This product must reduce the 11-position ketone group to the 11-position hydroxyl group in the liver to show pharmacological activity. The physiological half-life is 60 minutes.
The distribution in the body is highest in the liver, followed by plasma, cerebrospinal fluid, pleural effusion, ascites, and kidney. Most of the product in the blood
is bound to plasma proteins, free and bound. Metabolites of this type are excreted in the urine, some are excreted in the original form, and a small part can be excreted in breast milk.