Ligusticum chuanxiong is a relatively common traditional Chinese medicine. We may rarely see chuanxiong in life, but we may see the ingredients of chuanxiong in some medicines for promoting blood circulation and removing blood stasis. Ligusticum chuanxiong has good blood-activating properties. It has the effect of removing blood stasis and can be used to treat high blood pressure and high blood lipids. So, what is the role of Ligusticum chuanxiong in medicine? What are the medicinal effects of Ligusticum chuanxiong?

Ligusticum chuanxiong is the rhizome of the Umbelliferae plant Ligusticum chuanxiong Hort. It is mainly produced in Sichuan, Guizhou, and Yunnan, and those produced in Sichuan are of high quality. Department of artificial cultivation. Excavate in May, remove sediment, dry in the sun, and then remove fibrous roots. When used, slice it raw or roast it in wine.

The medicinal properties are pungent and warm. Returns to the liver, gallbladder, and pericardium meridians.

Effects: Promote blood circulation and promote Qi, dispel wind and relieve pain.

Application

1. Syndrome of blood stasis and qi stagnation and pain. This product is pungent, dispersing and warming. It can not only activate blood circulation and remove blood stasis, but also promote qi and relieve pain. It is a "qi medicine in the blood" and has the effect of unblocking qi and blood. Therefore, it can treat chest, flank and abdominal pain caused by qi stagnation and blood stasis. If it is used to treat chest pain caused by blood stasis in the heart, it is often used with Salvia miltiorrhiza, cinnamon twig, and sandalwood. If it is used to treat hypochondriac pain caused by liver qi stagnation, it is often used with Bupleurum, white peony root, and Cyperus rotundus, such as Bupleurum Shugan Powder. ("Jingyue Quanshu"); such as blood stasis in the liver, accumulation of lumps, and tingling pain in the chest and hypochondrium, it is mostly used with peach kernels and safflower, such as Xuefu Zhuyu Decoction ("Yi Lin Gai Cuo"). If it is used to treat injuries caused by falls, blood stasis, swelling and pain, it can be used with frankincense, myrrh, notoginseng and other medicines.

Ligusticum chuanxiong is good at "lowering the menstrual flow and relieving stagnation". It is an important gynecological medicine. It can activate blood circulation and regulate menstruation, and can be used to treat various obstetric and gynecological diseases. For the treatment of blood stasis, amenorrhea and dysmenorrhea, it is often used with red peony root and peach kernel, such as Xuefu Zhuyu Decoction ("Yi Lin Gai Cuo"); if it is cold coagulation and blood stasis, it can be used with Guixin, Angelicae, etc., such as warm Jing Decoction ("Women's Complete Prescriptions"); if it is used to treat postpartum lochia and abdominal pain caused by blood stasis, it can be combined with angelica root, peach kernel, paojiang, etc., such as Shenghua Decoction ("Fu Qingzhu Nvke"); if it is used to treat irregular menstruation, menstrual period Before or after the treatment, motherwort, angelica, etc. can be combined, such as motherwort and golden elixir ("Medical Insight").

2. Headache, rheumatic arthralgia. This product, Xin Wensheng Powder, can "go up the head", dispel wind and relieve pain, and is an important medicine for treating headaches. It can be used according to the compatibility of headaches caused by wind-cold, wind-heat, rheumatism, blood deficiency, and blood stasis. Therefore, Li Dongyuan said, "It must be used for headaches." Ligusticum chuanxiong". To treat headache caused by wind and cold, it can be used with Qianghuo, Asarum, and Angelica dahurica, such as Ligusticum chuanxiong tea powder ("Heji Bureau Prescription"); if used with chrysanthemum, gypsum, and silkworm, it can be used to treat headache due to wind heat, such as Ligusticum chuanxiong powder ("Health Care") If treating rheumatism and headache, it can be combined with Qianghuo, Duhuo and Fangfeng, such as Qianghuo Shengshi Decoction ("Discrimination of Internal and External Injuries"); combined with Angelica sinensis and white peony root, taking advantage of the effectiveness of this product in dispelling wind and relieving pain, it can treat blood deficiency headaches. For example, flavored Siwu Decoction ("Jin Gui Yi"); if it is used to treat blood stasis and headache, it can be combined with red peony root and musk, such as Tongqiao Huoxue Decoction ("Yi Lin Gai Cuo").

This product is pungent and warm, can dispel wind, dredge collaterals and relieve pain, and can also treat rheumatic arthralgia. It is often used with Duhuo, Qingenzi, Fangfeng, Guizhi and other medicines, such as Duhuo Jisheng Decoction ("Qianjin") square").

Usage and Dosage: Decoct and take, 3~9g.

Use with caution if you have bleeding syndrome of yin deficiency, excessive fire, excessive sweating, excessive heat and no blood stasis, and pregnant women.

Summary of ancient books

1. "Shen Nong's Materia Medica": "It is mainly caused by stroke entering the brain, headache, cold paralysis, slow tendons and pulses, golden sores, and a woman with blood clots and childlessness."

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2. "Compendium of Materia Medica": "Ligusticum rhizome ascends the head, regulates menstrual water downwards, relieves stagnation in the middle, and is a qi medicine in the blood. It is tasted as a medicine for Angelica sinensis. It is not only effective in treating blood, but also has magical effects in treating qi. It also tastes pungent and yang, and the qi is easy to flow without being stuck in the yin. Although it enters the blood, it can remove all wind and regulate all qi."

3. "New Edition of Materia Medica": "Ligusticum chuanxiong. It can clear blood blockage, disperse external factors, treat head wind and sores, and relieve pain of sores. This medicine can be used as a adjuvant or as a adjuvant. There is a worry of dissipation. If it is used solely to relieve pain, the pain will stop and there will be concern of sudden death."

Modern research

1. Chemical composition: This product contains alkaloids. (such as ligustrazine), volatile oils (mainly ligustilide, fennelene, etc.), phenolic substances (such as ferulic acid), visfatin and vitamin A, folic acid, sucrose, sterols, fatty oils, etc.

2. Pharmacological effects: Ligustrazine can dilate coronary arteries, increase coronary blood flow, improve myocardial blood oxygen supply, and reduce myocardial oxygen consumption; ligustrazine can dilate cerebral blood vessels and reduce vascular resistance. , significantly increase blood flow in the brain and limbs, improve microcirculation; can reduce platelet surface activity, inhibit platelet aggregation, and prevent the formation of thrombus; the neutral component of ferulic acid contained in it promotes uterine smooth muscle in small doses and inhibits uterine smooth muscle in large doses; decoction The agent has a sedative effect on the central nervous system of animals, and has an obvious and long-lasting antihypertensive effect; it can accelerate the absorption of local hematoma in fractures and promote the formation of callus; it has anti-vitamin E deficiency effect; it can inhibit a variety of bacilli; it has antihistamine and choleretic effect.

3. Clinical research: Ligusticum chuanxiong is widely used clinically. For example: use equal parts of Chuanxiong and safflower to make tablets, and take them orally 3 times a day, 4 tablets each time (each tablet contains 1.25 grams of each of Chuanxiong and safflower). 84 cases of coronary heart disease and angina pectoris were treated, and 83 cases were effective. (Beijing Regional Coronary Heart Disease Cooperative Group. Data Collection (Second Series), 1972, 12). Intravenous infusion of 80-100 ml of ligustrazine into 500 ml of 5% glucose solution once a day, 10 times as one course of treatment, treated 66 cases of ischemic stroke in the acute stage, 154 cases in the recovery stage, and 47 cases in the sequelae stage. Results: The effective rate was 100% in the acute phase, 95.4% in the recovery phase, and 70.2% in the sequelae phase. (Shaanxi Traditional Chinese Medicine, 1988. (9): 408). Use 24-28 grams of Ligusticum chuanxiong, 30 ml of white wine, and 250 ml of water. After soaking for 1 hour, cover and simmer over a slow fire for 2 servings. People who don’t drink can just add water and stew and take it. 29 cases of functional uterine bleeding were treated, and all were effective. (Shaanxi Traditional Chinese Medicine, 1990, 11(4): 150).

Efficacy

(1) Promoting blood circulation and promoting Qi

① Used for patients with coronary heart disease and angina pectoris, symptoms of chest tightness, suffocation, and frequent precordial tenderness. Use it together with safflower, salvia, balm, and red peony root, Guanxin No. 2 prescription.

② It is used for diseases caused by qi and blood stasis, such as early menstruation, excessive amount and red color, it is blood heat, and can be used with raw rehmannia root, peony bark, and angelica root; late menstruation, 1 to 2 Once a month, if you suffer from waist and abdominal pain during menstruation and multi-colored leucorrhea, it can be used equally with Angelica sinensis, Paojiang, Eucommia ulmoides and Cinnamon.

③ For dysmenorrhea, if there is severe waist and abdominal pain before menstruation and menstruation occurs one day after the pain, it can be used with angelica, peach kernel, and safflower; if amenorrhea is not enough and there is no physical discomfort, it can be used with angelica and peach kernel. , dried ginger, and cinnamon can be used together; if you have postpartum abdominal pain, use it together with Angelica sinensis and Paojiang.

④ It is used for bruises and local swelling and pain. It can be used together with gardenia, peach kernel and safflower.

(2) Expelling wind and relieving pain

① For colds and headaches, for those with wind-cold, it can be used with Schizonepeta, Fangfeng, and Angelica dahurica; for those with wind-heat, it can be used with chrysanthemum, Use with mint.

② Used for rheumatic arthralgia, it can be used equally with Qianghuo, Duhuo, and Fangfeng.

(3) Promoting qi and relieving depression

① Used for distension and pain in the abdomen and ribs above cholecystitis. It can be used equally with Bupleurum and Scutellaria baicalensis.

② It is used for gastritis, abdominal distension and pain, acid vomiting, heartburn and other symptoms. It can be used with dandelion and costus.