Constipated patients go to the hospital, in order to find the cause of constipation, usually need a colonoscopy. Colorectal melanosis is a constipated patient to do colonoscopy found. Colonoscopy of the normal colon mucosa is reddish, smooth and flat mucosa, vascular texture is clearly visible. Colorectal melanosis of the intestinal mucosa color was brown, brown or dark brown changes, which can be seen between the gray-white network, stripes, like a leopard skin-like diffuse distribution of the colorectal mucosa, part of the pigmentation was granular, vascular texture fuzzy or even disappeared, endoscopic field of view dim. The darkening of the colorectal mucosa was prominent in the rectum and sigmoid colon, and was milder above the sigmoid colon.

With the increased incidence of constipation and the popularization of colonoscopy, the detection rate of colorectal melanosis has risen significantly in recent years. It is a non-inflammatory benign lesion characterized by pigmentation of the colorectal mucosa, and it is said to be a benign lesion because the elimination of the causative factors can be reversed after the darkening of the colon. I have met a 60-year-old woman, because of constipation, high blood fat, buy their own laxatives to eat, continuous detoxification diet pills for more than 3 years, so that later to eat laxatives can not be relieved of stools only to come to the clinic, colonoscopy showed that the black lesions of the large intestine. I told the patient if constipation can be dietary adjustments, eat more crude fiber food more vegetables and fruits, enhance physical exercise, even if the medication should not be taken for a long time containing anthraquinone laxatives, such as: fruit guide, senna, rhubarb, aloe vera, and so on. This patient according to what I said to do, a year after the review, the color of the colon mucosa is basically back to normal.

Although constipation in the elderly, middle-aged, young people have occurred, but colonoscopy for colorectal melanosis of the middle-aged and elderly women and elderly men, these patients **** the same characteristics: a long history of constipation, and the second is the abuse of anthraquinone drugs for a long time in large doses. Modern medical research believes that: long-term constipation

, long service anthraquinone drugs is the main cause of colorectal melanosis. There are also a small number of patients with chronic inflammatory bowel disease, even without the use of laxatives, can lead to colorectal melanosis. There are no specific drugs for the treatment of colorectal melanosis, and with the development of the disease, the function of the colon will be gradually lost, while increasing the risk of cancer.