2. Local symptoms develop slowly. In the early stage, it was sporadic joint pain, which gradually aggravated and turned into frequent pain. When exercising, the pain is aggravated, with tenderness, and the pain can spread to other parts. For example, the pain of hip tuberculosis often spreads to the knee joint. Therefore, patients should pay attention to hip joint examination when complaining of knee joint pain. Muscle spasm-contracture is caused by pain during activity, which limits the automatic and passive activities of joints. Persistent muscle spasm-contracture can cause joint contracture or deformation, and the muscles of the affected limb will collapse due to disuse-contraction. Joint deformity, pathological dislocation or limb shortening due to fracture or epiphyseal growth in the late stage. In spinal tuberculosis, fracture, vertebral collapse, abscess and granulation tissue formation can compress the spinal cord and lead to paraplegia. Cold abscess often appears in joint tuberculosis such as spinal tuberculosis. If puncture is performed, it may be complicated with infection, aggravating symptoms, and forming sinus wound for a long time. The onset of osteoarticular tuberculosis is mostly slow, and the systemic symptoms are hidden. Patients may have low fever, burnout, night sweats, loss of appetite and emaciation, anemia and positive tuberculin test. Only a few patients have acute attacks and high fever of about 39 degrees besides the above symptoms. With the development of the lesion, bone joints and vertebrae are damaged, which can lead to deformity and even paralysis. Dr. Jin Guan said: Bone tuberculosis needs timely treatment.