Different uses, different contraindications. Different uses: hollow powder is usually used to make medicines such as methadol and benzoic acid. And macaroni is usually used to make amiodarone and other drugs. Contraindications are different: hollow powder is not suitable for those who are allergic to it, and it is not suitable for pregnant women. And macaroni is not suitable for patients suffering from serious heart disease, kidney disease and peptic ulcer to avoid aggravating the condition.