Can bird flu be cured?

Avian influenza is a severe infectious disease caused by type A influenza virus and mainly affects poultry. The virus not only has many serotypes, but also has many virus-carrying animals in nature and the strains are prone to mutation, which makes the prevention and control of avian influenza more difficult. Highly pathogenic avian influenza in poultry is characterized by rapid disease spread, high mortality rate, and great production harm. In the 20th century, 17 large-scale bird flu outbreaks occurred around the world. However, after entering the 1990s, the incidence rate of bird flu accelerated and its spread became wider. Especially in the past 13 years, 11 large-scale highly pathogenic avian influenza epidemics have occurred around the world, which not only poses a great threat to the poultry industry, but also some powerful strains of avian influenza belonging to type A influenza viruses. The pathogenic virus strain may also cause influenza in humans, so this disease has attracted great attention at home and abroad.

1. Avian influenza pathogens and their characteristics

Avian influenza viruses are members of the genus Influenzavirus. According to the differences in the nucleoprotein and matrix protein of influenza viruses, influenza viruses are divided into A, B, Type C. Type A mainly infects poultry, but humans and a variety of terrestrial and aquatic mammals and poultry are infected. Types B and C mainly infect humans. According to the differences in hemagglutinin (HA) and neuraminidase (NA) on the surface of the virus particles, there are 15 different types of avian influenza viruses based on hemagglutinin and 9 different types of neuraminidase. After they are combined with each other, more than 100 serotypes of strains can be produced. There is no cross-immune reaction between sera, and not only do strains often change, but the pathogenicity and lesions of each strain also vary. Not the same. For example, domestic ducks and geese often carried the virus without getting sick before 2000, but since then highly pathogenic avian influenza has also occurred in ducks and geese. Among the more than 100 currently known avian influenza strains, the vast majority are low-pathogenic strains. High-pathogenic strains are mainly concentrated in two subtypes: H5 and H7. The pathogenicity of H9 subtype is as high as The virulence is also strong, but lower than the previous two types. Internationally, poultry infected with H7 and H5 subtypes of avian influenza must be culled, and European and American countries have also adopted culling measures against cases caused by the H9 subtype. Judging from the epidemic situation of highly pathogenic avian influenza that has occurred worldwide since the 20th century, the main pathogenic strains are H5N1, H7N3, H5N9, H5N8, H5N2, H7N7, H7N4, H5N2, and H7N1. my country conducted a survey on epidemic strains of avian influenza from 2000 to 2003, and collected 107 strains of avian influenza viruses, including 95 strains of H5N1, 11 strains of H9N2, and 1 strain of H7N2. Therefore, the avian influenza epidemic in my country is mainly caused by two subtypes of avian influenza viruses, H5 and H9, which provides a basis for the production and immunization of avian influenza vaccines.

The avian influenza virus is relatively sensitive to the external environment and its resistance is weak. Sunlight, drying, heating, and various disinfectants all have a killing effect on it. For example, the virus can be inactivated by heating it at 60 degrees for 10 minutes and heating it at 70 degrees for 2 minutes. The virus can be inactivated in direct sunlight for 40-48 hours. Various disinfectants such as sodium hydroxide, disinfectant, Baidu, bleaching powder, formalin, and peracetic acid can effectively kill viruses at commonly used concentrations. Stacked and fermented poultry manure can kill all viruses in 10-20 days. The avian influenza virus is highly resistant to low temperature and humidity and can survive for a long time. The virus in feces can survive for 30-35 days at 4 degrees Celsius and 7 days at 20 degrees Celsius; the virus can survive in frozen poultry meat and bone marrow for 10 months. The virus survives longer in cool and humid natural environments, and avian influenza viruses can often be isolated from water in lakes and ponds where waterfowl are active.

2. The prevalence and symptoms of avian influenza

Avian influenza occurs mostly in the alternating seasons of winter-spring and autumn-winter. It is mainly spread horizontally, but the onset of illness lasts 3-4 days in breeding poultry. The virus can be isolated from eggs and transmitted vertically through the eggs. The source of infection can come from infected and diseased poultry, or from wild birds and migratory waterfowl. Pathogens contaminate the environment, feed, and drinking water through secretions, excretions, and corpses, and are infected through direct or indirect contact. The respiratory tract and digestive tract are the main routes of infection.

The incubation period for poultry infected with avian influenza ranges from a few hours to a few days, and the symptoms vary depending on the bird species, age, pathogenicity of the virus strain, and whether there is secondary infection.

Avian influenza in poultry generally has no characteristic symptoms. The main symptoms are elevated body temperature, depression, decreased or stopped feed intake, loose feathers, and a decrease in egg production of hens ranging from 15 to 70%. There are respiratory symptoms, such as coughing, sneezing, difficulty breathing, and purple combs. Sick birds shed tears and have edema on their heads and faces. Some have neurological symptoms, head and neck torsion, and ataxia. Those with a longer course of disease are often accompanied by secondary infections. Acute outbreaks caused by virulent strains may result in large numbers of dead chickens without obvious symptoms, and the mortality rate can reach 80-100%. Mortality rates in non-acute outbreaks range from 10-50%.

Based on the incidence of avian influenza in recent years, the occurrence of avian influenza in poultry has the following characteristics: First, avian influenza occurs in a certain area. Although there are many virus serotypes of avian influenza, the virus that causes the disease is The strains are relatively single, and it is rare for two or more strains to have the same effect. Second, in addition to the virulence of the virus, the degree of damage caused by the disease is also related to the type of poultry. Those who are sensitive to chickens may not be sensitive to ducks and geese. Third, the same poultry species, high-yielding and fast-growing poultry, are more sensitive than local breed poultry. The fourth is the age of poultry. The resistance of old chickens is stronger than that of young high-yielding laying hens. The fifth is the health status of poultry. If the health status of the poultry group is good, the disease losses will be small, and the degree of disease reaction will be lighter than that of sick and weak poultry. The sixth is to cope with the situation. Unstressed birds responded less than stressed ones. Seventh, whether there is secondary infection or not. If poultry is simply infected with avian influenza without secondary infection, the loss will be less than that of poultry with secondary infection. If bird flu occurs, early detection and early use of antibiotics to control secondary infections can effectively reduce the incidence and losses. Eighth, the immunity effect of fast broiler chickens on H9 subtype vaccine is not ideal, and the reasons need to be further studied. Ninth, chickens with higher Newcastle disease antibody levels will suffer less loss when avian influenza occurs than chickens with low antibody levels. This may be due to the interferon produced by Newcastle disease immunity acting on the avian influenza virus.

3. Prevention and Control Measures

1. Carry out immunization

Immunization is the most important measure to control the epidemic of avian influenza. Currently, there are two main types of bird flu vaccines: monovalent and bivalent. Since there is usually only one serotype of bird flu prevalent in a certain area, it is feasible to grasp the prevailing strains of local epidemics and vaccinate with monovalent vaccines. This can help to accurately Monitor the epidemic. When the serotype is unclear in the area where the disease occurs, 2-3-valent vaccine can be used for immunization. The protection period after vaccine immunization can generally last up to 6 months, but in order to maintain a reliable immune effect, booster vaccination should usually be done every three months. It is recommended that the first dose is 0.3 ml for chickens and laying ducks aged 5-15 days, and 0.5 ml for larger meat ducks and geese, by subcutaneous or intramuscular injection. The second dose is 50-60 days old, 1 ml for meat ducks and geese, and 0.5 ml for chickens and laying ducks. The three exemptions are taken before delivery, 2-3 ml for geese, 1-2 ml for ducks, and 0.5 ml for chickens. Commercial laying poultry and breeding poultry can receive four vaccinations at the age of 40 weeks in the mid-laying period.

2. Treatment

Poultry with highly pathogenic avian influenza should be culled resolutely. If avian influenza with medium or low pathogenicity occurs, it can be treated with drugs.

(1) Antiviral: Mix 100-200 mg of ribavirin per kilogram of material and use it continuously for 4-5 days; or use adamantine at 10-25 mg per kilogram of body weight in drinking water for 4-5 days . In addition, the traditional Chinese medicine Daqingye, Isatis root, Huanglian, and Astragalus can also be decoctioned in water for poultry to drink.

(2) Control secondary infections: When poultry are found to have symptoms similar to avian influenza, antibiotics should be used to control secondary infections as soon as possible. For example, use 50-100PPm enrofloxacin in drinking water for 4-5 days; add 5 grams of oxytetracycline per 100 kilograms of feed, etc. In order to improve the physical fitness and disease resistance of poultry, multi-dimensional electrolytes can be added to the drinking water at the same time.

3. Strengthen comprehensive control measures against the epidemic of avian influenza

(1) Do not introduce or transfer fresh poultry products from epidemic areas or areas where the epidemic situation is unknown.

(2) The poultry farm raises a single variety of poultry, does not mix different varieties of poultry or livestock, and implements an "all in, all out" feeding system; the poultry farm and its staff do not raise Other livestock and poultry.

(3) Control outsiders and vehicles from entering the poultry farm. If they really need to enter, they must be disinfected. Vehicles transporting feed and poultry products during production should be dedicated separately.

(4) Control other animals from carrying poisons.

No tall trees should be planted in the poultry farms, and lawns should be used as a green environment as much as possible to prevent the gathering of wild birds; rodent eradication activities are often carried out, and animals such as pigs, dogs, and cats are not raised in the production areas. Although these animals are currently free of avian influenza diseases , but often poisonous.

(5) Prepare your own drinking water system, using deep well water or tap water instead of river, lake, or pond water. Lakes and ponds used for raising ducks and geese should be kept in a fixed water area to prevent wild birds and other livestock from entering. If possible, they should be disinfected regularly.

(6) Poultry manure and litter are accumulated, fermented or burned. Stacked fermentation takes no less than 20 days.

(7) Do not bring fresh livestock and poultry products from outside into the poultry farm. Poultry workers must wear work clothes, work boots, and masks when going to work, and must change clothes when entering and leaving the poultry farm.

(8) Strengthen feeding and management. In high-incidence areas, peracetic acid, sodium hypochlorite, etc. can be used to carry out poultry disinfection and environmental disinfection 1-2 times a day, and poultry disinfection is usually carried out every 2-3 days. Reduce the stress response of poultry as much as possible. If necessary, add 2% of vitamin C and 1% of vitamin E in drinking water or feed to improve the anti-stress ability of poultry. Provide the feed necessary for production, growth and development, keep the feed fresh and at full price, and enhance the physique of the poultry. Improve the breeding environment and provide appropriate temperature, humidity, density, and light; strengthen ventilation in the poultry house to keep the air fresh; frequently remove feces and clean the poultry house and environment to keep the production environment clean and hygienic.

(9) After each batch of poultry is released from the cage, the period of emptying shall be no less than 3 weeks. During this period, follow the instructions of cleaning-cleaning-drying-disinfection-cleaning-drying-disinfecting-again. Cleaning - The final closed and fumigated poultry house cleaning and disinfection process is used to process the poultry house; use two or more disinfectants to remove pathogenic residues in the poultry house and prevent pathogens from infecting the next batch of poultry. Can broiler chickens get avian influenza?

What does it mean? Did you become sick after eating chickens containing avian influenza viruses, or did the chickens contract avian influenza

Can people who are infected by eating infected chickens be cured of avian influenza?

< p> The morbidity and mortality of avian influenza vary widely, depending on the bird species and strain, as well as age, environment and concurrent infections, with generally high morbidity and low mortality. In highly pathogenic viral infections, morbidity and mortality can reach 100%. Can mild bird flu be cured?

If it is mild bird flu, it can usually be cured, and severe cases are rare. If you are worried, it is best to go to a tertiary hospital. The equipment and technology are relatively comprehensive, which is conducive to consultation and comprehensive diagnosis and treatment. Can avian influenza h7n9 be cured?

It is very easy to cure. The so-called human avian influenza disease occurs when the lower respiratory tract is infected. It presents acute fever symptoms when it first develops. For example, the fever caused by avian influenza disease can reach 39 degrees in about ten minutes. When a person has a fever, bacteria They will also reproduce quickly.

According to the characteristics of current influenza viruses, for example, this disease is mainly contracted in winter and spring because of cold weather. If the avian influenza virus is inhaled into the respiratory tract, the body will feel very sick for a long time. You can only get this disease when it's cold. When the body is cold, people's resistance can only resist the cold. The cold directly acts on the body, greatly reducing or disappearing the body's ability to resist the reproduction of germs and viruses in the body. At this time, the germs and viruses will multiply rapidly in the body until the disease occurs. , this is how common cold and flu viral diseases occur.

On the other hand, even if the influenza virus is inhaled into the respiratory tract, as long as the body does not feel very cold for a long time, the germs and viruses will not multiply in the body and the disease will not occur. This is why in cold weather Sometimes, a few people get this disease.

Based on the above characteristics, the so-called bird flu disease can be treated with antipyretic drugs in time. After the fever is reduced, the influenza virus dies very quickly in the body, and then the effective antibacterial drug Luo Hong is used. To prevent bacterial double infection, you must also pay special attention to keeping your body warm. According to this treatment, the most timely and effective treatment will cure the disease in two days. Improper treatment may be life-threatening. The above is actual experience. Can H7N9 avian influenza be cured?

According to news reports, it can be cured as long as you seek medical treatment. I'm afraid it will take me a few days to find out... Can bird flu be cured?

In fact, many cases have been cured.

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According to the characteristics of the current influenza virus,

as long as the fever is reduced in time with antipyretic drugs,

coupled with effective antibacterial drugs such as roxithromycin, < /p>

In addition, you should pay special attention to keeping your body warm.

Follow this treatment.

The most timely treatment will take two days to recover.

Improper treatment includes: Danger to life,

This is an answer based on actual experience.

I wish you a happy new year.