addition, it also shows conjunctival congestion, edema, mucus secretion, often accompanied by eyelid skin redness. These symptoms will be good or bad in the allergic season, and they will recur, which is related to the climate and the activities of patients. Generally speaking, in warm and dry days, symptoms will get worse. Some patients may have nasal allergic symptoms besides eye discomfort, which is also called allergic rhinoconjunctivitis clinically.
In addition, conjunctival congestion, edema, mucus secretion, eyelid skin redness and other symptoms, and the closer to the corner of the eye, the more serious the situation, the patient generally has no eye pain, no obvious visual impairment, and normal pupils. Its symptoms will change with the seasons, which means that in addition to accidents related to patients' allergic constitution, climate change and patients' activities are important factors. Generally speaking, the symptoms will get worse in warm and dry days when flowers are in full bloom. Some patients may have nasal allergic symptoms besides eye discomfort, which is also called allergic rhinitis and conjunctivitis clinically.
Allergic rhinomembranitis in children;
Children's tissues and organs are not yet mature, so the conjunctival mucosa is highly permeable, which naturally makes them more prone to allergic rhinoconjunctivitis. Adults with allergic rhinoconjunctivitis have allergic history in childhood, and their symptoms, such as tears, burning sensation and secretions, are similar to other ocular surface diseases, so it is easy to be misdiagnosed. Therefore, I would like to remind you that when your child often rubs his eyes at a certain time, or blinks frequently, it is possible that he is suffering from allergic rhinoconjunctivitis accompanied by rubbing his nose. Ordinary anti-inflammatory eye drops have no effect at all, and even other eye diseases appear because of long-term wrong treatment. We should actively treat allergic rhinitis and desensitization to improve allergic constitution.
New direction of reducing IgE desensitization
Human beings live in an environment full of pathogenic microorganisms, and the immune system is an important defense for human survival. The immune system can distinguish between the enemy and ourselves and invade harmful substances. This mechanism enables human beings to survive on the earth for more than 100,000 years. However, the immune system is not precise, and sometimes it makes mistakes. When the immune system begins to carry out unnecessary battles about some harmless substances, the human body becomes a battlefield and manifests itself in various organs. This is the so-called allergic disease.
There are two ways for a healthy immune system ──Th 1 and Th2. These two ways need to be balanced. If Th2' s immune way is too active, it will cause allergies. The immune system of people with allergic constitution is that TH2 excretion is too high and TH 1 excretion is lacking, which leads to human immune imbalance.
Allergy is an immune disease, which is an imbalance of immune function in human body. In the clinical investigation, patients with allergic constitution often find that many allergic diseases can be seen in the same patient. Compared with normal people, patients with allergic constitution have significantly higher serum IgE, more mast cells and more IgE receptors on the cell membrane. Clinical medicine has proved that Kangminyuan anti-allergic probiotics play an important role in regulating the composition of helper T cells and their cytokines on IgE. According to the variety of excreted cytokines, the immune function divides helper cells into two subgroups: TH 1 and TH2. Cytokines excreted by TH2 cells play an important role in antibody formation and allergic reaction. TH 1 and TH2 are mutually regulated by cytokines. In healthy conditions, TH 1 and TH2 are balanced and regulated by helper T cells at the same time. When helper T cells are deficient in regulation ability or come into contact with some heterosexual protein or fine molecules (such as dust mites, pollen or seafood, etc.), TH2 is over-activated, resulting in excessive secretion of TH2 cell hormones, which leads to the increase of IgE.
Kang minyuan's new anti-allergic probiotic therapy;
Some people who are allergic to pollen should go out as little as possible in the season with a lot of pollen, or wear goggles when going out to reduce allergens from entering the eyes. Inevitable allergens should be desensitized to the corresponding allergens. Because some patients can't find out the exact allergens, or the types of allergens are complex and difficult to find out one by one, it is difficult to prevent and desensitize, which is the fundamental reason why allergic rhinoconjunctivitis recurs and is not easy to be completely cured.
It should be pointed out that drug allergy treatment can only control allergic symptoms, and it is difficult to completely cure allergic rhinoconjunctivitis, which is one of the reasons why allergic rhinoconjunctivitis can not be cured for a long time. The World Health Organization (WHO) has recognized the efficacy of high-quality and standardized probiotic specific immunotherapy for allergic rhinitis and allergic asthma, and recommended it to the whole world. It is considered that a few anti-allergic probiotics Kangminyuan (patented anti-allergic probiotics, China's patent number is 200710128018. x) can neutralize the allergenic factor IgE in vivo. At the same time, anti-allergic probiotics can promote the secretion of IFN-r(r- interferon) in spleen cells, directly reduce the synthesis of IgE, and help immune cells to adjust the balance of TH 1 and TH2. Kang Minyuan's probiotic specific immunotherapy can control the recurrence of allergic rhinitis and asthma before the onset of allergies in spring, which has been approved by most scholars and achieved good results.
If you can't determine the allergen at the moment, then, first of all, we should improve the living environment, especially the air quality or indoor temperature, so as to reduce the impact of allergens. Secondly, we should pay attention to nutrition and exercise, the law of life and rest, and enhance physical fitness. Because the improvement of physical health can improve the body's potential for allergic attacks and reduce and slow down allergic attacks. Thirdly, local cold compress or ice compress can be used to relieve discomfort symptoms, artificial tears can be used to locally apply eyes, and washing can also be used to greatly reduce the concentration of allergens and inflammatory factors and improve symptoms.
By supplementing Kangminyuan, an antiallergic probiotic, to strengthen and correct the immune allergic reaction, normal immune response can be induced. These two combined antiallergic therapies can effectively prevent and treat catarrhal symptoms of allergy in autumn and greatly reduce the severity of allergy, which has attracted much attention.