ferritin is a kind of protein with large molecular weight, which is the main storage form of iron. The normal upper limit of ferritin determination is 4ng/ml, and some tumors often rise and exceed this value, which are common in acute leukemia, Hodgkin's disease, lung cancer, colon cancer, liver cancer and prostate cancer. Detection of ferritin has diagnostic value for liver metastatic tumors. The ferritin content in 76% patients with liver metastasis is higher than 4ng/ml. Combined detection with AFP, especially in patients with liver cancer with normal AFP, can improve the diagnostic rate. The increase of ferritin may be caused by cell necrosis, blocked erythropoiesis or increased synthesis in tumor tissue.

The determination of ferritin is suitable for understanding the iron metabolism in the body. Detecting ferritin at the initial stage of treatment can reflect the iron storage in the body at that time, and can find the shortage of iron storage in reticuloendothelial system at an early stage. Clinically, the threshold of 2ng/ml can effectively judge the iron deficiency in the latent period and prompt the exhaustion of iron storage. Under normal circumstances, the stored iron can be used for hemoglobin synthesis, and when it is lower than 12ng/ml, it is judged as iron deficiency in the latent period. The above two measured values do not need further laboratory reference materials, even under the condition of normal blood cell morphology. If accompanied by small cell hypopigmentation anemia, it can be suggested that there is iron deficiency. If the ferritin level is high, the possibility of abnormal iron supply is ruled out, which reflects the situation of excessive iron in the body.

Normal reference value:

Adult male: 3-4ng/ml

Adult female: 13-15ng/ml

We generally think that it is of little significance for your situation in clinical work, because ferritin is not a tumor-specific indicator.

ferritin is a B globulin that binds to iron in serum, and the increase is seen in malignant tumor, aplastic anemia, sideroblastic anemia, chronic hemolytic anemia, liver disease, myocardial infarction, acute infection, lead poisoning and anemia caused by vitamin B6 deficiency. Increased ferritin release: such as acute hepatitis, hepatocyte necrosis, etc. It's not necessarily cancer, but it's better to have a detailed examination so that you can rest assured! Keep a good attitude.