1. Anti-inflammatory; SD rats were gavaged with 200% Taohong Siwu Decoction. The results showed that both the low dose group (8g/kg) and the high dose group (16g/kg) could significantly inhibit the proliferation of rat granulation tissue induced by plastic ring, and the inhibition rates were 28.83% and 3 1.68% respectively. At the same time, increasing the weight of thymus has no obvious effect on the weight of other organs. It can also reduce the permeability of blood vessels.
2. Hypolipidemic: This prescription has a good effect on lowering serum cholesterol, especially in the high-dose group (16g/kg), and it also has a downward trend on triglycerides. After 7.5g/kg continuous administration of 10, the total cholesterol content in liver tissue decreased significantly, with 42.19 6.20μ g/mg in the administration group and 51.52 6.78μ g/mg in the control group, and the triglyceride content in liver also decreased significantly. At the same time, it can obviously reduce the liver index of hyperlipidemia rats, which is 36.86 2.05 mg/g in the treatment group and 41.75 3.15 mg/g in the control group. There was no significant effect on serum total cholesterol and serum triglyceride content. There was no significant effect on serum low density lipoprotein cholesterol. The results suggest that the drug can reduce liver lipid by increasing the excretion and transport of liver lipid to blood in vitro.
3. Vasodilation: This prescription can dilate the coronary artery of isolated guinea pig heart and increase the coronary blood flow. It was found that Ligusticum Chuanxiong and Angelica sinensis had the strongest effect, and there was a synergistic effect between the components. After this prescription is infused into the blood vessels of rats' lower limbs, the vascular resistance can be significantly reduced. Disassembly analysis showed that Angelica sinensis, Carthamus tinctorius and Ligusticum chuanxiong had the strongest effects, while Rehmannia glutinosa and Paeonia lactiflora had the strongest effects. Peach kernel has a weak effect, and the whole prescription has the strongest effect.
4. Anti-fatigue and hypoxia tolerance: mice were given Taohong Siwu decoction concentrate (15g crude drug /kg body weight). The hypoxia tolerance time and swimming time (minutes) of the experimental group were 276.0 565438 0.6 and 240.7 65438 0.9, respectively, while that of the control group was 233.4 535.9.
5. Anti-shock: The dogs with burn shock were given Taohong Siwu Decoction injection (crude drug112g/100 ml). The urine volume was significantly higher than that of the control group, and the survival time of burned dogs was prolonged.
6. Supplementing trace elements: The contents of major elements such as sodium, magnesium, phosphorus, sulfur, potassium and calcium necessary for human body in Taohong Siwu Decoction are high, and all the essential trace elements except tin are 16.
Modern application
Taohong Siwu Decoction is a famous medicine for promoting blood circulation and removing blood stasis. It is widely used in modern clinic, far beyond the application scope of gynecology. It is widely used in internal medicine, surgery, pediatrics, ophthalmology and otolaryngology, and there are many clinical reports. The prescription can be used for treating angina pectoris of coronary heart disease, chronic glomerulonephritis, migraine, epilepsy, diabetic peripheral neuropathy, functional uterine bleeding, dysmenorrhea, female climacteric syndrome, thromboangiitis obliterans, thrombocytopenic purpura in children, urticaria and fundus hemorrhage.