The time for cooking the large intestine can be changed according to personal preference and the size of the ingredients. After boiling the large intestine in boiling water, continue to cook for 15 to 3 minutes to ensure that the large intestine is thoroughly cooked. The key to cooking the large intestine is to ensure that the internal temperature reaches the level of safe eating, making it soft and easy to digest. Use a food thermometer to check the internal temperature of the large intestine to ensure that it reaches at least 16 F (71 C) to ensure food safety.