Evidence-based medicine has confirmed that lipid-lowering therapy plays an important role in the prevention and treatment of cardiovascular and cerebrovascular diseases, especially in the primary and secondary prevention of atherosclerosis and coronary heart disease. Lipid-lowering therapy can be different. Improve patient's long-term prognosis. Chinese patent medicines such as Zhibitai Capsules, Jiangzhi Tongluo Soft Capsules, etc. can not only effectively improve symptoms related to hyperlipidemia, but also minimize the side effects caused by long-term medication and achieve both symptomatic and symptomatic treatment.
Zhibitai capsule is composed of red yeast rice, hawthorn, Atractylodes rhizome, and Alisma. It has the effects of eliminating phlegm and blood stasis, strengthening the spleen and stomach. It is mainly used to treat hyperlipidemia caused by phlegm and blood stasis and unfavorable Qi and blood. Symptoms include dizziness, chest tightness, abdominal distension, loss of appetite, mental fatigue, etc.
The origin of the Zhibitai capsule formula can be traced back to the ancient prescription "Alismatis Decoction" in "The Synopsis of the Golden Chamber" written by the medical sage Zhang Zhongjing. It is a pure traditional Chinese medicine preparation refined by adding red yeast rice and hawthorn to the ancient prescription "Alismatis Decoction" and combining it with modern scientific and technological means. Traditional medicine believes that the basic pathogenesis of hyperlipidemia is deficiency in origin and excess in excess. The formula of Zhibitai Capsules combines the functions of "strengthening the spleen, expelling dampness, activating blood circulation and removing blood stasis" to treat the pathogenesis of hyperlipidemia.
Modern pharmacological research shows that the specially prepared red yeast rice contains 15 kinds of natural monacolin, a homologue of statins, among which natural monacolin K is the most potent, and natural monacolin K is the acid form. Lovastatin suggests that Zhibitai capsules actually contain statins and have clear lipid-lowering effects.
The main active ingredients in hawthorn are flavonoids, triterpenes and organic acids. Triterpenoids and flavonoids have the effects of lowering blood lipids, protecting blood vessels, dilating coronary arteries, improving myocardial function and lowering blood pressure. Oleanolic acid and ursolic acid among triterpenoids have good effects on liver protection, enzyme reduction, and anti-inflammation. Moreover, triterpenoid ursolic acid and flavonoid hyperoside can reduce lipids while increasing blood lipids. Superoxide dismutase activity, thereby improving vascular endothelial function and conducive to the prevention and treatment of cardiovascular diseases.
Alisma can reduce plasma total cholesterol. The reason may be that while inhibiting the absorption of exogenous total cholesterol, it also interferes with the metabolism of endogenous total cholesterol and resists lipid peroxidation. Atractylodes can significantly inhibit platelet aggregation and is beneficial to the treatment of atherosclerosis. At the same time, its lipophilic extract has a significant effect on reducing plasma total cholesterol and LDL-C levels and increasing HDL-C levels.
The reasonable compatibility of the four kinds of traditional Chinese medicine makes Zhibitai have the effect of lowering blood lipid levels, relieving physical and mental fatigue and general weakness, strengthening the spleen and stomach, and improving the metabolism and absorption capacity of the gastrointestinal tract. In addition, Zipita can also inhibit cholesterol synthesis, reduce the absorption of cholesterol and triglycerides, promote cholesterol metabolism, improve vascular endothelial function, eliminate carotid artery plaque, promote insulin release, and lower blood sugar.
Jiangzhi Tongluo soft capsule, the main ingredient is turmeric extract, which has the effects of promoting blood circulation and qi, lowering lipids and removing turbidity. It is suitable for patients with hyperlipidemia, such as distension and pain in the chest and hypochondrium, tingling in the precordium, chest tightness, petechiae or petechiae on the tip of the tongue, stringy or astringent pulse, etc., which are due to blood stasis and qi stagnation.
Modern pharmacological research shows that curcumin can accelerate triglyceride synthesis by inhibiting the synthesis of cholesterol and fatty acids, promoting the conversion of fat into sugar, and increasing the activities of plasma lipolytic enzymes, lipoprotein esterase and liver esterase. And the metabolism of triglyceride-rich lipoproteins, thereby exerting a blood lipid-lowering effect, and has pharmacological effects such as eliminating free radicals, anti-inflammation, antioxidant, anticoagulation, promoting fibrinolysis, and inhibiting the proliferation of vascular smooth muscle cells.
Curcumin and its derivatives can reduce total cholesterol, triglycerides, low-density lipoprotein cholesterol, and increase high-density lipoprotein cholesterol. It has the dual effects of improving atherosclerosis risk factors (lipid regulation, blood pressure lowering, etc.) and anti-atherosclerosis (anti-inflammation, antioxidant, anti-platelet aggregation, endothelial cell protection), and the two synergize. It plays an important role in preventing and treating cardiovascular and cerebrovascular diseases. Curcumin has also been found to resist damage to liver cells by oxygen free radicals, thereby protecting liver cells.
For patients with hyperlipidemia, it is often necessary to use combined medications. The more commonly used combination regimens are: statins plus fenofibrate or statins plus niacin. However, combined use often aggravates the patient's adverse effects. reaction, especially aggravation of liver damage. Because Jiangzhi Tongluo Soft Capsules have clear lipid-regulating effects and unique liver-protective effects, clinicians have an additional choice in the treatment of hyperlipidemia, especially patients with abnormal liver function.
In short, traditional Chinese medicine has its own unique advantages in lowering blood lipids and protecting liver, improving symptoms of hyperlipidemia, and protecting cardiovascular and cerebrovascular diseases. Zhibitai Capsules can not only lower blood lipids, but also improve dizziness in patients. , chest tightness, abdominal distension, loss of appetite, and symptoms of fatigue. Jiangzhi Tongluo Soft Capsule can not only lower blood lipids, but also improve patients' symptoms such as chest and hypochondrium swelling and pain, precordial tingling, and chest tightness. It can be used based on the actual situation.